Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Marion J Gijbels"'
Autor:
Simone L. Schonkeren, Meike S. Thijssen, Musa Idris, Kim Wouters, Joëlle de Vaan, Andreas Teubner, Marion J. Gijbels, Werend Boesmans, Veerle Melotte
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The enteric nervous system (ENS) is a large and complex part of the peripheral nervous system, and it is vital for gut homeostasis. To study the ENS, different hyper- and hypo-innervated model systems have been developed. The NSE-Noggin mous
Externí odkaz:
https://doaj.org/article/2f1f4a5c64f7470e8697c082d203f6cf
Autor:
Pathricia V Tilstam, Marion J Gijbels, Mohamed Habbeddine, Céline Cudejko, Yaw Asare, Wendy Theelen, Baixue Zhou, Yvonne Döring, Maik Drechsler, Lukas Pawig, Sakine Simsekyilmaz, Rory R Koenen, Menno P J de Winther, Toby Lawrence, Jürgen Bernhagen, Alma Zernecke, Christian Weber, Heidi Noels
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87452 (2014)
BackgroundThe Ikkα kinase, a subunit of the NF-κB-activating IKK complex, has emerged as an important regulator of inflammatory gene expression. However, the role of Ikkα-mediated phosphorylation in haematopoiesis and atherogenesis remains unexplo
Externí odkaz:
https://doaj.org/article/4c1509550b444460abf7231c1a2b2fe3
Autor:
Nadine Jetten, Nadia Roumans, Marion J Gijbels, Andrea Romano, Mark J Post, Menno P J de Winther, Rene R W J van der Hulst, Sofia Xanthoulea
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102994 (2014)
Macrophages play a crucial role in all stages of cutaneous wound healing responses and dysregulation of macrophage function can result in derailed wound repair. The phenotype of macrophages is influenced by the wound microenvironment and evolves duri
Externí odkaz:
https://doaj.org/article/bb4f07f96e634049827191034300ae28
Autor:
Jamie Kane, Winnie G. Vos, Laura A. Bosmans, Bram W. van Os, Myrthe den Toom, Sanne Hoeksema‐Hackmann, Denise Moen‐de Wit, Marion J. Gijbels, Linda Beckers, Aldo Grefhorst, Johannes H. M. Levels, Lily Jakulj, Marc G. Vervloet, Esther Lutgens, Etto C. Eringa
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Background Atherosclerosis is highly prevalent in people with chronic kidney disease (CKD), including those receiving peritoneal dialysis (PD). Although it is lifesaving, PD induces profound systemic inflammation, which may aggravate atherosclerosis.
Externí odkaz:
https://doaj.org/article/900228cfe42741e4b7f16aa3fbda51ad
Autor:
Martine Bot, Paul P Van Veldhoven, Saskia C A de Jager, Jason Johnson, Niels Nijstad, Peter J Van Santbrink, Marijke M Westra, Gerd Van Der Hoeven, Marion J Gijbels, Carsten Müller-Tidow, Georg Varga, Uwe J F Tietge, Johan Kuiper, Theo J C Van Berkel, Jerzy-Roch Nofer, Ilze Bot, Erik A L Biessen
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63360 (2013)
Altered sphingosine 1-phosphate (S1P) homeostasis and signaling is implicated in various inflammatory diseases including atherosclerosis. As S1P levels are tightly controlled by S1P lyase, we investigated the impact of hematopoietic S1P lyase (Sgpl1(
Externí odkaz:
https://doaj.org/article/1a0d95655b81411ea2e0c24d8f384462
Autor:
Veerle Bieghs, Patrick J Van Gorp, Kristiaan Wouters, Tim Hendrikx, Marion J Gijbels, Marc van Bilsen, Jaap Bakker, Christoph J Binder, Dieter Lütjohann, Bart Staels, Marten H Hofker, Ronit Shiri-Sverdlov
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30668 (2012)
Non-alcoholic steatohepatitis (NASH) involves steatosis combined with inflammation, which can progress into fibrosis and cirrhosis. Exploring the molecular mechanisms of NASH is highly dependent on the availability of animal models. Currently, the mo
Externí odkaz:
https://doaj.org/article/7cba33b418da4a33825a3a3df69bae0b
Autor:
Chris P. M. Reutelingsperger, Marion J. Gijbels, Henri Spronk, Rene Van Oerle, Roy Schrijver, Peter Ekhart, Sjef de Kimpe, Gerry A. F. Nicolaes
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1376 (2024)
Extracellular histones have been shown to act as DAMPs in a variety of inflammatory diseases. Moreover, they have the ability to induce cell death. In this study, we show that M6229, a low-anticoagulant fraction of unfractionated heparin (UFH), rescu
Externí odkaz:
https://doaj.org/article/d619560b95fb4294b9ca9688d8e839f3
Autor:
Danique J. I. Heuvelings, Anne G. W. E. Wintjens, Audrey C. H. M. Jongen, Maurits J. C. A. M. Gielen, Kaatje Lenaerts, Peter-Paul K. H. Fransen, Marion J. Gijbels, Geert C. van Almen, Patricia Y. W. Dankers, Ignace H. J. T. de Hingh, Nicole D. Bouvy
Publikováno v:
Life, Vol 13, Iss 10, p 2076 (2023)
The prognosis of colorectal cancer patients with peritoneal metastases is very poor. Intraperitoneal drug delivery systems, like supramolecular hydrogels, are being developed to improve local delivery and intraperitoneal residence time of a cytostati
Externí odkaz:
https://doaj.org/article/e8f4ef54c16b4657940277a093db5473
Autor:
Emiel P. C. van der Vorst, Sanne L. Maas, Kosta Theodorou, Linsey J. F. Peters, Han Jin, Timo Rademakers, Marion J. Gijbels, Mat Rousch, Yvonne Jansen, Christian Weber, Michael Lehrke, Corinna Lebherz, Daniela Yildiz, Andreas Ludwig, Jacob F. Bentzon, Erik A. L. Biessen, Marjo M. P. C. Donners
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionThe transmembrane protease A Disintegrin And Metalloproteinase 10 (ADAM10) displays a “pattern regulatory function,” by cleaving a range of membrane-bound proteins. In endothelium, it regulates barrier function, leukocyte recruitment
Externí odkaz:
https://doaj.org/article/f70375b98dbc4f308c54dc71482a5393
Autor:
Hong Liu, Jianhua Cao, Benjamin Balluff, Audrey C.H.M. Jongen, Marion J. Gijbels, Jarno Melenhorst, Ron M.A. Heeren, Nicole D. Bouvy
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss , Pp 35-41 (2021)
Background: Failure of fascial healing in the abdominal wall can result in incisional hernia, which is one of the most common complications after laparotomy. Understanding the molecular healing process of abdominal fascia may provide lipid markers of
Externí odkaz:
https://doaj.org/article/646a2486aac04d6f84b215f8ab89cba2