Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Mario Gomez-Salazar"'
Autor:
Ji-Hye Yea, Mario Gomez-Salazar, Sharon Onggo, Zhao Li, Neelima Thottappillil, Masnsen Cherief, Stefano Negri, Xin Xing, Qizhi Qin, Robert Joel Tower, Chen-Ming Fan, Benjamin Levi, Aaron W. James
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Heterotopic ossification (HO) is a pathological process resulting in aberrant bone formation and often involves synovial lined tissues. During this process, mesenchymal progenitor cells undergo endochondral ossification. Nonetheless, the spe
Externí odkaz:
https://doaj.org/article/812a270dd3d2487c96d53369d4a97c5e
Autor:
Qizhi Qin, Sowmya Ramesh, Mario Gomez-Salazar, Lingke Zhong, Masnsen Cherief, Aniket Pratapneni, Carol D. Morris, Edward F. McCarthy, Xinli Zhang, Aaron W. James
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-13 (2023)
Abstract Improved treatment strategies for sarcoma rely on clarification of the molecular mediators of disease progression. Recently, we reported that the secreted glycoprotein NELL-1 modulates osteosarcoma (OS) disease progression in part via alteri
Externí odkaz:
https://doaj.org/article/e9536b007196499980138c7321a006ae
Autor:
Qizhi Qin, Mario Gomez-Salazar, Masnsen Cherief, Chase A. Pagani, Seungyong Lee, Charles Hwang, Robert J. Tower, Sharon Onggo, Yuxiao Sun, Abhinav Piplani, Zhao Li, Sowmya Ramesh, Thomas L. Clemens, Benjamin Levi, Aaron W. James
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract The functional interdependence of nerves and blood vessels is a well-established concept during tissue morphogenesis, yet the role of neurovascular coupling in proper and aberrant tissue repair is an emerging field of interest. Here, we soug
Externí odkaz:
https://doaj.org/article/ef7282b1693d42e9be9a1347385481ec
Autor:
Alastair Morris Kilpatrick, Madalena Marques, Mario Gomez-Salazar, Dorota Stefancova, Diana Sá da Bandeira, Mihaela Crisan
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102016- (2023)
Summary: Mesenchymal stem/stromal cells (MSCs) can differentiate into osteoblasts under appropriate conditions. PDGFRβ signaling controls MSC osteogenic potential both transcriptomically and in culture. Here, we present a “computer to the bench”
Externí odkaz:
https://doaj.org/article/790df5f094ce4a84ade40fbc75d79b2e
Autor:
Charles D. Hwang, Chase A. Pagani, Johanna H. Nunez, Masnsen Cherief, Qizhi Qin, Mario Gomez-Salazar, Balram Kadaikal, Heeseog Kang, Ashish R. Chowdary, Nicole Patel, Aaron W. James, Benjamin Levi
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
Heterotopic ossification (HO) is the formation of ectopic bone that is primarily genetically driven (fibrodysplasia ossificans progressiva [FOP]) or acquired in the setting of trauma (tHO). HO has undergone intense investigation, especially over the
Externí odkaz:
https://doaj.org/article/d31528e030444c10bb1125fe02a37194
Publikováno v:
Journal of Innate Immunity, Pp 1-27 (2021)
Metabolic disorders, such as obesity, type 2 diabetes mellitus, and nonalcoholic fatty liver disease, are characterized by chronic low-grade tissue and systemic inflammation. During obesity, the adipose tissue undergoes immunometabolic and functional
Externí odkaz:
https://doaj.org/article/bbc6746ec11c46f095643e74b9e8e7ed
Autor:
Mario Gomez-Salazar, Zaniah N. Gonzalez-Galofre, Joan Casamitjana, Mihaela Crisan, Aaron W. James, Bruno Péault
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Mesenchymal stem cells are culture-derived mesodermal progenitors isolatable from all vascularized tissues. In spite of multiple fundamental, pre-clinical and clinical studies, the native identity and role in tissue repair of MSCs have long remained
Externí odkaz:
https://doaj.org/article/95b7c1ce7c9e465ea6d53ff0d96881fe
Autor:
Qizhi Qin, Seungyong Lee, Nirali Patel, Kalah Walden, Mario Gomez-Salazar, Benjamin Levi, Aaron W. James
Publikováno v:
Experimental & Molecular Medicine. 54:1844-1849
The mammalian skeletal system is densely innervated by both neural and vascular networks. Peripheral nerves in the skeleton include sensory and sympathetic nerves. The crosstalk between skeletal and neural tissues is critical for skeletal development
Autor:
Qizhi Qin, Mario Gomez-Salazar, Robert J. Tower, Leslie Chang, Carol D. Morris, Edward F. McCarthy, Kang Ting, Xinli Zhang, Aaron W. James
Publikováno v:
Cancer Res
Sarcomas produce an abnormal extracellular matrix (ECM), which in turn provides instructive cues for cell growth and invasion. Neural EGF like-like molecule 1 (NELL1) is a secreted glycoprotein characterized by its nonneoplastic osteoinductive effect
Autor:
Aaron W. James, Xinli Zhang, Kang Ting, Edward F. McCarthy, Carol D. Morris, Leslie Chang, Robert J. Tower, Mario Gomez-Salazar, Qizhi Qin
Sarcomas produce an abnormal extracellular matrix (ECM), which in turn provides instructive cues for cell growth and invasion. Neural EGF like-like molecule 1 (NELL1) is a secreted glycoprotein characterized by its nonneoplastic osteoinductive effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91afc340de0548b28c1fd8df6ac0af8
https://doi.org/10.1158/0008-5472.c.6514019
https://doi.org/10.1158/0008-5472.c.6514019