Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation

Autor: Eline Lemerle, Jeanne Lainé, Marion Benoist, Gilles Moulay, Anne Bigot, Clémence Labasse, Angéline Madelaine, Alexis Canette, Perrine Aubin, Jean-Michel Vallat, Norma B Romero, Marc Bitoun, Vincent Mouly, Isabelle Marty, Bruno Cadot, Laura Picas, Stéphane Vassilopoulos

Publikováno v: eLife, Vol 12 (2023)

Excitation-contraction coupling requires a highly specialized membrane structure, the triad, composed of a plasma membrane invagination, the T-tubule, surrounded by two sarcoplasmic reticulum terminal cisternae. Although the precise mechanisms govern

Externí odkaz: https://doaj.org/article/30988e26f18d4cc88809cbec0d185677

Hippocampal Dendritic Spines Are Segregated Depending on Their Actin Polymerization

Autor: Nuria Domínguez-Iturza, María Calvo, Marion Benoist, José Antonio Esteban, Miguel Morales

Publikováno v: Neural Plasticity, Vol 2016 (2016)

Dendritic spines are mushroom-shaped protrusions of the postsynaptic membrane. Spines receive the majority of glutamatergic synaptic inputs. Their morphology, dynamics, and density have been related to synaptic plasticity and learning. The main deter

Externí odkaz: https://doaj.org/article/8ba41aff6d774f9d9a4184c351ed62c2

Next generation cytogenetics: genome-imaging enables comprehensive structural variant detection for 100 constitutional chromosomal aberrations in 85 samples

Autor: Tuomo Mantere, Laila El Khattabi, Céline Pebrel-Richard, Alexander Hoischen, Marian Stevens-Kroef, Susan Vermeulen, Caroline Schluth-Bolard, Tony Yammine, Michiel Oorsprong, Marion Benoist, Aziza Lebbar, Dominique Smeets, Kornelia Neveling, Ronald van Beek, Jean Michel Dupont, Damien Sanlaville, Guillaume van der Zande, Marc Pauper, Ellen Kater-Baats, Daniel Olde-Weghuis, Imane Baatout, Wed Majdali

Chromosomal aberrations and structural variations are a major cause of human genetic diseases. Their detection in clinical routine still relies on standard cytogenetics, karyotyping and CNV-microarrays, in spite of the low resolution of the first one

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3de8e5628ea67fb1ec3cfa08a4a03583
https://doi.org/10.1101/2020.07.15.205245

MAP1B light chain modulates synaptic transmission via AMPA receptor intracellular trapping

Autor: José A. Esteban, Yolanda Gutiérrez, Argentina Lario, Marion Benoist, Rocío Palenzuela, Jonathan E. Draffin

Publikováno v: DDFV: Repositorio Institucional de la Universidad Francisco de Vitoria
Universidad Francisco de Vitoria
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname
Digital.CSIC. Repositorio Institucional del CSIC

The regulated transport of AMPA-type glutamate receptors (AMPARs) to the synaptic membrane is a key mechanism to determine the strength of excitatory synaptic transmission in the brain. In this work, we uncovered a new role for the microtubule-associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dc25e991d26fa608cf02aa34a46957
http://hdl.handle.net/10261/166198

Targeting of Proteins of the Striatin Family to Dendritic Spines: Role of the Coiled-Coil Domain

Autor: Laure Fronzaroli-Molinieres, Jean-Pierre Kessler, Tatiana V. Rakitina, Francis Castets, Yannick Bailly, Bénédicte Dargent, Marion Benoist, Stéphane Gaillard

Publikováno v: Traffic. 7:74-84

Striatin, SG2NA and zinedin, the three mammalian members of the striatin family are multimodular WD-repeat, calmodulin and calveolin-binding proteins. These scaffolding proteins, involved in both signaling and trafficking, are highly expressed in neu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ee5a6fdaab2a3c2e61ef00c68e23445
https://doi.org/10.1111/j.1600-0854.2005.00363.x