Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marion Doladilhe"'
Autor:
James Okoh, Jacqunae Mays, Alexandre Bacq, Juan A. Oses-Prieto, Stefka Tyanova, Chien-Ju Chen, Khalel Imanbeyev, Marion Doladilhe, Hongyi Zhou, Paymaan Jafar-Nejad, Alma Burlingame, Jeffrey Noebels, Stephanie Baulac, Mauro Costa-Mattioli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Epilepsy is a neurological disorder that poses a major threat to public health. Hyperactivation of mTOR complex 1 (mTORC1) is believed to lead to abnormal network rhythmicity associated with epilepsy, and its inhibition is proposed to provid
Externí odkaz:
https://doaj.org/article/090b16c003544d13bd1df6abfc9cb943
Autor:
Marion Doladilhe, Vincent Dive, Olivier Lequin, Pierrick Bruyat, Monika Kaminska, Dimitris Georgiadis, Carole Fruchart Gaillard, Mélissa De Souza, Robert Thai, Evelyne Cassar-Lajeunesse, Carole Malgorn, Laurent Devel, Andrzej Galat, Fabrice Beau, Sarah Bregant, Isabelle Correia
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2021, 60 (33), pp.18272-18279. ⟨10.1002/anie.202106117⟩
Angewandte Chemie International Edition, 2021, 60 (33), pp.18272-18279. ⟨10.1002/anie.202106117⟩
International audience; Activity-based probes enable discrimination between the active enzyme and its inactive or inactivated counterparts. Since metalloproteases catalysis is non-covalent, activity-based probes targeting them have been systematicall
Autor:
Jean-Jacques Panthier, Caroline Manet, Laurine Conquet, Anavaj Sakuntabhai, Etienne Simon-Loriere, Xavier Montagutelli, David Hardy, Matthieu Prot, Marie Flamand, Grégory Jouvion
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2020, 94 (3), ⟨10.1128/JVI.01034-19⟩
Journal of Virology, 2020, 94 (3), ⟨10.1128/JVI.01034-19⟩
Journal of Virology, American Society for Microbiology, 2020, 94 (3), ⟨10.1128/JVI.01034-19⟩
Journal of Virology, 2020, 94 (3), ⟨10.1128/JVI.01034-19⟩
International audience; The explosive spread of Zika virus (ZIKV) has been associated with major variations in severe disease and congenital afflictions among infected populations, suggesting an influence of host genes. We investigated how genome-wid