Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mariolina Bruno"'
Autor:
Diletta Rosati, Isis Ricaño Ponce, Gloria S. Omosa-Manyonyi, Mariolina Bruno, Nelly W. Kamau, Martin Jaeger, Vinod Kumar, Mihai G. Netea, Andre J. A. M. van der Ven, Jaap ten Oever
Publikováno v:
Journal of Fungi, Vol 10, Iss 9, p 638 (2024)
Vulvovaginal candidiasis (VVC) affects up to 75% of women at least once during their lifetime, and up to 8% of women suffer from frequent recurrent episodes of VVC (RVVC). A lack of a protective host response underlies vaginal Candida infections, whi
Externí odkaz:
https://doaj.org/article/d45642d59e604681b192f2312cb2048a
Autor:
Rutger J. Röring, Wenchao Li, Ruiqi Liu, Mariolina Bruno, Bowen Zhang, Priya A. Debisarun, Orsolya Gaal, Medeea Badii, Viola Klück, Simone J.C.F.M. Moorlag, Frank van de Veerdonk, Yang Li, Leo A.B. Joosten, Mihai G. Netea
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109356- (2024)
Summary: Familial Mediterranean fever (FMF) is a periodic fever syndrome caused by variation in MEFV. FMF is known for IL-1β dysregulation, but the innate immune landscape of this disease has not been comprehensively described. Therefore, we studied
Externí odkaz:
https://doaj.org/article/1d73416b2879426590e716808a86b6e9
Autor:
Anaísa V. Ferreira, Sarantos Kostidis, Laszlo A. Groh, Valerie A.C.M. Koeken, Mariolina Bruno, Ilayda Baydemir, Gizem Kilic, Özlem Bulut, Theano Andriopoulou, Victoria Spanou, Kalliopi D. Synodinou, Theologia Gkavogianni, Simone J.C.F.M. Moorlag, L. Charlotte de Bree, Vera P. Mourits, Vasiliki Matzaraki, Werner J.H. Koopman, Frank L. van de Veerdonk, Georgios Renieris, Martin Giera, Evangelos J. Giamarellos-Bourboulis, Boris Novakovic, Jorge Domínguez-Andrés
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112658- (2023)
Summary: Itaconate is an immunomodulatory metabolite produced by immune cells under microbial stimulation and certain pro-inflammatory conditions and triggers antioxidant and anti-inflammatory responses. We show that dimethyl itaconate, a derivative
Externí odkaz:
https://doaj.org/article/6e7649ccdf4846afb0796f373689a5d6
Autor:
Mariolina Bruno, Intan M.W. Dewi, Vicky Matzaraki, Rob ter Horst, Marina Pekmezovic, Berenice Rösler, Laszlo Groh, Rutger J. Röring, Vinod Kumar, Yang Li, Agostinho Carvalho, Mihai G. Netea, Jean-Paul Latgé, Mark S. Gresnigt, Frank L. van de Veerdonk
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 647-663 (2021)
Candidiasis, aspergillosis, and mucormycosis cause the majority of nosocomial fungal infections in immunocompromised patients. Using an unbiased transcriptional profiling in PBMCs exposed to the fungal species causing these infections, we found a cor
Externí odkaz:
https://doaj.org/article/d6e9c6589cca465baf966bc074e18354
Autor:
Linda Davidson, Juul M.P.A. van den Reek, Mariolina Bruno, Florence van Hunsel, Ron M.C. Herings, Vasiliki Matzaraki, Collins K. Boahen, Vinod Kumar, Hans M.M. Groenewoud, Frank L. van de Veerdonk, Mihai G. Netea, Elke M.G.J. de Jong, Bart Jan Kullberg
Publikováno v:
The Lancet Regional Health. Europe, Vol 13, Iss , Pp 100266- (2022)
Summary: Background: Biologics directed against the T-helper (Th)-17 pathway have been approved for several inflammatory diseases. Interleukin (IL)-17 is involved in anti-Candida host defense, and clinical trials suggested increased candidiasis incid
Externí odkaz:
https://doaj.org/article/10c27b516f674a5996918493da5804b9
Autor:
Mariolina Bruno, Robter Horst, Marina Pekmezovic, Vinod Kumar, Yang Li, Mihai G. Netea, Jean-Paul Latgé, Mark S. Gresnigt, Frank L. van de Veerdonk
Publikováno v:
Data in Brief, Vol 35, Iss , Pp 106928- (2021)
Using a comparative RNA-Sequencing based transcriptional profiling approach, responses of primary human peripheral blood mononuclear cells (PBMCs) to common human pathogenic fungi have been characterized (Bruno et al. Computational and Structural Bio
Externí odkaz:
https://doaj.org/article/62332648f3594adf9011987af3c2153c
Autor:
Jorge Domínguez-Andrés, Rob J.W. Arts, Siroon Bekkering, Harsh Bahrar, Bastiaan A. Blok, L. Charlotte J. de Bree, Mariolina Bruno, Özlem Bulut, Priya A. Debisarun, Helga Dijkstra, Jéssica Cristina dos Santos, Anaísa V. Ferreira, Daniela Flores-Gomez, Laszlo A. Groh, Inge Grondman, Leonie Helder, Cor Jacobs, Liesbeth Jacobs, Trees Jansen, Gizem Kilic, Viola Klück, Valerie A.C.M. Koeken, Heidi Lemmers, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jelmer H. van Puffelen, Katrin Rabold, Rutger J. Röring, Diletta Rosati, Helin Tercan, Julia van Tuijl, Jessica Quintin, Reinout van Crevel, Niels P. Riksen, Leo A.B. Joosten, Mihai G. Netea
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100365- (2021)
Summary: A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous secondary stimuli. This concept has been termed “trained immunity.” We outline he
Externí odkaz:
https://doaj.org/article/e0ee4ea53a9e4be785098507068f1cd9
Autor:
Vera P Mourits, Jelmer H vanPuffelen, Boris Novakovic, Mariolina Bruno, Anaísa V Ferreira, Rob JW Arts, Laszlo Groh, Tania O Crișan, Jelle Zwaag, Elisa Jentho, Matthijs Kox, Peter Pickkers, Frank L van deVeerdonk, Sebastian Weis, Egbert Oosterwijk, Sita H Vermeulen, Mihai G Netea, Leo AB Joosten
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 2, Pp n/a-n/a (2021)
Abstract Objectives Histone methyltransferase G9a, also known as Euchromatic Histone Lysine Methyltransferase 2 (EHMT2), mediates H3K9 methylation which is associated with transcriptional repression. It possesses immunomodulatory effects and is overe
Externí odkaz:
https://doaj.org/article/6241b566bf084db2b5a557cb91065978
Autor:
Milou M.F. Schuurbiers, Mariolina Bruno, Sanne M.H. Zweijpfenning, Cecile Magis-Escurra, Martin Boeree, Mihai G. Netea, Jakko van Ingen, Frank van de Veerdonk, Wouter Hoefsloot
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
The prevalence of Mycobacterium abscessus infections in non-cystic fibrosis (CF) patients has increased in recent years. In this study, we investigate whether immune defects explain the apparent susceptibility to this opportunistic infection in non-C
Externí odkaz:
https://doaj.org/article/3ada5390b8e14c63bd4e809c429861fd
Autor:
Mariolina Bruno, Sanne M.H. Zweijpfenning, Jeske Verhoeven, Martin J. Boeree, Mihai G. Netea, Frank L. van de Veerdonk, Jakko van Ingen, Wouter Hoefsloot
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
Externí odkaz:
https://doaj.org/article/dfce60189551407ebac9d17bccf542dd