Zobrazeno 1 - 10
of 548
pro vyhledávání: '"Mario Salmona"'
Autor:
Alice Passoni, Monica Favagrossa, Marta Valenza, Giulia Birolini, Alessia Lanno, Caterina Mariotti, Elena Cattaneo, Mario Salmona, Laura Colombo, Renzo Bagnati
Publikováno v:
Talanta Open, Vol 9, Iss , Pp 100278- (2024)
Brain is most cholesterol-rich organ in the body. Since cholesterol does not cross the blood brain barrier, its metabolism is provided in situ by astrocytes and neurons, and it is crucial for maintaining sterol levels and neuronal integrity and funct
Externí odkaz:
https://doaj.org/article/e05b9e87a3194d3681b7b84925dc67b8
Autor:
Marzia Indrigo, Ilaria Morella, Daniel Orellana, Raffaele d'Isa, Alessandro Papale, Riccardo Parra, Antonia Gurgone, Daniela Lecca, Anna Cavaccini, Cezar M Tigaret, Alfredo Cagnotto, Kimberley Jones, Simon Brooks, Gian Michele Ratto, Nicholas D Allen, Mariah J Lelos, Silvia Middei, Maurizio Giustetto, Anna R Carta, Raffaella Tonini, Mario Salmona, Jeremy Hall, Kerrie Thomas, Riccardo Brambilla, Stefania Fasano
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp n/a-n/a (2023)
Abstract Cell signaling is central to neuronal activity and its dysregulation may lead to neurodegeneration and cognitive decline. Here, we show that selective genetic potentiation of neuronal ERK signaling prevents cell death in vitro and in vivo in
Externí odkaz:
https://doaj.org/article/07ec956f4df240a18ad3746f40460254
Autor:
Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giada Lavigna, Hasier Eraña, Gabriele Giachin, Laura Tapella, Liliana Comerio, Elena Restelli, Ilaria Raimondi, Saioa R. Elezgarai, Federica De Leo, Giacomo Quilici, Lorenzo Taiarol, Marvin Oldrati, Nuria L. Lorenzo, Sandra García-Martínez, Alfredo Cagnotto, Jacopo Lucchetti, Marco Gobbi, Ilaria Vanni, Romolo Nonno, Michele A. Di Bari, Mark D. Tully, Valentina Cecatiello, Giuseppe Ciossani, Sebastiano Pasqualato, Eelco Van Anken, Mario Salmona, Joaquín Castilla, Jesús R. Requena, Stefano Banfi, Giovanna Musco, Roberto Chiesa
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108223- (2023)
Externí odkaz:
https://doaj.org/article/b54cc5dafd374331865a0f0374b0327f
Autor:
Giulia Birolini, Marta Valenza, Ilaria Ottonelli, Francesca Talpo, Lucia Minoli, Andrea Cappelleri, Mauro Bombaci, Claudio Caccia, Caterina Canevari, Arianna Trucco, Valerio Leoni, Alice Passoni, Monica Favagrossa, Maria Rosaria Nucera, Laura Colombo, Saverio Paltrinieri, Renzo Bagnati, Jason Thomas Duskey, Riccardo Caraffi, Maria Angela Vandelli, Franco Taroni, Mario Salmona, Eugenio Scanziani, Gerardo Biella, Barbara Ruozi, Giovanni Tosi, Elena Cattaneo
Publikováno v:
Pharmacological Research, Vol 194, Iss , Pp 106823- (2023)
Evidence that Huntington's disease (HD) is characterized by impaired cholesterol biosynthesis in the brain has led to strategies to increase its level in the brain of the rapidly progressing R6/2 mouse model, with a positive therapeutic outcome. Here
Externí odkaz:
https://doaj.org/article/96c6f98820c54018a225e99542b0010a
Autor:
Marten Beeg, Sara Baroni, Arianna Piotti, Alessia Porta, Ada De Luigi, Alfredo Cagnotto, Marco Gobbi, Luisa Diomede, Mario Salmona
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12146 (2023)
We developed and validated a technology platform for designing and testing peptides inhibiting the infectivity of SARS-CoV-2 spike protein-based pseudoviruses. This platform integrates target evaluation, in silico inhibitor design, peptide synthesis,
Externí odkaz:
https://doaj.org/article/8b485bf67f304286932a246c4682d0fc
Autor:
Carlotta Ciaramelli, Alessandro Palmioli, Irene Angotti, Laura Colombo, Ada De Luigi, Gessica Sala, Mario Salmona, Cristina Airoldi
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The anti-Alzheimer disease (AD) activity reported for an aqueous cinnamon bark extract prompted us to investigate and compare the anti-amyloidogenic properties of cinnamon extracts obtained from both bark and bud, the latter being a very little explo
Externí odkaz:
https://doaj.org/article/d4a834e8c6434a37a8e73c119df244f2
Publikováno v:
Nutrients, Vol 15, Iss 8, p 1869 (2023)
The human gut microbiota, a complex community of microorganisms living in the digestive tract, consists of more than 1500 species distributed in more than 50 different phyla, with 99% of bacteria coming from about 30–40 species. The colon alone, wh
Externí odkaz:
https://doaj.org/article/44f27ec441a84dd4a4862e6b168d4545
Autor:
Martina B. Violatto, Giovanni Sitia, Laura Talamini, Annalisa Morelli, Ngoc Lan Tran, Qian Zhang, Atif Masood, Beatriz Pelaz, Indranath Chakraborty, Daxiang Cui, Wolfgang J. Parak, Mario Salmona, Neus G. Bastús, Victor Puntes, Paolo Bigini
Publikováno v:
Nanomaterials, Vol 13, Iss 7, p 1174 (2023)
Titanium dioxide nanoparticles (TiO2 NPs) are one of the main sources of the nanoparticulate matter exposure to humans. Although several studies have demonstrated their potential toxic effects, the real nature of the correlation between NP properties
Externí odkaz:
https://doaj.org/article/0761b21810e846a9b5c2fc48e3ef5f75
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Background Mutations of different genes often result in clinically similar diseases. Among the datasets of similar diseases, we analyzed the ‘phenotypic series’ from Online Mendelian Inheritance in Man and examined the similarity of the
Externí odkaz:
https://doaj.org/article/139ad3dd3af6490eba32c09e84a48913
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background Despite being caused by mutations in different genes, diseases in the same phenotypic series are clinically similar, as reported in Part I of this study. Here, in Part II, we hypothesized that the phenotypic series too might be cl
Externí odkaz:
https://doaj.org/article/337779895cc841b38ad255959a56951e