Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mario Wiletel"'
Autor:
Nicolas Granofszky, Andreas M. Farkas, Moritz Muckenhuber, Benedikt Mahr, Lukas Unger, Svenja Maschke, Nina Pilat, Raimund Holly, Mario Wiletel, Heinz Regele, Thomas Wekerle
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Transfer of recipient regulatory T cells (Tregs) induces mixed chimerism and tolerance in an irradiation-free bone marrow (BM) transplantation (BMT) model involving short-course co-stimulation blockade and mTOR inhibition. Boosting endogenous Tregs p
Externí odkaz:
https://doaj.org/article/fa158defd8df4311aa71d14ebd1bd017
Autor:
Thomas Wekerle, Lukas Unger, Mario Wiletel, Anna M. Weijler, Romy Steiner, Nicolas Granofszky, Heinz Regele, Moritz Muckenhuber, Lisa Dorner, Nina Pilat, Benedikt Mahr
Publikováno v:
American Journal of Transplantation
Eliminating cytoreductive conditioning from chimerism‐based tolerance protocols would facilitate clinical translation. Here we investigated the impact of major histocompatibility complex (MHC) and minor histocompatibility antigen (MiHA) barriers on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029b03e8f1168d21a80b3b11cb5d89f6
http://europepmc.org/articles/PMC7984377
http://europepmc.org/articles/PMC7984377
Autor:
Joanna Warren, Thomas Wekerle, Mario Wiletel, Nina Pilat, Romy Steiner, Theresa M. Corpuz, Jonathan Sprent, Kylie E. Webster, Anna M. Weijler, Benedikt Mahr
Publikováno v:
Proc Natl Acad Sci U S A
Injection of Interleukin-2 (IL-2) complexed with a particular anti–IL-2 monoclonal antibody (mab) JES6-1 has been shown to selectively expand CD4(+)Foxp3(+) T regulatory T cells (Tregs) in vivo. Although the potency of this approach with regard to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbfa9d129b4432a3ff2026f0bbd9d7c
https://doi.org/10.1073/pnas.1903165116
https://doi.org/10.1073/pnas.1903165116
Autor:
Svenja Maschke, Thomas Wekerle, Mario Wiletel, Nina Pilat, Nicolas Granofszky, Moritz Muckenhuber, Benedikt Mahr, Karin Hock
Publikováno v:
American Journal of Transplantation
Resistance to parental bone marrow (BM) grafts in F1 hybrid recipients is due to natural killer (NK) cell–mediated rejection triggered through “missing self” recognition. “Hybrid resistance” has usually been investigated in lethally irradia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f23fe64ce7a60dacb798cc6e0aaf0f
http://europepmc.org/articles/PMC6492153
http://europepmc.org/articles/PMC6492153
Autor:
Philipp Sabler, Heinz Regele, Karin Hock, Lukas Unger, Benedikt Mahr, Thomas Wekerle, Christoph Klaus, Mario Wiletel, Nina Pilat, Ivan Kristo, Christoph Schwarz
Publikováno v:
The Journal of Heart and Lung Transplantation. 37:1119-1130
Background The mixed chimerism approach for intentional induction of donor-specific tolerance was shown to be successful in various models from mice to humans. For transplant patients, the approach would obviate the need for long-term immunosuppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da29d9638c00e773974bdbcf61aa1fa3
https://doi.org/10.1016/j.healun.2018.03.016
https://doi.org/10.1016/j.healun.2018.03.016