Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marion Goldeck"'
Autor:
Charlotte Lässig, Sarah Matheisl, Konstantin MJ Sparrer, Carina C de Oliveira Mann, Manuela Moldt, Jenish R Patel, Marion Goldeck, Gunther Hartmann, Adolfo García-Sastre, Veit Hornung, Karl‐Klaus Conzelmann, Roland Beckmann, Karl-Peter Hopfner
Publikováno v:
eLife, Vol 5 (2016)
Externí odkaz:
https://doaj.org/article/d2557d7a40c040cabde3ba3a39064587
Autor:
Charlotte Lässig, Sarah Matheisl, Konstantin MJ Sparrer, Carina C de Oliveira Mann, Manuela Moldt, Jenish R Patel, Marion Goldeck, Gunther Hartmann, Adolfo García-Sastre, Veit Hornung, Karl-Klaus Conzelmann, Roland Beckmann, Karl-Peter Hopfner
Publikováno v:
eLife, Vol 4 (2015)
The cytosolic antiviral innate immune sensor RIG-I distinguishes 5′ tri- or diphosphate containing viral double-stranded (ds) RNA from self-RNA by an incompletely understood mechanism that involves ATP hydrolysis by RIG-I's RNA translocase domain.
Externí odkaz:
https://doaj.org/article/2e811ce05e7446f6a397f6eb374e63a6
Autor:
Walter Kuba, Barbara Sohr, Patrick Keppel, Dennis Svatunek, Viktoria Humhal, Berthold Stöger, Marion Goldeck, Jonathan C. T. Carlson, Hannes Mikula
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany).
Modified trans-cyclooctenes (TCO) are capable of highly efficient molecular manipulations in biological environments, driven by the bioorthogonal reaction with tetrazines (Tz). The development of click-cleavable TCO has fueled the field of in vivo ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8e4d104fa341200d06cc140f67cdae
https://pubmed.ncbi.nlm.nih.gov/36250260
https://pubmed.ncbi.nlm.nih.gov/36250260
Autor:
Patrick Keppel, Barbara Sohr, Walter Kuba, Marion Goldeck, Philipp Skrinjar, Jonathan C. T. Carlson, Hannes Mikula
Publikováno v:
ChemBioChem. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab04e4c938f6c05edbad3b65a30afac
https://doi.org/10.1002/cbic.202200542
https://doi.org/10.1002/cbic.202200542
Autor:
Patrick Keppel, Barbara Sohr, Walter Kuba, Marion Goldeck, Philipp Skrinjar, Jonathan C. T. Carlson, Hannes Mikula
Publikováno v:
ChemBioChem. 23
Bond-cleavage reactions triggered by bioorthogonal tetrazine ligation have emerged as strategies to chemically control the function of (bio)molecules and achieve activation of prodrugs in living systems. While most of these approaches make use of cag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b184f6d6124647732928777b19d67a47
https://doi.org/10.1002/cbic.202200363
https://doi.org/10.1002/cbic.202200363
Autor:
Marion Goldeck, Aiswarya Gopal, Michael F. Jantsch, Hamid Reza Mansouri Khosravi, Vinod Rajendra, Cornelia Vesely
Publikováno v:
American journal of physiology. Cell physiology. 323(5)
Adenosine deaminases acting on RNAs convert adenosines (A) to inosines (I) in structured or double-stranded RNAs. In mammals, this process is widespread. In the human transcriptome, more than a million different sites have been identified that underg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5a9a7aaf0cbe3649f5cd3e466ef4fa
https://pubmed.ncbi.nlm.nih.gov/36036447
https://pubmed.ncbi.nlm.nih.gov/36036447
Autor:
Thomas Zillinger, Christine Schuberth-Wagner, Veit Hornung, Steven Wolter, Ann Kristin Bruder, Marion Goldeck, Martin Schlee, Jonathan L. Schmid-Burgk, Gunther Hartmann, Christoph Coch, Winfried Barchet, Anna-Maria Herzner, Beate M. Kümmerer, Janos Ludwig, Jan-Philip Stümpel, Andreas Roth, Christian Drosten, Romy Kerber, Tobias Schmidt, Eva Bartok
Publikováno v:
Immunity. 43:41-51
SummaryThe cytosolic helicase retinoic acid-inducible gene-I (RIG-I) initiates immune responses to most RNA viruses by detecting viral 5′-triphosphorylated RNA (pppRNA). Although endogenous mRNA is also 5′-triphosphorylated, backbone modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26eb15fa82a89e8e071a270bb782f5df
https://doi.org/10.1016/j.immuni.2015.06.015
https://doi.org/10.1016/j.immuni.2015.06.015
Autor:
Tsutomu Fujimura, Christine Schuberth, Andrea J. Pruijssers, Jan Rehwinkel, Caetano Reis e Sousa, Delphine Goubau, Jason A. Iskarpatyoti, Martin Schlee, Gunther Hartmann, Thomas Zillinger, Terence S. Dermody, Annemarthe G. van der Veen, Safia Deddouche, Janos Ludwig, Marion Goldeck, Winfried Barchet
Publikováno v:
Nature
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Mammalian cells possess mechanisms to detect and defend themselves from invading viruses. In the cytosol, the RIG-I-like receptors (RLRs), RIG-I (retinoic acid-inducible gene I; encoded by DDX58) and MDA5 (melanoma differentiation-associated gene 5;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c853a3df25546877aa6d6695f04b5683
https://doi.org/10.1038/nature13590
https://doi.org/10.1038/nature13590
Publikováno v:
Angewandte Chemie. 126:4782-4786
A novel solid-phase synthesis and purification strategy for 5'-triphosphate oligonucleotides by using lipophilic tagging of the triphosphate moiety is reported. This is based on triphosphate synthesis with 5'-O-cyclotriphosphate intermediates, whereb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6b211fb02d94bd1849ec6b78c3ff38
https://doi.org/10.1002/ange.201400672
https://doi.org/10.1002/ange.201400672
Autor:
Taner Cavlar, Veit Hornung, Gregor Witte, Karl-Peter Hopfner, Ingo Röhl, Marion Goldeck, Tobias Deimling, Andrea Ablasser, Janos Ludwig
Publikováno v:
Nature. 498:380-384
Detection of cytoplasmic DNA represents one of the most fundamental mechanisms of the innate immune system to sense the presence of microbial pathogens1. Moreover, erroneous detection of endogenous DNA by the same sensing mechanisms has an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace61c808ae679765ab77374bbeac543
https://doi.org/10.1038/nature12306
https://doi.org/10.1038/nature12306