Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Mario Santinami"'
Autor:
Adele Busico, Monica Rodolfo, Lorenza Di Guardo, Michele Del Vecchio, Licia Rivoltini, Laura Bergamaschi, Viviana Vallacchi, Mario Santinami, Elisabetta Vergani, Mara Cossa, Chiara Gargiuli, Andrea Devecchi, Matteo Dugo, Loris De Cecco, Stefano Cavalieri, Barbara Valeri, Elena Tamborini, Gianfrancesco Gallino, Marialuisa Sensi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Durable remissions are observed in 10%–20% of treated patients with advanced metastatic melanoma but the factors associated with long-term complete clinical responses are largely unknown. Here, we report the molecular characteristics of tumor evolu
Externí odkaz:
https://doaj.org/article/6ee6e9735e44433696b169cef2b40458
Autor:
Andrea Anichini, Alessandra Molla, Gabriella Nicolini, Valentina Eleonora Perotti, Francesco Sgambelluri, Alessia Covre, Carolina Fazio, Maria Fortunata Lofiego, Anna Maria Di Giacomo, Sandra Coral, Antonella Manca, Maria Cristina Sini, Marina Pisano, Teresa Noviello, Francesca Caruso, Silvia Brich, Giancarlo Pruneri, Andrea Maurichi, Mario Santinami, Michele Ceccarelli, Giuseppe Palmieri, Michele Maio, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium AIRC (EPICA) investigators
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Improvement of efficacy of immune checkpoint blockade (ICB) remains a major clinical goal. Association of ICB with immunomodulatory epigenetic drugs is an option. However, epigenetic inhibitors show a heterogeneous landscape of ac
Externí odkaz:
https://doaj.org/article/79c74f16caf34f389f373906c070b84d
Autor:
Saveria Tropea, Paolo Del Fiore, Andrea Maurichi, Roberto Patuzzo, Mario Santinami, Simone Ribero, Pietro Quaglino, Virginia Caliendo, Lorenzo Borgognoni, Serena Sestini, Giuseppe Giudice, Eleonora Nacchiero, Corrado Caracò, Adriana Cordova, Nicola Solari, Dario Piazzalunga, Francesca Tauceri, Paolo Carcoforo, Maurizio Lombardo, Sara Cavallari, Simone Mocellin, Italian Melanoma Intergroup (IMI)
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background The management of melanoma patients with metastatic melanoma in the sentinel nodes (SN) is evolving based on the results of trials questioning the impact of completion lymph node dissection (CLND) and demonstrating the efficacy of
Externí odkaz:
https://doaj.org/article/355e06452687480c9f4e48af571d22a7
Autor:
Bart Neyns, Lisa Zimmer, Caroline Robert, Celeste Lebbe, Olivier Michielin, Omid Hamid, Anne Zaremba, Oliver Klein, Ruth Plummer, Joanna Mangana, Paolo A Ascierto, Katharina C Kähler, Georgina V Long, Ryan Sullivan, Grant A McArthur, Michael Weichenthal, Egle Ramelyte, Meghan J Mooradian, Douglas B Johnson, Alexander Shoushtari, Christian U Blank, Judith M Versluis, Prachi Bhave, Claudia Trojanello, Lu Si, Inderjit Mehmi, Tasnia Ahmed, Alexander M Menzies, Adnan Khattak, Severine Roy, Matteo S Carlino, Paul C Lorigan, Clara Allayous, Rachel Roberts-Thomson, Florentia Dimitriou, Kathleen Batty, Thierry Lesimple, Serigne N Lo, Alexandre Wicky, Richard Heywood, Lena Tran, Anna Stansfeld, Julia K Schwarze, Andrea Maurichi, Hui-Ling Yeoh, Mario Santinami, Andrew M Haydon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Acral melanoma is a rare melanoma subtype with poor prognosis. Importantly, these patients were not identified as a specific subgroup in the landmark melanoma trials involving ipilimumab and the anti-programmed cell death protein-1 (PD-1)
Externí odkaz:
https://doaj.org/article/0b1c2b670e1e4ec1b95b97b6b085c47b
Autor:
Elisabetta Vergani, Matteo Dugo, Mara Cossa, Simona Frigerio, Lorenza Di Guardo, Gianfrancesco Gallino, Ilaria Mattavelli, Barbara Vergani, Luca Lalli, Elena Tamborini, Barbara Valeri, Chiara Gargiuli, Eriomina Shahaj, Marina Ferrarini, Elisabetta Ferrero, Macarena Gomez Lira, Veronica Huber, Michele Del Vecchio, Marialuisa Sensi, Biagio Eugenio Leone, Mario Santinami, Licia Rivoltini, Monica Rodolfo, Viviana Vallacchi
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Targeted therapy with BRAF and MEK inhibitors has improved the survival of patients with BRAF-mutated metastatic melanoma, but most patients relapse upon the onset of drug resistance induced by mechanisms including genetic and epi
Externí odkaz:
https://doaj.org/article/a1bcbc7c9c6f40e4a638028a386aaac5
Autor:
Viviana Vallacchi, Chiara Camisaschi, Matteo Dugo, Elisabetta Vergani, Paola Deho, Ambra Gualeni, Veronica Huber, Annunziata Gloghini, Andrea Maurichi, Mario Santinami, Marialuisa Sensi, Chiara Castelli, Licia Rivoltini, Monica Rodolfo
Publikováno v:
Genes, Vol 7, Iss 12, p 124 (2016)
Sentinel node biopsy (SNB) is a main staging biomarker in melanoma and is the first lymph node to drain the tumor, thus representing the immunological site where anti-tumor immune dysfunction is established and where potential prognostic immune marke
Externí odkaz:
https://doaj.org/article/0e8ad86f64cc44b88ffb59277d260c17
Autor:
Mariantonia Logozzi, Angelo De Milito, Luana Lugini, Martina Borghi, Luana Calabrò, Massimo Spada, Maurizio Perdicchio, Maria Lucia Marino, Cristina Federici, Elisabetta Iessi, Daria Brambilla, Giulietta Venturi, Francesco Lozupone, Mario Santinami, Veronica Huber, Michele Maio, Licia Rivoltini, Stefano Fais
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5219 (2009)
BACKGROUND: Metastatic melanoma is an untreatable cancer lacking reliable and non-invasive markers of disease progression. Exosomes are small vesicles secreted by normal as well as tumor cells. Human tumor-derived exosomes are involved in malignant p
Externí odkaz:
https://doaj.org/article/777e9b167fd447db947c5d1cba838ee7
Autor:
Ilaria Mattavelli, Roberto Patuzzo, Carlotta Galeone, Claudio Pelucchi, Gianfranco Gallino, Andrea Leva, Barbara Valeri, Mario Santinami, Andrea Maurichi
Publikováno v:
Melanoma Research.
Autor:
Andrea Maurichi, Francesco Barretta, Roberto Patuzzo, Laura Sala, Rosalba Miceli, Gianfranco Gallino, Ilaria Mattavelli, Andrea Leva, Nicolò Simonotti, Bianca Taglione, Mara Cossa, Alessia Belotti, Barbara Valeri, Umberto Cortinovis, Mario Santinami
Publikováno v:
JAMA Dermatology.
ImportanceMelanoma guidelines recommend surgical excision with 10-mm margins for T1 melanoma. However, this procedure may be problematic at sites close to critical structures such as the scalp, face, external genitalia, acral, periumbilical, and peri
Autor:
Andrea Anichini, Mario Santinami, Roberto Patuzzo, Andrea Maurichi, Fernando Ravagnani, Flavio Arienti, Alessandra Molla, Claudia Vegetti, Roberta Mortarini
Supplementary Data from Impaired STAT Phosphorylation in T Cells from Melanoma Patients in Response to IL-2: Association with Clinical Stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fabce715707712a059d6e3e6babfa2
https://doi.org/10.1158/1078-0432.22439968.v1
https://doi.org/10.1158/1078-0432.22439968.v1