Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Mario T Philipp"'
Publikováno v:
Pathogens, Vol 12, Iss 1, p 132 (2023)
The blacklegged tick, Ixodes scapularis, is the predominant vector of Borrelia burgdorferi, the agent of Lyme disease in the USA. Natural hosts of I. scapularis such as Peromyscus leucopus are repeatedly infested by these ticks without acquiring tick
Externí odkaz:
https://doaj.org/article/fe9144a3b7884ad9b0f0463793697ee7
Autor:
Amanda R. Burmeister, M. Brittany Johnson, Vinita S. Chauhan, Megan J. Moerdyk-Schauwecker, Ada D. Young, Ian D. Cooley, Alejandra N. Martinez, Geeta Ramesh, Mario T. Philipp, Ian Marriott
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background The tachykinin substance P (SP) is recognized to exacerbate inflammation at peripheral sites via its target receptor, neurokinin 1 receptor (NK-1R), expressed by leukocytes. More recently, SP/NK-1R interactions have been associate
Externí odkaz:
https://doaj.org/article/96049e4fe6d543dd8914c0da8333e541
Autor:
Geetha Parthasarathy, Mario T. Philipp
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background In previous studies, human oligodendrocytes were demonstrated to undergo apoptosis in the presence of Borrelia burgdorferi under an inflammatory milieu. Subsequently, we determined that the MEK/ERK pathway played a significant rol
Externí odkaz:
https://doaj.org/article/63a69e0caada46238c0fea98073a2bef
Multi-platform Approach for Microbial Biomarker Identification Using Borrelia burgdorferi as a Model
Autor:
Kathryn J. Pflughoeft, Michael Mash, Nicole R. Hasenkampf, Mary B. Jacobs, Amanda C. Tardo, D. Mitchell Magee, Lusheng Song, Joshua LaBaer, Mario T. Philipp, Monica E. Embers, David P. AuCoin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
The identification of microbial biomarkers is critical for the diagnosis of a disease early during infection. However, the identification of reliable biomarkers is often hampered by a low concentration of microbes or biomarkers within host fluids or
Externí odkaz:
https://doaj.org/article/4a4842e7774b4d27897bba84fc03c345
Autor:
Monica E Embers, Nicole R Hasenkampf, Mary B Jacobs, Amanda C Tardo, Lara A Doyle-Meyers, Mario T Philipp, Emir Hodzic
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189071 (2017)
The efficacy and accepted regimen of antibiotic treatment for Lyme disease has been a point of significant contention among physicians and patients. While experimental studies in animals have offered evidence of post-treatment persistence of Borrelia
Externí odkaz:
https://doaj.org/article/5dc59edc4c684b31a0770a258f675b9b
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Cytokines and chemokines are proteins that coordinate the immune response throughout the body. The dysregulation of cytokines and chemokines is a central feature in the development of neuroinflammation, neurodegeneration, and demyelination both in th
Externí odkaz:
https://doaj.org/article/c53777fb8aab4c56b104c13abd8767aa
Autor:
Monica E Embers, Stephen W Barthold, Juan T Borda, Lisa Bowers, Lara Doyle, Emir Hodzic, Mary B Jacobs, Nicole R Hasenkampf, Dale S Martin, Sukanya Narasimhan, Kathrine M Phillippi-Falkenstein, Jeanette E Purcell, Marion S Ratterree, Mario T Philipp
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
[This corrects the article on p. e29914 in vol. 7.].
Externí odkaz:
https://doaj.org/article/54f34e994f1a4485a45604202e8ab205
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Externí odkaz:
https://doaj.org/article/82398e22d62e4b7681ee750acfa44f52
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
In this article we review the apoptotic mechanisms most frequently encountered in bacterial infections of the central nervous system (CNS). We focus specifically on apoptosis of neural cells (neurons and glia), and provide first an overview of the ph
Externí odkaz:
https://doaj.org/article/f0a9d01eb5434fbdb8910f13b3d2934e
Autor:
Monica E. Embers, Stephen W. Barthold, Juan T. Borda, Lisa Bowers, Lara Doyle, Emir Hodzic, Mary B. Jacobs, Nicole R. Hasenkampf, Dale S. Martin, Sukanya Narasimhan, Kathrine M. Phillippi-Falkenstein, Jeanette E. Purcell, Marion S. Ratterree, Mario T. Philipp
Publikováno v:
PLoS ONE, Vol 7, Iss 4 (2012)
Externí odkaz:
https://doaj.org/article/6fe2c3af0ca041d386656b487fde723b