Zobrazeno 1 - 10
of 628
pro vyhledávání: '"Marion Kiechle"'
Autor:
Maximilian Riedel, Katharina Kaefinger, Antonia Stuehrenberg, Viktoria Ritter, Niklas Amann, Anna Graf, Florian Recker, Evelyn Klein, Marion Kiechle, Fabian Riedel, Bastian Meyer
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundChat Generative Pre-Trained Transformer (ChatGPT) is an artificial learning and large language model tool developed by OpenAI in 2022. It utilizes deep learning algorithms to process natural language and generate responses, which renders it
Externí odkaz:
https://doaj.org/article/099dd837406c4dbf8a0617e090d61839
Autor:
Bjoern F. Kraemer, Irina Hennis, Anne Karge, Anne Katrin Kraemer, Tobias F. Dreyer, Marion Kiechle, Bettina Kuschel, Holger Bronger
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-9 (2022)
Abstract Background Thrombocytopenia is a feared complication of preeclampsia (PE) that can additionally complicate the disease course and that carries a poor prognosis. The disease mechanisms of PE on a platelet level are poorly understood and only
Externí odkaz:
https://doaj.org/article/896cfbf6d15d4ab9aa50ccb880912453
Autor:
Aurelia Noske, Daniel-Christoph Wagner, Kristina Schwamborn, Sebastian Foersch, Katja Steiger, Marion Kiechle, Dirk Oettler, Siranush Karapetyan, Alexander Hapfelmeier, Wilfried Roth, Wilko Weichert
Publikováno v:
Breast, Vol 60, Iss , Pp 238-244 (2021)
Different immunohistochemical programmed death-ligand 1 (PD-L1) assays and scorings have been reported to yield variable results in triple-negative breast cancer (TNBC). We compared the analytical concordance and reproducibility of four clinically re
Externí odkaz:
https://doaj.org/article/6df245d0b4404ea2aae7789f9bb50efa
Autor:
Alexia Xanthopoulos, Ann-Kathrin Samt, Christiane Guder, Nicholas Taylor, Erika Roberts, Hannah Herf, Verena Messner, Anskar Trill, Katharina Larissa Kreszentia Holzmann, Marion Kiechle, Vanadin Seifert-Klauss, Sebastian Zschaeck, Imke Schatka, Robert Tauber, Robert Schmidt, Katrin Enste, Alan Graham Pockley, Dominik Lobinger, Gabriele Multhoff
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2276 (2023)
Heat shock protein 70 (Hsp70) is frequently overexpressed in many different tumor types. However, Hsp70 has also been shown to be selectively presented on the plasma membrane of tumor cells, but not normal cells, and this membrane form of Hsp70 (mHsp
Externí odkaz:
https://doaj.org/article/3c919c64bc3e434f99ce1ffdba62a71e
Autor:
Fabian Stögbauer, Barbara Geß, Christine Brambs, Manuela Lautizi, Tim Kacprowski, Iordanis Ourailidis, Holger Bronger, Marion Kiechle, Aurelia Noske, Gisela Keller, Moritz Jesinghaus, Christopher Poremba, Wilko Weichert, Melanie Boxberg
Publikováno v:
Cancers, Vol 15, Iss 15, p 3832 (2023)
The molecular characterization of endometrial endometrioid adenocarcinomas has provided major advances in its prognostic stratification. However, risk assessment of microsatellite instability (MSI) and copy-number (CN)-low cases remains a challenge.
Externí odkaz:
https://doaj.org/article/8c9f10bc21774cdfb770e89b4290cc9a
Publikováno v:
BMC Women's Health, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background The influence of lifestyle factors on the quality of life, incidence and tumor recurrence has been evaluated in several studies and is gaining increasing importance in cancer research. However, the extent of the influence of such
Externí odkaz:
https://doaj.org/article/798fd79effef4887ad1688ff8e0c49cc
Autor:
Anne Esser, Leonie Neirich, Sabine Grill, Stephan C. Bischoff, Martin Halle, Michael Siniatchkin, Maryam Yahiaoui-Doktor, Marion Kiechle, Jacqueline Lammert
Publikováno v:
Nutrients, Vol 15, Iss 6, p 1396 (2023)
Background: The Mediterranean diet (MD) is an anti-inflammatory diet linked to improved health-related quality of life (HRQoL). Germline (g)BRCA1/2 mutation carriers have an increased risk of developing breast cancer and are often exposed to severe c
Externí odkaz:
https://doaj.org/article/1bd870a2aed24101aad9ddfcb552388c
Autor:
Weiwei Gong, Yueyang Liu, Eleftherios P. Diamandis, Marion Kiechle, Holger Bronger, Julia Dorn, Tobias Dreyer, Viktor Magdolen
Publikováno v:
Journal of Ovarian Research, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Background High-grade serous ovarian cancer (HGSOC) is the most common and lethal subtype of ovarian cancer. A growing body of evidence suggests tumor-supporting roles of several members of the kallikrein-related peptidase (KLK) family, incl
Externí odkaz:
https://doaj.org/article/b15da64539f7442f89f6e7a76a319849
Autor:
Weiwei Gong, Yueyang Liu, Sarah Preis, Xiaocong Geng, Agnes Petit-Courty, Marion Kiechle, Alexander Muckenhuber, Tobias Dreyer, Julia Dorn, Yves Courty, Viktor Magdolen
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-9 (2020)
Abstract Background The serine protease KLK12 belongs to the human fifteen-member family of kallikrein-related peptidases. Differential expression accompanied by either increased or decreased enzymatic activity has been linked to several diseases inc
Externí odkaz:
https://doaj.org/article/4e2b9d1e553c49b0a3ed87bdb9432a3d
Risk stratification in luminal-type breast cancer: Comparison of Ki-67 with EndoPredict test results
Autor:
Aurelia Noske, Sophie-Isabelle Anders, Johannes Ettl, Alexander Hapfelmeier, Katja Steiger, Katja Specht, Wilko Weichert, Marion Kiechle, Evelyn Klein
Publikováno v:
Breast, Vol 49, Iss , Pp 101-107 (2020)
Objectives: Adjuvant chemotherapy decision in patients with hormone receptor positive, HER2 negative breast cancer (BC) is challenging. Ki-67 is widely used for adjuvant therapy decision in BC. The multigene assay EndoPredict (EP) has shown to provid
Externí odkaz:
https://doaj.org/article/aa20ea5f89a6427fa45e237c963d272f