Výsledky vyhledávání - "Marion Baudard"

Targeting NF-κB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

Autor: Karène Mahtouk, Thierry Rème, Angela Romanelli, Dirk Hose, Michel Jourdan, Jean-François Rossi, Bernard Klein, Marion Baudard, Nicolas Robert, Jérôme Moreaux, Michel Dreano, Matthieu Abouladze, John De Vos, Hartmut Goldschmidt

Publikováno v: British Journal of Haematology
British Journal of Haematology, Wiley, 2007, 138 (2), pp.160-8. ⟨10.1111/j.1365-2141.2007.06629.x⟩

The pathophysiologic basis for multiple myeloma (MM) has been attributed to the dysregulation of various paracrine or autocrine growth factor loops and to perturbations in several signal transduction pathways including IkappaB kinase/nuclear factor-k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc45a8e1b734d9677f5527cf613765d
https://doi.org/10.1111/j.1365-2141.2007.06629.x

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Functional Regulatory T Cells Are Collected in Stem Cell Autografts by Mobilization with High-Dose Cyclophosphamide and Granulocyte Colony-Stimulating Factor

Autor: Bernard Klein, Marion Baudard, Philippe Quittet, Maud Condomines, Jean-François Rossi, Jean-François Schved, Zhao-Yang Lu, Ernesto Lopez, Pascal Latry, L Nadal, Karin Tarte, Christophe Duperray, Guilhem Requirand

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2006, 176 (11), pp.6631-9

High-dose cyclophosphamide (Cy) and G-CSF are widely used to mobilize hemopoietic stem cells for treating patients with high-dose chemotherapy and autologous stem cell transplantation (ASCT). Because lymphocyte count in the graft collected after Cy-G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c667fc6cc543a77e15e1b4a3aa0415ed
https://doi.org/10.4049/jimmunol.176.11.6631

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JC-1: a very sensitive fluorescent probe to test Pgp activity in adult acute myeloid leukemia

Autor: Marion Baudard, O. Legrand, Jean-Yves Perrot, Ghislaine Simonin, Jean-Pierre Marie

Publikováno v: Blood. 97:502-508

One of the best-characterized resistance mechanisms in acute myeloid leukemia (AML) is the drug extrusion mediated by P-glycoprotein (Pgp). Recently the results of workshops organized by several groups concluded that accurate measurement of low activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbef4a2ce0a0ccc734dc10857e06c26
https://doi.org/10.1182/blood.v97.2.502

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The immunophenotype of 177 adults with acute myeloid leukemia: proposal of a prognostic score

Autor: Ollivier Legrand, Nicole Casadevall, Régine Lautier, Marion Baudard, Annie Cordier, Ghislaine Simonin, Jean-Yves Perrot, Zittoun R, Jean-Pierre Marie

Publikováno v: Blood. 96:870-877

In acute myeloid leukemia (AML) patients, a variety of clinical and biologic parameters, including phenotype, have been examined for potential value in predicting treatment response and survival. The European Group for the Immunological Classificatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547f791462e7d54ed93bfe3f7af34116
https://doi.org/10.1182/blood.v96.3.870.015k16_870_877

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Has the prognosis of adult patients with acute myeloid leukemia improved over years? A single institution experience of 784 consecutive patients over a 16-year period

Autor: A Beauchamp-Nicoud, Blanc Cm, Jean-Pierre Marie, Bernard Rio, Alain Delmer, Marion Baudard, Zittoun R

Publikováno v: Leukemia. 13:1481-1490

We reviewed the reports of 784 consecutive patients admitted to our department for newly diagnosed acute myeloid leukemia (AML) over a 16-year period. Median, 5-year and 10-year overall survivals were 9. 5 months, 17.3% and 11.7% respectively. Induct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad2091085180ee692271056a529c9e9
https://doi.org/10.1038/sj.leu.2401544

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Smoldering Acute Myelogenous Leukemia in the Elderly

Autor: Jean-Pierre Marie, Ollivier Legrand, Robert Zittoun, Marion Baudard

Publikováno v: Leukemia & Lymphoma. 34:561-567

Out of 75 consecutive elderly AML patients who did not receive anti-leukemic treatment (52 pts) or failed to respond to differentiating agent (23 pts), 6 patients had survivals of 13.2 to 98 months with treatment restricted to supportive care. This c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589b697d2a15381c91c2ae92a7749e5c
https://doi.org/10.3109/10428199909058484

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Adult biphenotypic acute leukaemia: an entity with poor prognosis which is related to unfavourable cytogenetics and P‐glycoprotein over‐expression

Autor: Franck Viguié, Jean-Pierre Marie, Ghislaine Simonin, Ollivier Legrand, Robert Zittoun, M. Cadiou, Marion Baudard, Jean-Yves Perrot, Claude Blanc, Sylvie Ramond

Publikováno v: British Journal of Haematology. 100:147-155

Biphenotypic acute leukaemia (BAL) patients represented 8% of the 287 de novo consecutive adult acute leukaemias (23 BAL, 230 acute myeloid leukaemia (AML) and 34 acute lymphoblastic leukaemia (ALL)) referred to our department during the last 4-year

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c8a7198a80718b3a75fbdedff4743a
https://doi.org/10.1046/j.1365-2141.1998.00523.x

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Expression of the Human Multidrug Resistance and Glucocerebrosidase cDNAs from Adeno-Associated Vectors: Efficient Promoter Activity of AAV Sequences andIn VivoDelivery via Liposomes

Autor: William G. Kearns, Alain R. Thierry, Marion Baudard, Josep M. Aran, Terence R. Flotte, Myung-Geol Pang, Ira Pastan, Michael M. Gottesman

Publikováno v: Human Gene Therapy. 7:1309-1322

Recombinant adeno-associated viruses (rAAV) are attractive tools for gene therapy. We designed plasmids in which the human multidrug resistance gene (hMDR1) cDNA was placed downstream from portions of the 5' end of AAV including either a 234-bp casse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c8a81e12e1ede92a57e0805313fc2c
https://doi.org/10.1089/hum.1996.7.11-1309

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A phase II study of the cancer vaccine TG4010 alone and in combination with cytokines in patients with metastatic renal clear-cell carcinoma: clinical and immunological findings

Autor: François Ringeisen, Marie-Aude Lefrère-Belda, Marion Baudard, Michel Azizi, Wolf H. Fridman, Claude Linassier, Jean-Marc Limacher, Bruce Acres, Jean-Pascal Machiels, Benoit Beuselinck, Olivier Rixe, Thierry Velu, Eugeniu Banu, Eric Tartour, Stéphane Oudard

Publikováno v: Cancer immunology, immunotherapy : CII. 60(2)

MUC1 over-expression in renal clear-cell carcinoma (RCC) is associated with poor prognosis. This phase II study determined the efficacy and tolerability of TG4010, a cancer vaccine based on a modified vaccinia virus expressing MUC1 and interleukin-2,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5e58f7a8d480793f2177864a17c6bf
https://pubmed.ncbi.nlm.nih.gov/21069322

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