Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marion Griessl"'
Autor:
Marion Griessl, Angelique Renzaho, Kirsten Freitag, Christof K. Seckert, Matthias J. Reddehase, Niels A. W. Lemmermann
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Acute infection with murine cytomegalovirus (mCMV) is controlled by CD8+ T cells and develops into a state of latent infection, referred to as latency, which is defined by lifelong maintenance of viral genomes but absence of infectious virus in laten
Externí odkaz:
https://doaj.org/article/fbc693b8479447a69675a0b125a3be1c
Autor:
Joanne Trgovcich, Michelle Kincaid, Alicia Thomas, Marion Griessl, Peter Zimmerman, Varun Dwivedi, Valerie Bergdall, Paul Klenerman, Charles H Cook
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167097 (2016)
Cytomegalovirus (CMV) has been shown to induce large populations of CD8 T-effector memory cells that unlike central memory persist in large quantities following infection, a phenomenon commonly termed "memory inflation". Although murine models to dat
Externí odkaz:
https://doaj.org/article/e60f78e315ab4ba0876ac49a87c89392
Publikováno v:
Molecular Immunology. 150:9-10
Publikováno v:
Journal of virological methods. 301
Next Generation Sequencing allows for deep analysis of transcriptional activity in cells and tissues, however it is still a cost intensive method that demands well versed data handling. Reverse transcription quantitative PCR (RT-qPCR) is the most com
Autor:
Niels A. W. Lemmermann, Birgit Kühnapfel, Angélique Renzaho, Julia K Schmiedeke, Christof K. Seckert, Marion Griessl
Publikováno v:
Medical Microbiology and Immunology. 208:439-446
Roizman's definition of herpesviral latency, which applies also to cytomegaloviruses (CMVs), demands maintenance of reactivation-competent viral genomes after clearance of productive infection. It is more recent understanding that failure to complete
Autor:
Michał Nowicki, Hong Zhang, Franz Ricklefs, Michael Gutknecht, Charles Cobbs, Arun K. Rooj, Prajna Behera, Carmela Passaro, Hirotaka Ito, Sean E. Lawler, Rachel Zane, Lai Ding, Marion Griessl, E. Antonio Chiocca, C. David James, Mykola Zdioruk, Magdalena Skubal, Harald Krenzlin, Sharon Peled, Charles H. Cook, Korneel Grauwet, Viola Lorenz
Publikováno v:
Journal of Clinical Investigation. 129:1671-1683
Cytomegalovirus (CMV) has been implicated in glioblastoma (GBM); however, a mechanistic connection in vivo has not been established. The purpose of this study is to characterize the effects of murine CMV (MCMV) on GBM growth in murine models. Syngene
Autor:
Niels A. W. Lemmermann, Angélique Renzaho, Kirsten Freitag, Matthias J. Reddehase, Marion Griessl, Christof K. Seckert
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Acute infection with murine cytomegalovirus (mCMV) is controlled by CD8+ T cells and develops into a state of latent infection, referred to as latency, which is defined by lifelong maintenance of viral genomes but absence of infectious virus in laten
Publikováno v:
Journal of Virological Methods
Reverse transcription quantitative PCR (RT-qPCR) is the most commonly used method to evaluate gene expression. Reliable qPCR results are highly dependent on accurate normalization using suitable reference genes. We investigated expression of commonly
Autor:
Michael Gutknecht, Sara Byrd, Varun Dwivedi, Charles H. Cook, Marion Griessl, Sara A. Mansfield, Joanne Trgovcich
Publikováno v:
Journal of Medical Virology. 88:1408-1416
Roughly 1/3rd of immune competent patients will reactivate latent cytomegalovirus (CMV) during critical illness. There are no standard methods to detect reactivation, and some investigators have postulated that presence of DNA in BAL fluid is indicat
Autor:
Alicia Thomas, Peter D. Zimmerman, Paul Klenerman, Marion Griessl, Joanne Trgovcich, Valerie K. Bergdall, Michelle Kincaid, Varun Dwivedi, Charles H. Cook
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0167097 (2016)
PLoS ONE, Vol 11, Iss 11, p e0167097 (2016)
Cytomegalovirus (CMV) has been shown to induce large populations of CD8 T-effector memory cells that unlike central memory persist in large quantities following infection, a phenomenon commonly termed “memory inflation”. Although murine models to