Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mariola Gordo"'
Autor:
Félix Calderón, María J. Chaparro, María Luisa León, Lourdes Rueda, Mariola Gordo, María Isabel Castellote, Esther Fernández, Jorge Fernández, Beatriz Hernández Díaz, Laura Fernández de las Heras
Combating Malaria is still clearly required. According to last WHO report > 200 million cases of malaria and > 400,000 deaths were reported during 2017. Since 2010, emerging resistance to current front-line ACTs (Artemisinin Combination Therapies) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87d08df17f9cfdd947dabe9ccc993f87
https://doi.org/10.1016/bs.armc.2019.07.001
https://doi.org/10.1016/bs.armc.2019.07.001
Autor:
Mariola Gordo, Elena Sandoval, Jose M. Coteron, Jiri Gut, Beatriz Hernández Díaz, María J. Chaparro, Jennifer Legac, Santiago Ferrer, David Catterick, Julia Castro, Juan Miguel, Maria L. Marco, Pilar Ventosa, Philip J. Rosenthal, Vicente Muñoz, Jose M. Fiandor, José Ruiz, Juan C. de la Rosa, Francisco J. Gamo, Esther Porras, Esther Fernández, Laura Fernández de las Heras
Publikováno v:
Journal of Medicinal Chemistry. 53:6129-6152
Falcipain-2 and falcipain-3 are papain-family cysteine proteases of the malaria parasite Plasmodium falciparum that are responsible for host hemoglobin hydrolysis to provide amino acids for parasite protein synthesis. Different heteroarylnitrile deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26636cd9e1d7aaed39cee9baeb817bce
https://doi.org/10.1021/jm100556b
https://doi.org/10.1021/jm100556b
Autor:
Mariola Gordo, María J. Chaparro, María Belén Jiménez-Díaz, Esther Fernández, María Santos Martínez, Albane Kessler, Isabel Castellote, Francisco-Javier Gamo, Lourdes Rueda, Adolfo García-Pérez, Juan C. de la Rosa, Laura M. Sanz, Julia Castro-Pichel, Simon J. F. Macdonald
Publikováno v:
ACS medicinal chemistry letters. 2(11)
Rapid triaging of three series of related hits selected from the Tres Cantos Anti-Malarial Set (TCAMS) are described. A triazolopyrimidine series was deprioritized due to delayed inhibition of parasite growth. A lactic acid series has derivatives wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357f36d32318de14c47a9c6d4bf33f16
https://pubmed.ncbi.nlm.nih.gov/24900273
https://pubmed.ncbi.nlm.nih.gov/24900273
Autor:
Beatriz Hernández Díaz, Esther Porras, Esther Fernández, José Ruiz, María J. Chaparro, Francisco J. Gamo, Julia Castro, Elena Sandoval, Juan C. de la Rosa, Jose M. Fiandor, Laura Fernández de las Heras, Jiri Gut, Jennifer Legac, David Catterick, Mariola Gordo, Jose M. Coteron, Santiago Ferrer, Philip J. Rosenthal, Maria L. Marco, Juan Miguel, Vicente Muñoz, Pilar Ventosa
Publikováno v:
Journal of Medicinal Chemistry. 53:7885-7886
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78e0b88e8f139ac93afc7e0328dd16cf
https://doi.org/10.1021/jm101228f
https://doi.org/10.1021/jm101228f
Autor:
Jose M. CoteroÌn, David Catterick, Julia Castro, MariÌa J. Chaparro, Beatriz DiÌaz, Esther FernaÌndez, Santiago Ferrer, Francisco J. Gamo, Mariola Gordo, Jiri Gut, Laura de las Heras, Jennifer Legac, Maria Marco, Juan Miguel, Vicente MunÌoz, Esther Porras, Juan C. de la Rosa, Jose R. Ruiz, Elena Sandoval, Pilar Ventosa
Publikováno v:
Journal of Medicinal Chemistry; Aug2010, Vol. 53 Issue 16, p6129-6152, 24p
Autor:
Kelly Chibale
Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written b