Výsledky vyhledávání - "Mario Salwiczek"

Akademický článek

Hyperosmotic Infusion and Oxidized Surfaces Are Essential for Biofilm Formation of Staphylococcus capitis From the Neonatal Intensive Care Unit

Autor: Yue Qu, Yali Li, David R. Cameron, Christopher D. Easton, Xuebo Zhu, Minli Zhu, Mario Salwiczek, Benjamin W. Muir, Helmut Thissen, Andrew Daley, John S. Forsythe, Anton Y. Peleg, Trevor Lithgow

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

Staphylococcus capitis is an opportunistic pathogen often implicated in bloodstream infections in the neonatal intensive care unit (NICU). This is assisted by its ability to form biofilms on indwelling central venous catheters (CVC), which are highly

Externí odkaz: https://doaj.org/article/ba6074acb9794946a3abebb71f0dd44a

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Enzymatic Building‐Block Synthesis for Solid‐Phase Automated Glycan Assembly

Autor: Fabio Parmeggiani, Sabine L. Flitsch, Kun Huang, João Louçano, Ashley P. Mattey, Andrea Marchesi, Tanistha Gupta, Mario Salwiczek

Publikováno v: Angewandte Chemie. 132:22642-22645

Automated chemical oligosaccharide synthesis is an attractive concept that has been successfully applied to a large number of target structures, but requires excess quantities of suitably protected and activated building blocks. Here we demonstrate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb113a73634862150d97cfb111ad8309
https://doi.org/10.1002/ange.202008067

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Automated glycan assembly of Streptococcus pneumoniae type 14 capsular polysaccharide fragments

Autor: Linda Del Bino, João Louçano, Peter Both, Andrea Marchesi, Mario Salwiczek, Roberto Adamo, Sabine L. Flitsch

Publikováno v: RSC Advances. 10:23668-23674

S. pneumoniae is a major human pathogen with increasing antibiotic resistance. Pneumococcal vaccines consist of capsular polysaccharide (CPS) or their related fragments conjugated to a carrier protein. The repeating unit of S. pneumoniae type 14 CPS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77d536801c9c41cffabb0ded72799668
https://doi.org/10.1039/d0ra01803a

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Enzymatic Building-Block Synthesis for Solid-Phase Automated Glycan Assembly

Autor: Sabine L. Flitsch, Ashley P. Mattey, Fabio Parmeggiani, João Louçano, Kun Huang, Andrea Marchesi, Mario Salwiczek, Tanistha Gupta

Publikováno v: Angewandte Chemie (International Ed. in English)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960f6b53fc3113704389a85ed1068339
http://hdl.handle.net/11311/1167178

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Hyperosmotic Infusion and Oxidized Surfaces Are Essential for Biofilm Formation of

Autor: Yue, Qu, Yali, Li, David R, Cameron, Christopher D, Easton, Xuebo, Zhu, Minli, Zhu, Mario, Salwiczek, Benjamin W, Muir, Helmut, Thissen, Andrew, Daley, John S, Forsythe, Anton Y, Peleg, Trevor, Lithgow

Publikováno v: Frontiers in Microbiology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1b52830a4fc657a117f799ab3265380
https://pubmed.ncbi.nlm.nih.gov/32477314

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Exploring the conformational preferences of 20-residue peptides in isolation: Ac-Ala19-Lys + H+vs. Ac-Lys-Ala19 + H+ and the current reach of DFT

Autor: Matthias Scheffler, Gerard Meijer, Mario Salwiczek, Peter Kupser, Mariana Rossi, Stephan Warnke, Gert von Helden, Franziska Schubert, Beate Koksch, Carsten Baldauf, Frank Filsinger, Volker Blum, Kevin Pagel

Publikováno v: PCCP Physical Chemistry Chemical Physics, 17, 7373-7385
PCCP Physical Chemistry Chemical Physics, 17, 11, pp. 7373-7385
Physical Chemistry Chemical Physics

A reliable, quantitative prediction of the structure of peptides based on their amino-acid sequence information is an ongoing challenge. We here explore the energy landscape of two unsolvated 20-residue peptides that result from a shift of the positi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b69e3b509e495cccb44f4dee8969fc
https://doi.org/10.1039/c4cp05541a

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Native like helices in a specially designed β peptide in the gas phase

Autor: Mario Salwiczek, Volker Blum, Carsten Baldauf, Stephan Warnke, Mariana Rossi, Matthias Scheffler, Franziska Schubert, Beate Koksch, Kevin Pagel, Gert von Helden

Publikováno v: Physical Chemistry Chemical Physics

In the natural peptides, helices are stabilized by hydrogen bonds that point backward along the sequence direction. Until now, there is only little evidence for the existence of analogous structures in oligomers of conformationally unrestricted β am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acea50150d795d2621f5661f8193c0f3
https://doi.org/10.1039/c4cp05216a

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Core-multishell nanotransporters enhance skin penetration of the cell-penetrating peptide low molecular weight protamine

Autor: Beate Koksch, Monika Schäfer-Korting, Nhung Do, Rainer Haag, Emanuel Fleige, Mario Salwiczek, Günther Weindl

Publikováno v: Polymers for Advanced Technologies. 25:1337-1341

Several peptides may enable innovative, sophisticated therapeutic approaches. Their hydrophilic nature and high molecular weight, however, often limit the applicability to topical and transdermal treatment. Aiming to enhance drug delivery to the skin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c802ce8c914accff0516c3352c8bbd92
https://doi.org/10.1002/pat.3362

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Cationic membrane-active peptides - anticancer and antifungal activity as well as penetration into human skin

Autor: Lisa Grohmann, Monika Schäfer-Korting, Mario Salwiczek, Beate Koksch, Günther Weindl, Nhung Do, Hans Christian Korting

Publikováno v: Experimental Dermatology. 23:326-331

Cationic antimicrobial peptides are ancient natural broad-spectrum antibiotics, and several compounds also exhibit anticancer activity. However, most applications pertain to bacterial infections, and treatment for skin cancer is less frequently consi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f307cf79492c608654dbd117982858
https://doi.org/10.1111/exd.12384

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Emerging rules for effective antimicrobial coatings

Autor: Keith M. McLean, Richard A. Strugnell, Helmut Thissen, Mario Salwiczek, Yue Qu, Trevor Lithgow, James Gardiner

Publikováno v: Trends in Biotechnology. 32:82-90

In order to colonize abiotic surfaces, bacteria and fungi undergo a profound change in their biology to form biofilms: communities of microbes embedded into a matrix of secreted macromolecules. Despite strict hygiene standards, biofilm-related infect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6181f84a6f14557f0a37b7ef531b9053
https://doi.org/10.1016/j.tibtech.2013.09.008

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