Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Marion, Espéli"'
Autor:
David Fandrei, Tony Huynh, Marie Sébert, Lorea Aguinaga, Valeria Bisio, Rathana Kim, Emmanuelle Clappier, Marion Espéli, Karl Balabanian, Hélène Moins-Teisserenc, Antoine Toubert, Nicolas Dulphy, Pierre Fenaux, Lionel Adès, Lin-Pierre Zhao
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/88c7fccd841544b4a98e51be7f98109a
Autor:
Adrienne Anginot, Julie Nguyen, Zeina Abou Nader, Vincent Rondeau, Amélie Bonaud, Maria Kalogeraki, Antoine Boutin, Julia P. Lemos, Valeria Bisio, Joyce Koenen, Lea Hanna Doumit Sakr, Amandine Picart, Amélie Coudert, Sylvain Provot, Nicolas Dulphy, Michel Aurrand-Lions, Stéphane J. C. Mancini, Gwendal Lazennec, David H. McDermott, Fabien Guidez, Claudine Blin-Wakkach, Philip M. Murphy, Martine Cohen-Solal, Marion Espéli, Matthieu Rouleau, Karl Balabanian
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract WHIM Syndrome is a rare immunodeficiency caused by gain-of-function CXCR4 mutations. Here we report a decrease in bone mineral density in 25% of WHIM patients and bone defects leading to osteoporosis in a WHIM mouse model. Imbalanced bone ti
Externí odkaz:
https://doaj.org/article/71e743108c284ff4a7d508b10f487735
Autor:
Pierre-Edouard Debureaux, Nathalie Forgeard, Dikelele Elessa, Stéphanie Harel, Laurent Frenzel, Bruno Royer, Alexis Talbot, Sylvain Choquet, Frederic Davi, Florence Nguyen-Khac, Wendy Cuccuini, Morgane Cheminant, Clotilde Bravetti, Gregory Lazarian, Sophie Kaltenbach, Olivier Hermine, Damien Roos-Weil, Marion Espéli, Karl Balabanian, Bertrand Arnulf
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/ab84babbb7c54bb5a1d146187514f7eb
Autor:
Laurent Beuret, Simon-Pierre Fortier-Beaulieu, Vincent Rondeau, Sophie Roy, Nicolas Houde, Karl Balabanian, Marion Espéli, Jean Charron
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Several studies have established the crucial role of the extracellular signal–regulated kinase (ERK)/mitogen-activated protein kinase pathway in hematopoietic cell proliferation and differentiation. MEK1 and MEK2 phosphorylate and activate ERK1 and
Externí odkaz:
https://doaj.org/article/551a2b37afce409691d6b39eaab6cea2
Autor:
Catherine Ouk, Lilian Roland, Nathalie Gachard, Stéphanie Poulain, Christelle Oblet, David Rizzo, Alexis Saintamand, Quentin Lemasson, Claire Carrion, Morgane Thomas, Karl Balabanian, Marion Espéli, Marie Parrens, Isabelle Soubeyran, Mélanie Boulin, Nathalie Faumont, Jean Feuillard, Christelle Vincent-Fabert
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Activating mutations of MYD88 (MYD88L265P being the far most frequent) are found in most cases of Waldenström macroglobulinemia (WM) as well as in various aggressive B-cell lymphoma entities with features of plasma cell (PC) differentiation, such as
Externí odkaz:
https://doaj.org/article/6ae2c3b7bfc345f6b7a93a374d068805
Autor:
Marion Espéli, Rachael Bashford-Rogers, John M. Sowerby, Nagham Alouche, Limy Wong, Alice E. Denton, Michelle A. Linterman, Kenneth G. C. Smith
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The inhibitory receptor, FcγRIIb, is reported to limit autoimmune B cell response. Here the authors show that FcγRIIb has a dual role in both human and mouse, with reduced FcγRIIb expression or function associated with enhanced pre-immune B cell t
Externí odkaz:
https://doaj.org/article/79eaab1ad06c4833bed4609c3c0f95a6
Publikováno v:
Immunology Letters. 254:6-12
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The bone marrow is a complex ecosystem in which hematopoietic and non-hematopoietic cells reside. In this review, we discuss the bone marrow niches in mice that facilitate the survival, maintenance, and differentiation of cells of hematopoietic origi
Externí odkaz:
https://doaj.org/article/497b4584edb04054b84eca4961e85ff2
Publikováno v:
médecine/sciences. 39:23-30
CXCR4 est un récepteur de chimiokine qui joue un rôle central dans la migration cellulaire mais également dans d’autres mécanismes essentiels, tels que le développement du système immunitaire. De concert avec son ligand naturel, la chimiokine
Autor:
Amélie Bonaud, Simon Clare, Valeria Bisio, John M. Sowerby, Shugang Yao, Hanne Ostergaard, Karl Balabanian, Kenneth G. C. Smith, Marion Espéli
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The generation of a potent humoral immune response by B cells relies on the integration of signals induced by the B cell receptor, toll-like receptors and both negative and positive co-receptors. Several reports also suggest that integrin signaling p
Externí odkaz:
https://doaj.org/article/f2a5a03a38854997b6ab77d7411f784f