Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Mario Kaßmann"'
Autor:
Zhugang Chu, Mario Kassmann, Yoland-Marie Anistan, Friedrich C. Luft, Maik Gollasch, Dmitry Tsvetkov
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102845- (2024)
Summary: The isolated perfused kidney is a classic ex vivo preparation for studying renal physiology in general and vascular function. Here, we present a protocol for assessing myogenic tone in isolated mouse kidneys as well as vasodilatory and vasoc
Externí odkaz:
https://doaj.org/article/b9e16d014fee4a248769c6b4600eeb28
Autor:
Yingqiu Cui, Mario Kassmann, Sophie Nickel, Chenglin Zhang, Natalia Alenina, Yoland Marie Anistan, Johanna Schleifenbaum, Michael Bader, Donald G. Welsh, Yu Huang, Maik Gollasch
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Background Blood pressure and tissue perfusion are controlled in part by the level of intrinsic (myogenic) arterial tone. However, many of the molecular determinants of this response are unknown. We previously found that mice with targeted disruption
Externí odkaz:
https://doaj.org/article/2f2b387a1d25417a95ee41bf8a6174e8
Autor:
Yibin Wang, Fatima Yildiz, Andrey Struve, Mario Kassmann, Lajos Markó, May-Britt Köhler, Friedrich C. Luft, Maik Gollasch, Dmitry Tsvetkov
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Aging is an independent risk factor for hypertension, cardiovascular morbidity, and mortality. However, detailed mechanisms linking aging to cardiovascular disease are unclear. We studied the aging effects on the role of perivascular adipose tissue a
Externí odkaz:
https://doaj.org/article/31dd00349dd6488386695c75d383d9bd
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1–4, EHD2, pacsin2, and dynamin 2. Caveolae participate in several physiological pr
Externí odkaz:
https://doaj.org/article/53bd258f886645a6bbca46dd23965a8a
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Perivascular adipose tissue (PVAT) is implicated in the pathophysiology of cardiovascular disease, especially in obese individuals in which the quantity of renal and visceral PVAT is markedly increased. The control of arterial tone by PVAT has emerge
Externí odkaz:
https://doaj.org/article/1a694e30648645f58fdf783e1acaffe3
Autor:
Mario Kaßmann, István András Szijártó, Concha F. García‐Prieto, Gang Fan, Johanna Schleifenbaum, Yoland‐Marie Anistan, Christoph Tabeling, Yu Shi, Ferdinand le Noble, Martin Witzenrath, Yu Huang, Lajos Markó, Mark T. Nelson, Maik Gollasch
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 9 (2019)
Background Hypertension is the major risk factor for cardiovascular disease, the most common cause of death worldwide. Resistance arteries are capable of adapting their diameter independently in response to pressure and flow‐associated shear stress
Externí odkaz:
https://doaj.org/article/a9b9c6e3995a44efbfea4301b0b60f40
Autor:
Johannes Schmid, Bettina Müller, David Heppeler, Dina Gaynullina, Mario Kassmann, Hristo Gagov, Mitko Mladenov, Maik Gollasch, Rudolf Schubert
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 7 (2018)
BackgroundMultiple studies have shown that an NO‐induced activation of vascular smooth muscle BK channels contributes to the NO‐evoked dilation in many blood vessels. In vivo, NO is released continuously. NO attenuates vessel constrictions and, t
Externí odkaz:
https://doaj.org/article/872123e2413d44de8c19ad6f3361882a
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
The anti-contractile effect of perivascular adipose tissue (PVAT) is an important mechanism in the modulation of vascular tone in peripheral arteries. Recent evidence has implicated the XE991-sensitive voltage-gated Kv (KCNQ) channels in the regulati
Externí odkaz:
https://doaj.org/article/3f1b337cf24d4305abca6b3db96d2e4a
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109842 (2014)
OBJECTIVES: Transient receptor potential vanilloid 1 (TRPV1) -positive sensory nerves are widely distributed in the kidney, suggesting that TRPV1-mediated action may participate in the regulation of renal function under pathophysiological conditions.
Externí odkaz:
https://doaj.org/article/0b89ba0cd2b44bc28afc2e0a810babdf
Publikováno v:
Ageing research reviews. 84
The arterial myogenic response is an inherent property of resistance arteries. Myogenic tone is crucial for maintaining a relatively constant blood flow in response to changes in intraluminal pressure and protects delicate organs from excessive blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab37786860f4fb339cdbecc415347b64
https://pubmed.ncbi.nlm.nih.gov/36470339
https://pubmed.ncbi.nlm.nih.gov/36470339