Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mario Kuttke"'
Autor:
Mario Kuttke, Dominika Hromadová, Ceren Yildirim, Julia S. Brunner, Andrea Vogel, Hannah Paar, Sophie Peters, Maria Weber, Melanie Hofmann, Martina Kerndl, Markus Kieler, Hannes Datler, Laszlo Musiejovsky, Manuel Salzmann, Michaela Lang, Klara Soukup, Angela Halfmann, Omar Sharif, Gernot Schabbauer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Aberrant innate immune responses to the gut microbiota are causally involved in the pathogenesis of inflammatory bowel diseases (IBD). The exact triggers and main signaling pathways activating innate immune cells and how they modulate adaptive immuni
Externí odkaz:
https://doaj.org/article/8fc40d72faab43029d584838fb78452a
Autor:
Diana Humer, Valentina Furlanetto, Anna-Katharina Schruef, Angelika Wlodarczyk, Mario Kuttke, Christina Divne, Oliver Spadiut
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 142, Iss , Pp 112037- (2021)
Fighting cancer still relies on chemo- and radiation therapy, which is a trade-off between effective clearance of malignant cells and severe side effects on healthy tissue. Targeted cancer treatment on the other hand is a promising and refined strate
Externí odkaz:
https://doaj.org/article/22b5b6fc624b4b9d9ae0f22e0dc7404f
Autor:
Klara Soukup, Angela Halfmann, Barbara Dillinger, Fiona Poyer, Katharina Martin, Bernadette Blauensteiner, Maximilian Kauer, Mario Kuttke, Gernot Schabbauer, Alexander M. Dohnal
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Maintaining dendritic cells (DC) in a state of dysfunction represents a key mechanism by which tumour cells evade recognition and elimination by the immune system. Limited knowledge about the intracellular mediators of DC dysfunction restric
Externí odkaz:
https://doaj.org/article/3fe0c65fdfaf40938ede05519f522fc0
Autor:
Romana Gugenberger, Alexander Dohnal, Kathrin Thell, Sarah Bischof, Mario Kuttke, Bernhard Peball, Hannes Muehleisen, Maria Urban, Andreas Tanzmann, Beate Pribitzer, Felix Batrina, Stefan Bunka, Sophia Spagl, Manuela Branka, Markus Raderer, Gerald Prager, Thorsten Fuereder, Nina Worel
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::323d591adb560e8848b2d43c36bd5603
https://doi.org/10.1136/jitc-2022-sitc2022.0722
https://doi.org/10.1136/jitc-2022-sitc2022.0722
Autor:
Romana Gugenberger, Alexander Dohnal, Andreas Tanzmann, Beate Pribitzer, Felix Batrina, Stefan Bunka, Sophia Spagl, Manuela Branka, Sarah Bischof, Kathrin Thell, Mario Kuttke, Maria Urban, Hannes Muehleisen, Bernhard Peball, Markus Raderer, Gerald Prager, Nina Worel
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94afcc28113a53093b2d7248ce77ee18
https://doi.org/10.1136/jitc-2022-sitc2022.0653
https://doi.org/10.1136/jitc-2022-sitc2022.0653
Autor:
James S. Wilmott, David Hoffmann, Richard A. Scolyer, Anais Elewaut, Kevin J. Harrington, Harriet Witthock, Johannes Zuber, Christian Umkehrer, Olivier Michielin, Maria Novatchkova, Tobias Neumann, Lukas Leiendecker, Sebastian Carotta, Thomas Wiesner, Sakari Vanharanta, Georgina V. Long, Anna C. Obenauf, Izabela Krecioch, Ines Pires da Silva, Camille L. Gerard, Lisa Haas, Michel A. Cuendet, Malin Pedersen, Mario Kuttke
Publikováno v:
Nature Cancer. 2:693-708
How targeted therapies and immunotherapies shape tumors, and thereby influence subsequent therapeutic responses, is poorly understood. In the present study, we show, in melanoma patients and mouse models, that when tumors relapse after targeted thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa35d79b5fecd0bb59068e383a0c837
https://doi.org/10.1038/s43018-021-00221-9
https://doi.org/10.1038/s43018-021-00221-9
Autor:
Mario Kuttke, Alexander Dohnal, Andreas Tanzmann, Beate Pribitzer, Felix Batrina, Stefan Bunka, Sophia Spagl, Manuela Branka, Sarah Bischof, Kathrin Thell, Maria Urban, Hannes Muehleisen, Bernhard Peball, Bianca Gapp, Angela Halfmann, Markus Raderer, Gerald Prager, Thorsten Fuereder, Romana Gugenberger, Nina Worel
Publikováno v:
Cancer Research. 83:LB187-LB187
Immune checkpoint control is one of several mechanisms that negatively influence the immune system and contribute to the development and progression of cancer. To enhance anti-tumor immune responses in patients with advanced solid tumors, we employ a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f77d9b734993dd9e5119fc18a9e3acaf
https://doi.org/10.1158/1538-7445.am2023-lb187
https://doi.org/10.1158/1538-7445.am2023-lb187
Autor:
Martina Kerndl, Alexander Hajto, Gernot Schabbauer, Paulina M. Dominiak, Mark A. Febbraio, Melanie Hofmann, Emma Estevez, Amanda E. Brandon, Andrea Vogel, Marta Kulik, Kristaps Klavins, Jörg Menche, Florian Gruber, Mario Kuttke, Lucia Quemada Garrido, Andreas Bergthaler, Ana Korosec, Casey L. Egan, Martina Schweiger, Alexander Lercher, Ildiko Mesteri, Thomas Weichhart, Marlene Pühringer, Omar Sharif, Maria W. Górna, Markus Kieler, Michael Caldera, Julia S. Brunner
Publikováno v:
Nature Metabolism. 2:1427-1442
Adipose tissue macrophages (ATMs) display tremendous heterogeneity depending on signals in their local microenvironment and contribute to the pathogenesis of obesity. The phosphoinositide 3-kinase (PI3K) signalling pathway, antagonized by the phospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8306c4ee964d4358ad251dcb66ac1636
https://doi.org/10.1038/s42255-020-00311-5
https://doi.org/10.1038/s42255-020-00311-5
Autor:
Christoph J. Binder, José Basílio, Bianca E. Suur, Florian Puhm, Maria J. Forteza, Viola Gleitsmann, Manuel Salzmann, Barbara Haigl, Daniel F. J. Ketelhuth, Mario Kuttke, Bernhard Hochreiter, Bastian Hoesel, Alice Assinger, Bernhard Moser, Caroline Ungerböck, Marion Mussbacher, Johannes A. Schmid
Publikováno v:
Atherosclerosis. 307:21-31
Background and aims Inflammatory activation of endothelial cells is considered to be the first step in the development of atherosclerosis. Here, we determined the consequences of chronic endothelial activation via the NF-κB activator Ikk2 (Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4398ad71d97c4d4a13ed9771b34c5a2
https://doi.org/10.1016/j.atherosclerosis.2020.06.005
https://doi.org/10.1016/j.atherosclerosis.2020.06.005
Autor:
Hannes Steinkellner, Prakasha Kempaiah, Alexander V. Beribisky, Sandra Pferschy, Julia Etzler, Anna Huber, Victoria Sarne, Winfried Neuhaus, Mario Kuttke, Jan Bauer, Jayamuruga P. Arunachalam, John Christodoulou, Ralf Dressel, Alexander Mildner, Marco Prinz, Franco Laccone
Publikováno v:
International journal of biological macromolecules. 209
Rett syndrome (RTT) is a neurodevelopmental disorder caused by pathogenic variants leading to functional impairment of the MeCP2 protein. Here, we used purified recombinant MeCP2e1 and MeCP2e2 protein variants fused to a TAT protein transduction doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4020cc67cbf55de8e9a68f6ba490c1ab
https://pubmed.ncbi.nlm.nih.gov/35460749
https://pubmed.ncbi.nlm.nih.gov/35460749