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pro vyhledávání: '"Marion J. Fultz"'
Autor:
Jian Jun Gao, Michael B. Filla, Marion J. Fultz, Stefanie N. Vogel, Stephen W. Russell, William J. Murphy
Publikováno v:
The Journal of Immunology. 161:4803-4810
We have examined the role of Stat1α in the induction by LPS of the mouse inducible nitric oxide synthase (EC 1.14.13.39) gene. LPS induced both the tyrosine phosphorylation of Stat1α and the production of nitric oxide in a time- and dose-dependent
Autor:
Cindy A. Salkowski, Stefanie N. Vogel, Pin-Yu Perera, Sheila A. Barber, R. McNally, Marion J. Fultz
Publikováno v:
Journal of Endotoxin Research. 3:19-27
LPS-stimulated macrophages produce cytokines which, at appropriate levels, direct successful immune responses against harmful pathogens. However, excessive cytokine production, as seen in endotoxemia, results in pathophysiological damage to the host.
Publikováno v:
Infection and Immunity. 63:601-608
Macrophages secrete interferon (IFN), as well as other cytokines, following lipopolysaccharide (LPS) stimulation. The interferon regulatory factors (IRFs) comprise a family of DNA-binding proteins that have been implicated in the transcriptional regu
Autor:
Marion J. Fultz, Stefanie N. Vogel
Publikováno v:
Journal of Leukocyte Biology. 51:300-304
Peritoneal exudate macrophages from C3H/OuJ (Lpsn) and C3H/HeJ (Lpsd) mice were treated with interferon α (IFN-α), and isotype-specific phagocytosis and gene expression were measured. IFN-α selectively augments phagocytosis of IgG2a, with a highly
Autor:
Marion J. Fultz, Bruce A. Schoneboom, Leslie C. McKinney, Thomas H Miller, Franziska B. Grieder
Publikováno v:
Journal of neurovirology. 5(4)
Venezuelan equine encephalitis virus (VEE) produces an acute infection in humans and induces a well-characterized cytopathic effect in neurons of the central nervous system (CNS). However, little is known about the role of glial cells in response to
Publikováno v:
International immunology. 5(11)
In this paper we report that macrophages can be stimulated to express detectable levels of IFN-gamma-specific mRNA. Macrophages from lipopolysaccharide (LPS)-responsive, C3H/OuJ mice are induced by LPS to increase steady-state levels of IFN-gamma-spe
Publikováno v:
Infection and Immunity. 57:432-437
Using a modification of the splenic focus assay, we analyzed the Salmonella typhimurium-specific B-cell repertoire in salmonella-susceptible BALB/c mice. Although these mice normally succumbed to salmonella infection before antibody was produced, the
Publikováno v:
Journal of Interferon Research. 3:153-160
The role of interferon (IFN) as a specific modulator of macrophage receptor and cell surface antigen expression has only recently been established. We previously demonstrated that macrophages deriv...
Publikováno v:
European Journal of Immunology. 17:1137-1143
To determine whether the expression of surface IgD (sIgD) influences the extent of the expressed B cell repertoire, the clonal diversity of the B cell population in mice treated chronically with anti-IgD (delta) antibodies has been compared with the