Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Mario Vassalle"'
Autor:
Leonardo Bocchi, Monia Savi, Gallia Graiani, Stefano Rossi, Aldo Agnetti, Francesca Stillitano, Costanza Lagrasta, Silvana Baruffi, Roberta Berni, Caterina Frati, Mario Vassalle, Umberto Squarcia, Elisabetta Cerbai, Emilio Macchi, Donatella Stilli, Federico Quaini, Ezio Musso
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17750 (2011)
Heart repair by stem cell treatment may involve life-threatening arrhythmias. Cardiac progenitor cells (CPCs) appear best suited for reconstituting lost myocardium without posing arrhythmic risks, being commissioned towards cardiac phenotype. In this
Externí odkaz:
https://doaj.org/article/25718372cf8949d1aae3b1a499700e19
Autor:
Leonardo Bocchi, Mario Vassalle
Publikováno v:
Experimental Physiology. 93:347-361
The aim of our experiments was to investigate by means of a whole cell patch-clamp technique the characteristics of the slowly inactivating sodium current (I(Na2)) found in the plateau range in canine cardiac Purkinje single cells. The I(Na2) was sep
Publikováno v:
Biochemical and Biophysical Research Communications. 355:28-33
Background and Aim: The action potential plateau of Purkinje fibers is particularly sensitive to tetrodotoxin (TTX) and this could be due to a TXX-sensitive Na + current. The expression of TTX-sensitive neuronal Na v 1.1 and Na v 1.2 isoforms has bee
Publikováno v:
Experimental Physiology. 92:161-173
The action potential of Purkinje fibres is markedly shortened by tetrodotoxin, suggesting the possibility that a slowly inactivating sodium current might flow during the plateau. The aim of the present experiments was to investigate, in canine cardia
Autor:
Michael P. Nett, Mario Vassalle
Publikováno v:
Journal of Molecular and Cellular Cardiology. 35:1257-1276
The role of diastolic voltage oscillations in the initiation and maintenance of pacemaker discharge was studied in guinea pig-isolated sino-atrial (SA) node by means of a microelecrode technique. When [K + ] o is suitably increased, the maximum diast
Autor:
Hengtao Zhang, Mario Vassalle
Publikováno v:
Journal of Biomedical Science. 10:179-192
Among the mechanisms proposed for the increase in discharge of sino-atrial node (SAN) by norepinephrine (NE) are an increase in the hyperpolarization-activated current I(f) and in the slow inward current I(Ca,L). If I(f) is the primary mechanism, ces
Autor:
Hengtao Zhang, Mario Vassalle
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 79:963-976
The role of IK (delayed rectifier current) and If (hyperpolarization-activated current) in dominant and subsidiary pacemaker ranges was studied in single myocytes isolated from the guinea pig sino-atrial node by means of a perforated patch-clamp tech
Autor:
Mario Vassalle, Qi-Ying Liu
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 77:383-397
The role of Na-Ca exchange in the membrane potential changes caused by repetitive activity ("drive") was studied in guinea pig single ventricular myocytes exposed to different [Ca2+]o. The following results were obtained. (i) In 5.4 mM [Ca2+]o, the a
Autor:
Jian-Bing Shen, Mario Vassalle
Publikováno v:
Journal of Biomedical Science. 6:161-175
The mechanisms by which different concentrations of cesium modify membrane potentials and currents were investigated in guinea pig single ventricular myocytes. In a dose-dependent manner, cesium reversibly decreases the resting potential and action p
Autor:
Qi-Ying Liu, Mario Vassalle
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 77:383-397