Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Mario T Philipp"'
Autor:
Monica E Embers, Nicole R Hasenkampf, Mary B Jacobs, Amanda C Tardo, Lara A Doyle-Meyers, Mario T Philipp, Emir Hodzic
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189071 (2017)
The efficacy and accepted regimen of antibiotic treatment for Lyme disease has been a point of significant contention among physicians and patients. While experimental studies in animals have offered evidence of post-treatment persistence of Borrelia
Externí odkaz:
https://doaj.org/article/5dc59edc4c684b31a0770a258f675b9b
Autor:
Monica E Embers, Stephen W Barthold, Juan T Borda, Lisa Bowers, Lara Doyle, Emir Hodzic, Mary B Jacobs, Nicole R Hasenkampf, Dale S Martin, Sukanya Narasimhan, Kathrine M Phillippi-Falkenstein, Jeanette E Purcell, Marion S Ratterree, Mario T Philipp
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
[This corrects the article on p. e29914 in vol. 7.].
Externí odkaz:
https://doaj.org/article/54f34e994f1a4485a45604202e8ab205
Autor:
Aarti Gautam, Saurabh Dixit, Monica Embers, Rajeev Gautam, Mario T Philipp, Shree R Singh, Lisa Morici, Vida A Dennis
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43860 (2012)
C57BL/6J (C57) mice develop mild arthritis (Lyme disease-resistant) whereas C3H/HeN (C3H) mice develop severe arthritis (Lyme disease-susceptible) after infection with the spirochete Borrelia burgdorferi. We hypothesized that susceptibility and resis
Externí odkaz:
https://doaj.org/article/8be0cfaa76bd43fcaab47a173e7c6a8e
Autor:
Tao Lin, Lihui Gao, Chuhua Zhang, Evelyn Odeh, Mary B Jacobs, Loïc Coutte, George Chaconas, Mario T Philipp, Steven J Norris
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47532 (2012)
The identification of genes important in the pathogenesis of Lyme disease Borrelia has been hampered by exceedingly low transformation rates in low-passage, infectious organisms. Using the infectious, moderately transformable B. burgdorferi derivativ
Externí odkaz:
https://doaj.org/article/0d35d82b881143999c4de66866e75e39
Autor:
Monica E Embers, Stephen W Barthold, Juan T Borda, Lisa Bowers, Lara Doyle, Emir Hodzic, Mary B Jacobs, Nicole R Hasenkampf, Dale S Martin, Sukanya Narasimhan, Kathrine M Phillippi-Falkenstein, Jeanette E Purcell, Marion S Ratterree, Mario T Philipp
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29914 (2012)
The persistence of symptoms in Lyme disease patients following antibiotic therapy, and their causes, continue to be a matter of intense controversy. The studies presented here explore antibiotic efficacy using nonhuman primates. Rhesus macaques were
Externí odkaz:
https://doaj.org/article/73040572d77242bf8e8692a53e0ce1bc
Publikováno v:
PLoS Pathogens, Vol 5, Iss 12, p e1000679 (2009)
Antigenic variation plays a vital role in the pathogenesis of many infectious bacteria and protozoa including Borrelia burgdorferi, the causative agent of Lyme disease. VlsE, a 35 kDa surface-exposed lipoprotein, undergoes antigenic variation during
Externí odkaz:
https://doaj.org/article/0de1fee6ceb0401fae2cf688a2c50ce6
Publikováno v:
PLoS Pathogens, Vol 5, Iss 11, p e1000659 (2009)
Inflammation has long been implicated as a contributor to pathogenesis in many CNS illnesses, including Lyme neuroborreliosis. Borrelia burgdorferi is the spirochete that causes Lyme disease and it is known to potently induce the production of inflam
Externí odkaz:
https://doaj.org/article/44461747e2d74ac0b8eaec882d677e4e
Publikováno v:
Pathogens, Vol 12, Iss 1, p 132 (2023)
The blacklegged tick, Ixodes scapularis, is the predominant vector of Borrelia burgdorferi, the agent of Lyme disease in the USA. Natural hosts of I. scapularis such as Peromyscus leucopus are repeatedly infested by these ticks without acquiring tick
Externí odkaz:
https://doaj.org/article/fe9144a3b7884ad9b0f0463793697ee7
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Externí odkaz:
https://doaj.org/article/82398e22d62e4b7681ee750acfa44f52
Multi-platform Approach for Microbial Biomarker Identification Using Borrelia burgdorferi as a Model
Autor:
Kathryn J. Pflughoeft, Michael Mash, Nicole R. Hasenkampf, Mary B. Jacobs, Amanda C. Tardo, D. Mitchell Magee, Lusheng Song, Joshua LaBaer, Mario T. Philipp, Monica E. Embers, David P. AuCoin
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
The identification of microbial biomarkers is critical for the diagnosis of a disease early during infection. However, the identification of reliable biomarkers is often hampered by a low concentration of microbes or biomarkers within host fluids or