Magnetic resonance imaging under isoflurane anesthesia alters cortical cyclooxygenase-2 expression and glial cell morphology during sepsis-associated neurological dysfunction in rats

Autor: Jan Pieter Konsman, Marion Griton, Ibtihel Dhaya

Publikováno v: Animal Model Exp Med / Animal models and experimental medicine.
Animal Model Exp Med / Animal models and experimental medicine., [Hoboken, New Jersey] : John Wiley & Sons, Inc., [2018]-, 2021, 4, pp.249-260. ⟨10.1002/ame2.12167⟩
Animal Models and Experimental Medicine
Animal Models and Experimental Medicine, Vol 4, Iss 3, Pp 249-260 (2021)

Background Magnetic resonance imaging (MRI) of rodents combined with histology allows to determine what mechanisms underlie functional and structural brain changes during sepsis‐associated encephalopathy. However, the effects of MRI performed in is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfcd6575e166c6d35f78f987e2194af8
https://pubmed.ncbi.nlm.nih.gov/34557651

Experimental sepsis-associated encephalopathy is accompanied by altered cerebral blood perfusion and water diffusion and related to changes in cyclooxygenase-2 expression and glial cell morphology but not to blood-brain barrier breakdown

Autor: Renaud Nicolas, Bassem Hiba, Olivier Periot, Marion Griton, Jan Pieter Konsman, Ibtihel Dhaya, Gérard Raffard

Publikováno v: Brain, Behavior, and Immunity
Brain, Behavior, and Immunity, Elsevier, 2020, 83, pp.200-213. ⟨10.1016/j.bbi.2019.10.012⟩

Sepsis-associated encephalopathy (SAE) refers to brain dysfunction, including delirium, occurs during severe infection and is associated with development of post-traumatic stress disorder. SAE has been proposed to be related to reduced cerebral blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e4abaadb543e358a7ccd9a937776ed
https://hal.archives-ouvertes.fr/hal-03033791

Bacterial lipopolysaccharide-induced systemic inflammation alters perfusion of white matter-rich regions without altering flow in brain-irrigating arteries: Relationship to blood-brain barrier breakdown?

Autor: Marion Griton, Bassem Hiba, Mohamed Amri, Ibtihel Dhaya, Jan Pieter Konsman, Gérard Raffard

Publikováno v: Journal of Neuroimmunology
Journal of Neuroimmunology, Elsevier, 2018, 314, pp.67-80. ⟨10.1016/j.jneuroim.2017.11.009⟩

To better understand brain dysfunction during sepsis, cerebral arterial blood flow was assessed with Phase Contrast Magnetic Resonance Imaging, perfusion with Arterial Spin Labeling and structure with diffusion-weighted Magnetic Resonance Imaging in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c980f982f1cf78ba435dff885bb48bf0
https://pubmed.ncbi.nlm.nih.gov/29174195

Mini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room

Autor: Marion Griton, Hugues de Courson, R Lanchon, Bruno Pereira, Karine Nouette-Gaulain, Musa Sesay, Matthieu Biais, Guillaume Bardonneau

Publikováno v: Anesthesiology
Anesthesiology, 2017, 127 (3), pp.450-456. ⟨10.1097/ALN.0000000000001753⟩
Anesthesiology, Lippincott, Williams & Wilkins, 2017, 127 (3), pp.450-456. ⟨10.1097/ALN.0000000000001753⟩

Background Mini-fluid challenge of 100 ml colloids is thought to predict the effects of larger amounts of fluid (500 ml) in intensive care units. This study sought to determine whether a low quantity of crystalloid (50 and 100 ml) could predict the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9520ab8248c3c9a0bdb0bbfddd2b845b
https://doi.org/10.1097/ALN.0000000000001753

107. Bacterial lipopolysaccharide-induced systemic inflammation alters cerebral blood flow: Relationship to prostaglandin and NO production

Autor: Sylvain Miraux, Jean-Christophe Delpech, Jean-Michel Franconi, Marion Griton, Jan Pieter Konsman, Frédéric Villega

Publikováno v: Brain, Behavior, and Immunity. 32:e31

Delirium is a DSM-IVR diagnosis characterized by disturbed consciousness and changes in cognition over a short period of time. Cognition requires finely-regulated cerebral blood flow. Cerebral blood flow alterations may explain frequent delirium occu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f887eab3ca654093b6f4d52c84c71a8
https://doi.org/10.1016/j.bbi.2013.07.119