Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Marion, Kennedy"'
Autor:
Barbara Mair, Jelena Tomic, Sanna N. Masud, Peter Tonge, Alexander Weiss, Matej Usaj, Amy Hin Yan Tong, Jamie J. Kwan, Kevin R. Brown, Emily Titus, Michael Atkins, Katherine S.K. Chan, Lise Munsie, Andrea Habsid, Hong Han, Marion Kennedy, Brenda Cohen, Gordon Keller, Jason Moffat
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 599-615.e12 (2019)
Summary: Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms, a critical first step involves systemati
Externí odkaz:
https://doaj.org/article/b48e7be0191349729bde89c8056e0021
Autor:
Marion Kennedy, Geneve Awong, Christopher M. Sturgeon, Andrea Ditadi, Ross LaMotte-Mohs, Juan Carlos Zúñiga-Pflücker, Gordon Keller
Publikováno v:
Cell Reports, Vol 2, Iss 6, Pp 1722-1735 (2012)
The efficient generation of hematopoietic stem cells from human pluripotent stem cells is dependent on the appropriate specification of the definitive hematopoietic program during differentiation. In this study, we used T lymphocyte potential to trac
Externí odkaz:
https://doaj.org/article/a65871c2a6f344ad99e64ff48f4cf836
Autor:
Michael Atkins, Marion Kennedy, Kevin R. Brown, Sanna Masud, Katherine S. K. Chan, Lise Munsie, Matej Usaj, Gordon Keller, Brenda Cohen, Amy Hin Yan Tong, Barbara Mair, Alexander Weiss, Emily Titus, Andrea Habsid, Jamie J. Kwan, Jason Moffat, Hong Han, Peter Tonge, Jelena Tomic
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 599-615.e12 (2019)
Summary: Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms, a critical first step involves systemati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf93e0593d796de02cd0643f22f2323
https://pubmed.ncbi.nlm.nih.gov/30970261
https://pubmed.ncbi.nlm.nih.gov/30970261
Autor:
Amanda D. Yzaguirre, Andrea Ditadi, Gordon Keller, Xin Cheng, Christopher M. Sturgeon, Elizabeth Ng, Edouard G. Stanley, Geneve Awong, Lisa Azzola, Paul Gadue, Marion Kennedy, Deborah L. French, Joanna Tober, Nancy A. Speck, Andrew G. Elefanty
Publikováno v:
Nature cell biology
The generation of haematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) will depend on the accurate recapitulation of embryonic haematopoiesis. In the early embryo, HSCs develop from the haemogenic endothelium (HE) and are specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d01820e993316ab09cd465d16744a13
https://doi.org/10.1038/ncb3161
https://doi.org/10.1038/ncb3161
Autor:
Juan Carlos Zúñiga-Pflücker, Marion Kennedy, Christopher M. Sturgeon, Gordon Keller, Geneve Awong, Ross LaMotte-Mohs, Andrea Ditadi
Publikováno v:
Cell Reports, Vol 2, Iss 6, Pp 1722-1735 (2012)
SummaryThe efficient generation of hematopoietic stem cells from human pluripotent stem cells is dependent on the appropriate specification of the definitive hematopoietic program during differentiation. In this study, we used T lymphocyte potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7812c74cbf5ac16c2e2abd7aa8c09aef
http://www.sciencedirect.com/science/article/pii/S2211124712003841
http://www.sciencedirect.com/science/article/pii/S2211124712003841
Autor:
Markus Landthaler, Saghi Ghaffari, Nai Wen Chi, Jie Su, Gordon Keller, Xin Zhang, Rani S. Sellers, Pauline Rimmele, Sathish Kumar Mungamuri, Marion Kennedy, Thomas Tuschl, Tsung Yin J. Yeh, Ihor R. Lemischka, Safak Yalcin, Dung Fang Lee, Seung Min Lee
Publikováno v:
Nature Cell Biology. 13:1092-1099
Pluripotency of embryonic stem cells (ESCs) is defined by their ability to differentiate into three germ layers and derivative cell types1-3 and is established by an interactive network of proteins including OCT4 (also known as POU5F1; ref. 4), NANOG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc99f49787a30c96cc3987fe0bed530
https://doi.org/10.1038/ncb2293
https://doi.org/10.1038/ncb2293
Autor:
In-Hyun Park, Aline Bozec, Agamemnon E. Grigoriadis, Erwin F. Wagner, Gudrun Stenbeck, Marion Kennedy, Gordon Keller, Fiona K Brunton
Publikováno v:
Blood. 115:2769-2776
The directed differentiation of human pluripotent stem cells offers the unique opportunity to generate a broad spectrum of human cell types and tissues for transplantation, drug discovery, and studying disease mechanisms. Here, we report the stepwise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a08e2e953458ce914d46c5745ae144
https://doi.org/10.1182/blood-2009-07-234690
https://doi.org/10.1182/blood-2009-07-234690
Autor:
Kristina Bonham, Loren J. Field, Els Henckaerts, Eric Adler, Geoffrey W. Abbott, Marion Kennedy, R. Michael Linden, Mark H. Soonpaa, Lei Yang, Torsten K. Roepke, Gordon Keller, Steven J. Kattman
Publikováno v:
Nature. 453:524-528
The functional heart is comprised of distinct mesoderm-derived lineages including cardiomyocytes, endothelial cells and vascular smooth muscle cells. Studies in the mouse embryo and the mouse embryonic stem cell differentiation model have provided ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b63bb1162948bbfc71b24624621b12
https://doi.org/10.1038/nature06894
https://doi.org/10.1038/nature06894
Autor:
Silvia Giliani, Anne Marie Comeau, Itai M. Pessach, Juan Carlos Zúñiga-Pflücker, David G. Schatz, Carmen Dominguez-Brauer, Luigi D. Notarangelo, Yuhang Zhang, Barry P. Sleckman, Kerstin Felgentreff, Gordon Keller, Marion Kennedy, Frederic D. Bushman, Geneve Awong, Waleed Al-Herz, Francesca A. Ververs, Likun Du, Yu Nee Lee, Andrea L. Bredemeyer, Jared H. Rowe, Patrick M. Brauer, Lisa Ott de Bruin, Erik L. Clarke
Publikováno v:
Blood. 128(6)
Primary immunodeficiency diseases comprise a group of heterogeneous genetic defects that affect immune system development and/or function. Here we use in vitro differentiation of human induced pluripotent stem cells (iPSCs) generated from patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190c18a8f11f4b0f76a37ba08940676b
https://pubmed.ncbi.nlm.nih.gov/27516425
https://pubmed.ncbi.nlm.nih.gov/27516425
Publikováno v:
Europe PubMed Central
The in vitro differentiation of embryonic stem (ES) cells provides a powerful approach for studying the earliest events involved in the commitment of the hematopoietic and endothelial lineages. Using this model system, we have identified a precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfb0e41aa565691810c22d7859792bb
https://doi.org/10.1111/j.1749-6632.2001.tb03578.x
https://doi.org/10.1111/j.1749-6632.2001.tb03578.x