Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mario M. Mangino"'
Publikováno v:
Pancreas. 7:271-279
Pancreatic duct cells of the Syrian hamster were grown as monolayers on thin layers of type I collagen coated onto microporous membranes. The effects of a number of potential trophic factors were tested by their ability to increase [3H]thymidine inco
Publikováno v:
Carcinogenesis. 15(9)
Neoplastic transformation of Syrian golden hamster (SGH) pancreatic duct cells was induced by in vitro treatment with the direct-acting carcinogens N-methylnitrosourea (MNU) and N-(2-hydroxypropyl)nitrosourea (HPNU), with subsequent selection by sust
Publikováno v:
In vitro cellulardevelopmental biology : journal of the Tissue Culture Association. 26(9)
Epithelial cells isolated from fragments of hamster pancreas interlobular ducts were freed of fibroblast contamination by plating them on air-dried collagen, maintaining them in serum-free Dulbecco's modified Eagle's (DME):F12 medium suppleneted with
Publikováno v:
Carcinogenesis. 11(4)
The metabolism of the pancreatic carcinogen N-nitroso-bis(2-oxopropyl)amine (BOP) was studied using primary hepatocytes and acinar and duct cells isolated from Syrian hamsters. Metabolic activation of BOP was verified by detecting its conversion to C
Autor:
Richard A. Scanlan, Mario M. Mangino
Publikováno v:
Journal of Agricultural and Food Chemistry. 33:699-705
Publikováno v:
Carcinogenesis. 9:1763-1772
The rates of uptake of the carcinogen N-nitrosobis(2-oxopropyl)amine (BOP) by hepatocytes isolated from Fischer rats and Syrian hamsters were determined in order to investigate species differences in cellular transport of the carcinogen. Initial rate
Autor:
M. I. Usman, Mario M. Mangino, Keith Alvares, Shobha Thangada, Janardan K. Reddy, M. Sambasiva Rao
Publikováno v:
FEBS Letters. (2):205-210
Using the normal adult rat hepatocytes, plated on rat tail collagen-coated dishes and fed a chemically defined medium, we demonstrate here that ciprofibrate at 0.1 mM concentration, increases significantly the mRNA levels of fatty acyl-CoA oxidase, e
Autor:
Mario M. Mangino, Richard A. Scanlan
Publikováno v:
Journal of the American Society of Brewing Chemists. 40:55-57
The principal objective of this work was to investigate the formation and establish the identity of amine precursors for N-nitrosodimethylamine (NDMA) in direct-fire dried malt. NDMA levels in malt...
Publikováno v:
Analytical Chemistry. 51:2157-2159
Publikováno v:
Carcinogenesis. 5(10)
The carcinogenic activity of the 3-methyl derivative of nitroso-4-piperidone was compared with that of the compound without the methyl group, by chronic administration to rats at equimolar doses in drinking water. Nitrosopiperidone induced both liver