Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Mario Lobigs"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44834 (2012)
Japanese encephalitis is a severe central nervous system (CNS) inflammatory disease caused by the mosquito-borne flavivirus, Japanese encephalitis virus (JEV). In the current study we have investigated the immune responses against JEV in mice lacking
Externí odkaz:
https://doaj.org/article/dbae2c3ac1b14bd2900d0d3e628770bd
Autor:
Julián Pardo, Eva María Gálvez, Aulikki Koskinen, Markus M Simon, Mario Lobigs, Matthias Regner, Arno Müllbacher
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7512 (2009)
BACKGROUND: Ectromelia virus is a natural mouse pathogen, causing mousepox. The cytotoxic T (Tc) cell granule serine-protease, granzyme B, is important for its control, but the underlying mechanism is unknown. Using ex vivo virus immune Tc cells, we
Externí odkaz:
https://doaj.org/article/65498792f83d4665b5297cf371e14c8d
Autor:
Mohammed Alsharifi, Yoichi Furuya, Timothy R Bowden, Mario Lobigs, Aulikki Koskinen, Matthias Regner, Lee Trinidad, David B Boyle, Arno Müllbacher
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5336 (2009)
BACKGROUND: Influenza A (flu) virus causes significant morbidity and mortality worldwide, and current vaccines require annual updating to protect against the rapidly arising antigenic variations due to antigenic shift and drift. In fact, current subu
Externí odkaz:
https://doaj.org/article/d7df0ff886154443a74a919693951cdf
Autor:
Mario Lobigs, Arno Müllbacher, Aulikki Koskinen, Matthias Regner, Carolina R. Melo-Silva, David C. Tscharke
Publikováno v:
Virus Research. 228:61-65
Mousepox is caused by the orthopoxvirus ectromelia virus (ECTV), and is thought to be transmitted via skin abrasions. We studied the ECTV virulence factor N1 following subcutaneous infection of mousepox-susceptible BALB/c mice. In this model, ECTV la
Autor:
Maximilian Larena, Mario Lobigs
Publikováno v:
Virology. 506
The genetic basis for a dramatically increased virus susceptibility phenotype of MHC-II knockout mice acquired during routine maintenance of the mouse strain was determined. Segregation of the susceptibility allele from the defective MHC-II locus com
Publikováno v:
European Journal of Immunology. 43:1789-1798
Japanese encephalitis, caused by infection with the neurotropic flavivirus, Japanese encephalitis virus (JEV), is among the most important viral encephalitides in Asia. While previous studies established an essential role of Ab and type I IFN, it is
Autor:
Aulikki Koskinen, Carolina R. Melo-Silva, Mario Lobigs, David C. Tscharke, Arno Müllbacher, R. Mark L. Buller, Yik Chun Wong, Matthias Regner
Publikováno v:
Journal of Virology. 85:11170-11182
Ectromelia virus (ECTV) is a natural pathogen of mice that causes mousepox, and many of its genes have been implicated in the modulation of host immune responses. Serine protease inhibitor 2 (SPI-2) is one of these putative ECTV host response modifie
Autor:
J. Leung, Roy A. Hall, Mario Lobigs, Natalie A. Prow, Robert J. Hurrelbrink, David C. Clark, John S. Mackenzie, Peter C. McMinn, Fiona J. May, Alexander A. Khromykh, Daniel J. Westlake, Rebecca M. Biron
Publikováno v:
Journal of General Virology. 92:2286-2296
Murray Valley encephalitis virus (MVEV) is a mosquito-borne flavivirus endemic to Australia and Papua New Guinea. Most strains of MVEV cause potentially fatal cases of encephalitis in humans and horses, and have been shown to be highly neuroinvasive
Publikováno v:
Journal of Virology. 85:5446-5455
The immunological correlates for recovery from primary Japanese encephalitis virus (JEV) infection in humans and experimental animals remain poorly defined. To investigate the relative importance of the adaptive immune responses, we have established
Autor:
Aulikki Koskinen, Mario Lobigs, Mohammed Alsharifi, Matthias Regner, Arno Müllbacher, Yoichi Furuya
Publikováno v:
Journal of General Virology. 91:1450-1460
We have recently shown that intranasal (i.n.) administration of gamma-irradiated A/PR/8 [A/Puerto Rico/8/34 (H1N1)] protects mice against lethal avian influenza A/Vietnam/1203/2004 (H5N1) and other heterosubtypic influenza A infections. Here, we used