Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marion Hückel"'
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Abstract Background Fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA) are autonomously activated to maintain inflammation and joint destruction in co-transplantation models. To elucidate inducing mechanisms involved in
Externí odkaz:
https://doaj.org/article/b111b620c19a4e7398908e14f636aa4d
Autor:
Jürgen Bernhagen, Christina Pfirschke, Uta Schurigt, Rolf Bräuer, Marion Hückel, Tobias Janik, Ria Baumgrass, Ingo M. Irmler, Mieczyslaw Gajda
Publikováno v:
Arthritis and rheumatism. 58(10)
Objective Interactions of immune cells, such as activated T helper cells, with fibroblast-like synoviocytes (FLS) play a crucial role in the joint destruction during human rheumatoid arthritis (RA). This study was undertaken to investigate the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b70da158f44e29c6e455824aa66db25
https://pubmed.ncbi.nlm.nih.gov/18821693
https://pubmed.ncbi.nlm.nih.gov/18821693
Autor:
Marion, Hückel, Uta, Schurigt, Andreas H, Wagner, Renate, Stöckigt, Peter K, Petrow, Klaus, Thoss, Mieczyslaw, Gajda, Steffen, Henzgen, Markus, Hecker, Rolf, Bräuer
Publikováno v:
Arthritis Research & Therapy
The transcription factor STAT-1 (signal transducer and activator of transcription-1) plays a pivotal role in the expression of inflammatory gene products involved in the pathogenesis of arthritis such as various cytokines and the CD40/CD40 ligand (CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66e2ec05fcd2fc6a2a11095d2e42854b
https://pubmed.ncbi.nlm.nih.gov/16507120
https://pubmed.ncbi.nlm.nih.gov/16507120
Publikováno v:
Annals of the rheumatic diseases. 63(11)
Objective: To investigate the indirect effects of anti-CD4 treatment on the functions of macrophages (CD4 − in mice) in the acute and early chronic phase of mouse antigen induced arthritis (AIA). Methods: C57BL/6 mice with AIA were treated intraper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0833c35f60cf940292e41fdcad4dc4e3
https://pubmed.ncbi.nlm.nih.gov/15479897
https://pubmed.ncbi.nlm.nih.gov/15479897
Autor:
Marion Hückel, Rolf Bräuer, Gisela Segond von Banchet, Jonny Richter, Christina Rose, Hans-Georg Schaible
Publikováno v:
Arthritis Research & Therapy. 9:R6
Innervation of the joint with thinly myelinated and unmyelinated sensory nerve fibres is crucial for the occurrence of joint pain. During inflammation in the joint, sensory fibres show changes in the expression of receptors that are important for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a44f1b77d4a0ad886416c9f0adb56d
https://doi.org/10.1186/ar2112
https://doi.org/10.1186/ar2112
Autor:
Mieczyslaw Gajda, Markus Hecker, Marion Hückel, S. Henzgen, Rolf Bräuer, Peter K. Petrow, Andreas H. Wagner, Renate Stöckigt, Uta Schurigt, K. Thoss
Publikováno v:
Arthritis Research & Therapy. 8:R17
The transcription factor STAT-1 (signal transducer and activator of transcription-1) plays a pivotal role in the expression of inflammatory gene products involved in the pathogenesis of arthritis such as various cytokines and the CD40/CD40 ligand (CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8748770f3ecedf7d6fa9292dbb1c94ac
https://doi.org/10.1186/ar1869
https://doi.org/10.1186/ar1869
Autor:
Rolf Bräuer, Nadine Stopfel, Bernd Wiederanders, Marion Hückel, Uta Schurigt, Christina Pfirschke
Publikováno v:
Arthritis Research & Therapy. 7:R174
Cartilage and bone degradation, observed in human rheumatoid arthritis (RA), are caused by aberrant expression of proteinases, resulting in an imbalance of these degrading enzymes and their inhibitors. However, the role of the individual proteinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db5125c0f84a3262adf8b053fedd5a1f
https://doi.org/10.1186/ar1466
https://doi.org/10.1186/ar1466
Publikováno v:
Arthritis Research & Therapy. 6:59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5221ad6e9af6d0eacbac6c48992026ea
https://doi.org/10.1186/ar1395
https://doi.org/10.1186/ar1395