Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mario Meng-Chiang Kuo"'
Publikováno v:
PLoS Biology, Vol 6, Iss 10, p e223 (2008)
The RCK-containing MthK channel undergoes two inactivation processes: activation-coupled desensitization and acid-induced inactivation. The acid inactivation is mediated by the C-terminal RCK domain assembly. Here, we report that the desensitization
Externí odkaz:
https://doaj.org/article/0622d1d6754540b5a3c0ff67d96aa46e
Autor:
Richard E. Showalter, Jim Thomson, Yudou He, Mario Meng-Chiang Kuo, Richard Hickey, Wei-Jong Shia, Li-Chang Chen, Elena Brin, Eleanor Dagostino, Katherine Wu, Robert Almassy, Mariusz Stempniak
Publikováno v:
Oncotarget
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) binds to death receptors and induces apoptosis in various cancer cell lines while sparing normal cells. Recombinant TRAIL has shown good safety and efficacy profiles in preclinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920a1fcfc2cf7ef29450ed87d9dde742
http://europepmc.org/articles/PMC6319333
http://europepmc.org/articles/PMC6319333
Autor:
Subin Kim, So-Mi Yoon, Su-Geun Yang, Byung-Hak Yoon, Mario Meng-Chiang Kuo, Min Kyoung Kim, Jae Woo Jung, Senyon Choe, Yun-Hui Jeon
Publikováno v:
Oncotarget
// Jae Woo Jung 1, 4 , So-Mi Yoon 1 , Subin Kim 1 , Yun-Hui Jeon 1 , Byung-Hak Yoon 1 , Su-Geun Yang 3 , Min Kyoung Kim 3 , Senyon Choe 1, 2 , Mario Meng-Chiang Kuo 1, 2, 5 1 Protein Engineering Laboratory, Joint Center for Biosciences, Songdo Smart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eaccb9aa7ba04a829eb0103d338203c
https://doi.org/10.18632/oncotarget.12062
https://doi.org/10.18632/oncotarget.12062
Autor:
Mario Meng-Chiang Kuo1,2 mariokuo.jcb@gmail.com, Phuong Hong Nguyen1 phuong.hn.jcb@gmail.com, Yun-Hui Jeon1 eunice.jeon.jcb@gmail.com, Subin Kim1 subin.kim.jcb@gmail.com, So-Mi Yoon1 somi.jcb@gmail.com, Senyon Choe1,2 senyon.choe2@gmail.com
Publikováno v:
Microbial Cell Factories. 2014, Vol. 13 Issue 1, p1-22. 22p.
Publikováno v:
Biomaterials. 35:3172-3179
BMP-9, whose expression is highest in liver cells, has been demonstrated to regulate expression of enzymes involved in glucose homeostasis. However, the underlying mechanism of this effect has yet to be elucidated. We observed that MB109, a recombina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b560c692126eba7fb750f49c3a00a6c3
https://doi.org/10.1016/j.biomaterials.2013.12.063
https://doi.org/10.1016/j.biomaterials.2013.12.063
Publikováno v:
Aquaculture. :250-255
ATP-binding cassette (ABC) transporters are integral membrane proteins which carry diverse substrates across biological membranes. In this study, we report the cloning of a full-length, 2122-bp cDNA sequence encoding a gene of the ABC transporter sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba71dc0791507bc98088adefe8d75a6
https://doi.org/10.1016/j.aquaculture.2012.05.009
https://doi.org/10.1016/j.aquaculture.2012.05.009
Publikováno v:
Applied Microbiology and Biotechnology. 91:553-563
Microbial phytases are widely used as feed additive to increase phytate phosphorus utilization and to reduce fecal phytates and inorganic phosphate (iP) outputs. To facilitate the process of application, we engineered an Escherichia coli appA phytase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cd757b92d1f1dd1b25a8354b52d2ab
https://doi.org/10.1007/s00253-011-3279-2
https://doi.org/10.1007/s00253-011-3279-2
Autor:
Richard E. Showalter, Wei-Jong Shia, Jim Thomson, Elena Brin, Bob Almassy, Eleanor Dagostino, Li-Chang Chen, Richard Hickey, Mario Meng-Chiang Kuo, Katherine Wu, Yudou He
Publikováno v:
Cancer Research. 78:3902-3902
TNF-related apoptosis-inducing ligand (TRAIL) receptor agonists have shown good safety profile and efficacy in preclinical cancer models. However, clinical success has been limited due to poor PK and/or development of resistance to death receptor-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba05403b029c18e218eec9451a77fafd
https://doi.org/10.1158/1538-7445.am2018-3902
https://doi.org/10.1158/1538-7445.am2018-3902
Publikováno v:
Journal of Biological Chemistry. 282:24294-24301
Prokaryotic ion channels have been valuable in providing structural models for understanding ion filtration and channel-gating mechanisms. However, their functional examinations have remained rare and usually been carried out by incorporating purifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40d84167eb371ebdeca73cca2ec521a
https://doi.org/10.1074/jbc.m703618200
https://doi.org/10.1074/jbc.m703618200
Publikováno v:
Proceedings of the National Academy of Sciences. 104:2151-2156
The crystal structure of the RCK-containing MthK provides a molecular framework for understanding the ligand gating mechanisms of K + channels. Here we examined the macroscopic currents of MthK in enlarged Escherichia coli membrane by patch clamp and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31228048b58ac17810206f79ef6324d8
https://doi.org/10.1073/pnas.0609085104
https://doi.org/10.1073/pnas.0609085104