Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mario J. Pace"'
Autor:
Craig H Warden, Ping Zi Wen, S. M. Shoemaker, Mario J. Pace, Janis S. Fisler, Karen L. Svenson, Aldons J. Lusis
Publikováno v:
Journal of Clinical Investigation. 95:1545-1552
We previously described a new mouse model for multigenic obesity, designated BSB. We now report the use of a complete linkage map approach to identify loci contributing to body fat and other traits associated with obesity in this model. Four loci exh
Publikováno v:
The Journal of clinical investigation. 92(2)
We have examined backcross progeny derived from a cross of Mus spretus with C57BL/6J, that range from 1 to 50% carcass lipid (n = 215), and from 22 to 130 mg/dl plasma total cholesterol (n = 238). Statistical analysis revealed that distal mouse chrom
Publikováno v:
Obesity research. 1(4)
We report here a new mouse model of multigenic obesity. Backcross progeny ((C57BL/6J x Mus spretus)F1 x C57BL/6J), designated as BSB mice, range from 1% to 50% body fat. Since both parental strains are relatively lean, the wide range of the phenotype