Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Mario Pinza"'
Autor:
Walter Luini, Alberto Mantovani, Angelo Guglielmotti, Pietro Transidico, Silvano Sozzani, Giada Frascaroli, Elena Riboldi, Sergio Bernasconi, Claudio Milanese, Mario Pinza, Francesca Mancini
Publikováno v:
British Journal of Pharmacology. 140:377-383
1. The present study was aimed to investigate the effect of benzydamine, an anti-inflammatory drug devoid of activity on arachidonic acid metabolism, on monocyte chemotaxis and to define the possible biochemical correlates of activity. 2. Benzydamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc2ed165294b0ea3b3855798910ecdf9
https://doi.org/10.1038/sj.bjp.0705428
https://doi.org/10.1038/sj.bjp.0705428
Autor:
Mario Pinza, Claudio Milanese, Carla Landolfi, Paolo Domiano, Bruno Macchia, Francesca Mancini, Aldo Balsamo, Isabella Coletta, Simona Rapposelli, Elisabetta Orlandini, Angelo Guglielmotti
Publikováno v:
European Journal of Medicinal Chemistry. 37:391-398
The (E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden](methyloxy)amine (5) and (arylmethyloxy)amines (6–12) were designed in order to verify the effects on the biological properties of the substitution of an aryl of selective diarylcycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f294a9b8e4bdf54dd35199999314bb06
https://doi.org/10.1016/s0223-5234(02)01359-4
https://doi.org/10.1016/s0223-5234(02)01359-4
Publikováno v:
Scopus-Elsevier
In rabbit nasal mucosa, free polypeptides and polypeptide-coated nanospheres are actively absorbed by the M cells present in specialized areas of the epithelium. Because polypeptide-coated nanosphere transport was abolished in the presence of free po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3200a488153a3c93fc6f57f6998c3fa
https://doi.org/10.1152/jappl.2001.91.1.211
https://doi.org/10.1152/jappl.2001.91.1.211
Autor:
Luisa Diomede, Alessandra Bruno, Paolo Fruscella, Mario Salmona, Lucia Massimiliano, Marcello Sottocorno, Mario Pinza, Marina Sironi, Nadia Polentarutti, Diego Albani, Angelo Guglielmotti, Annunciata Vecchi, Maria Romano, Alberto Mantovani
Publikováno v:
Laboratory Investigation. 80:1095-1100
The beneficial effects of statins on the reduction of cardiovascular events has been partly attributed to their anti-inflammatory properties. In the complex of the different pathogenetic events leading to atherosclerosis, recent data suggest a centra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0bff477082b527df8ca8ab83f65962
https://doi.org/10.1038/labinvest.3780115
https://doi.org/10.1038/labinvest.3780115
Publikováno v:
European Journal of Pharmacology. 400:35-41
The effects of trazodone and putative sigma (sigma) receptor ligands were investigated on KCl-stimulated release of glutamate (Glu) and gamma-aminobutyric acid (GABA) from cerebellar mossy fibre synaptosomes. Both trazodone and serotonin (5-HT) inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a603ab3fe6dbab4b2d2e51669e01c1
https://doi.org/10.1016/s0014-2999(00)00378-2
https://doi.org/10.1016/s0014-2999(00)00378-2
Autor:
Francesca Mancini, Marilena Giannangeli, Mario Pinza, Claudio Milanese, Massimo Mabilia, Carola Marani Toro
Publikováno v:
Biochemical Pharmacology. 58:851-859
Suramin, a symmetrical polysulfonated urea derivative, promotes the dissociation of trimeric human tumor necrosis factor-alpha (TNF-alpha) into biologically inactive subunits and prevents the interaction of TNF-alpha with its cellular receptors. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::875ed35fc905d534d4e6e110ef488791
https://doi.org/10.1016/s0006-2952(99)00150-1
https://doi.org/10.1016/s0006-2952(99)00150-1
Autor:
Daniela Corna, Tullio Bertani, Marina Morigi, Roberta Donadelli, Giuseppe Remuzzi, Carla Zoja, Mario Pinza, Angelo Guglielmotti, Giuditta Benedetti
Publikováno v:
Kidney International. 53:726-734
Bindarit retards renal disease and prolongs survival in murine lupus autoimmune disease. As an alternative to classical immunosuppressants in experimental lupus nephritis, we looked at bindarit, 2-methyl-2-{[1-phenylmethyl)-1H-indazol-3-y1]methoxy}pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420be94ad658bed0dd27bc0effe00042
https://doi.org/10.1046/j.1523-1755.1998.00804.x
https://doi.org/10.1046/j.1523-1755.1998.00804.x
Autor:
Paola Sacerdote, Simona Rapposelli, Aldo Balsamo, Sara Moretti, Mario Pinza, Maria Digiacomo, Silvia Franchi
Publikováno v:
Molecular pharmaceutics. 7(5)
Several nimesulide preparations (i.e., tablet form, gels) have been marketed, but no parenteral solution has achieved the market because of their low wettability and unsatisfactory chemical-physical properties required for parenteral use. In this pap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9f52163a844bceb7b38c74281b9f52
https://pubmed.ncbi.nlm.nih.gov/23282004
https://pubmed.ncbi.nlm.nih.gov/23282004
Autor:
Marina Sironi, Pietro Ghezzi, Claudio Milanese, Isabella Coletta, Angelo Guglielmotti, P. Pozzi, Nadia Polentarutti, A. Mantovani, Fabio Benigni, Mario Pinza, Annunciata Vecchi
Publikováno v:
Cytokine. 8:710-716
The present study was designed to assess the effect of N,N-dimethyl-3-[(1-benzyl-1H-indazol-3-yl)ossi]-1-propana mine (benzydamine) on in vivo and in vitro production of inflammatory cytokines. Benzydamine inhibited tumour necrosis factor-alpha (TNF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600c93354b972f276c1bacd76ddbae4e
https://doi.org/10.1006/cyto.1996.0094
https://doi.org/10.1006/cyto.1996.0094
Autor:
Silvano Banfi, Luciano Dorigotti, Ottorino Pozzi, Maurizio Magnani, Mario Pinza, M. T. Riccaboni, R. Biagetti, Carlo Farina, U. Pfeiffer, Alberto Cerri
Publikováno v:
Journal of Medicinal Chemistry. 36:4214-4220
A series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones were synthesized. These bicylic derivatives contain both the 2-pyrrolidinone and 4-imidazolidinone nuclei, already recognized as important for cognition enhancing activity. In addition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc54c4d4a3dd97431df66aee064ca22f
https://doi.org/10.1021/jm00078a011
https://doi.org/10.1021/jm00078a011