Data from Danger Signaling Protein HMGB1 Induces a Distinct Form of Cell Death Accompanied by Formation of Giant Mitochondria

Autor: Wilfried Roth, Peter Schirmacher, Otmar D. Wiestler, Hans-Walter Zentgraf, Tim Kees, Julie George, Alexander N.R. Weber, Anne Fassl, Marion Bergmann, Jürgen Kopitz, Martina Keith, Georg Gdynia

Cells dying by necrosis release the high-mobility group box 1 (HMGB1) protein, which has immunostimulatory effects. However, little is known about the direct actions of extracellular HMGB1 protein on cancer cells. Here, we show that recombinant human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69027ec5b6b45d3d73c9e590fe146049
https://doi.org/10.1158/0008-5472.c.6500850.v1

Supplementary Figures 1-16 from Danger Signaling Protein HMGB1 Induces a Distinct Form of Cell Death Accompanied by Formation of Giant Mitochondria

Autor: Wilfried Roth, Peter Schirmacher, Otmar D. Wiestler, Hans-Walter Zentgraf, Tim Kees, Julie George, Alexander N.R. Weber, Anne Fassl, Marion Bergmann, Jürgen Kopitz, Martina Keith, Georg Gdynia

Supplementary Figures 1-16 from Danger Signaling Protein HMGB1 Induces a Distinct Form of Cell Death Accompanied by Formation of Giant Mitochondria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e140e9b095d8b7d42fd269fcc67351
https://doi.org/10.1158/0008-5472.22384335

Chromosomal gains and losses in human papillomavirus-associated neoplasia of the lower genital tract – A systematic review and meta-analysis

Autor: Renske D.M. Steenbergen, Justo Lorenzo Bermejo, Lorenz K. Thomas, Magnus von Knebel Doeberitz, Svetlana Vinokurova, Katrin Jensen, Miriam Reuschenbach, Marion Bergmann, Mariska Bierkens

Publikováno v: European Journal of Cancer, 50(1), 85-98. Pergamon
Thomas, L K, Bermejo, J L, Vinokurova, S, Jensen, K, Bierkens, M, Steenbergen, R D M, Bergmann, M, Doeberitz, M & Reuschenbach, M 2014, ' Chromosomal gains and losses in human papillomavirus-associated neoplasia of the lower genital tract-A systematic review and meta-analysis ', European Journal of Cancer, vol. 50, no. 1, pp. 85-98 . https://doi.org/10.1016/j.ejca.2013.08.022

Background Overexpression of the human papillomavirus (HPV) oncogenes E6 and E7 is necessary for the development of distinct lower genital tract cancers. However, secondary cellular genomic alterations are mandatory to promote progression of HPV-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0cbb0843e5f4adb4f4255d2d6e3ec00
https://doi.org/10.1016/j.ejca.2013.08.022

Danger Signaling Protein HMGB1 Induces a Distinct Form of Cell Death Accompanied by Formation of Giant Mitochondria

Autor: Marion Bergmann, Martina Keith, Julie George, Jürgen Kopitz, Anne Fassl, Otmar D. Wiestler, Georg Gdynia, Hans Walter Zentgraf, Tim Kees, Alexander N.R. Weber, Wilfried Roth, Peter Schirmacher

Publikováno v: Cancer Research. 70:8558-8568

Cells dying by necrosis release the high-mobility group box 1 (HMGB1) protein, which has immunostimulatory effects. However, little is known about the direct actions of extracellular HMGB1 protein on cancer cells. Here, we show that recombinant human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594b4e80b1f72905eb5286e482f7927f
https://doi.org/10.1158/0008-5472.can-10-0204

Isolation of intact lysosomes from human RPE cells and effects of A2-E on the integrity of the lysosomal and other cellular membranes

Autor: J. Kopitz, Marion Bergmann, Frank G. Holz, F. Schütt

Publikováno v: Graefe's Archive for Clinical and Experimental Ophthalmology. 240:983-988

Background. Accumulation of lipofuscin in RPE cells occurs with age and in association with various retinal diseases. Lipofuscin and its major retinoid compound and fluorophore A2-E interfere with the cellular metabolism of RPE cells in various ways.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac990689eaaf59efcd5d1064249f5295
https://doi.org/10.1007/s00417-002-0558-8