Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mario Garzilli"'
Autor:
Margherita Tassan Mazzocco, Claudia Pisanu, Luigi Russo, Clementina Acconcia, Marco Cambiaghi, Sofia De Girolamo, Alessio Squassina, Laura Cherchi, Elena Monzani, Francesca Scebba, Debora Angeloni, Danilo De Gregorio, Sofia Nasini, Stefano Dall’Acqua, Stefania Sut, Federico Suprani, Mario Garzilli, Beatrice Guiso, Vittoria Pulcinelli, Maria Novella Iaselli, Ilaria Pinna, Giulia Somaini, Laura Arru, Carolina Corrias, Pasquale Paribello, Federica Pinna, Gabriella Gobbi, Flavia Valtorta, Bernardo Carpiniello, Mirko Manchia, Stefano Comai
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 106993- (2023)
The treatment of bipolar disorder (BD) still remains a challenge. Melatonin (MLT), acting through its two receptors MT1 and MT2, plays a key role in regulating circadian rhythms which are dysfunctional in BD. Using a translational approach, we examin
Externí odkaz:
https://doaj.org/article/2266cc8d3b0c4df090ca73432daa27fa
Autor:
Pasquale Paribello, Alessio Squassina, Claudia Pisanu, Anna Meloni, Stefano Dall’Acqua, Stefania Sut, Sofia Nasini, Antonella Bertazzo, Donatella Congiu, Mario Garzilli, Beatrice Guiso, Federico Suprani, Vittoria Pulcinelli, Maria Novella Iaselli, Ilaria Pinna, Giulia Somaini, Laura Arru, Carolina Corrias, Federica Pinna, Bernardo Carpiniello, Stefano Comai, Mirko Manchia
Publikováno v:
Brain Sciences, Vol 13, Iss 4, p 693 (2023)
Background and Objectives: Alterations in hot cognition and in the tryptophan metabolism through serotonin (5-HT) and kynurenine (KYN) pathways have been associated with an increased risk of suicidal behavior. Here, we aim at probing the association
Externí odkaz:
https://doaj.org/article/2a9577058629418a92190c06341799c5
Autor:
Mirko Manchia, Alessio Squassina, Claudia Pisanu, Donatella Congiu, Mario Garzilli, Beatrice Guiso, Federico Suprani, Pasquale Paribello, Vittoria Pulcinelli, Maria Novella Iaselli, Federica Pinna, Flavia Valtorta, Bernardo Carpiniello, Stefano Comai
Publikováno v:
International Journal of Bipolar Disorders, Vol 7, Iss 1, Pp 1-7 (2019)
Abstract Background Bipolar disorder (BD) is characterized by recurrent episodes of depression and mania/hypomania alternating with intervals of well-being. The neurobiological underpinnings of BD are still veiled although there is evidence pointing
Externí odkaz:
https://doaj.org/article/4f8efa3b8cdd4fc58b8a146370fe6a78
Autor:
Claudia Pisanu, Alessio Squassina, Pasquale Paribello, Stefano Dall’Acqua, Stefania Sut, Sofia Nasini, Antonella Bertazzo, Donatella Congiu, Anna Meloni, Mario Garzilli, Beatrice Guiso, Federico Suprani, Vittoria Pulcinelli, Maria Novella Iaselli, Ilaria Pinna, Giulia Somaini, Laura Arru, Carolina Corrias, Federica Pinna, Bernardo Carpiniello, Stefano Comai, Mirko Manchia
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1127 (2022)
The kynurenine pathway (KP) may play a role in the pathophysiology of bipolar disorder (BD). We conducted a genome-wide association study (GWAS) to identify genetic variants associated with the plasma levels of the metabolites of tryptophan (TRP) via
Externí odkaz:
https://doaj.org/article/5861d6e5720f4fc6b9ffb742f93b32f1
Autor:
Frederike T. Fellendorf, Mirko Manchia, Alessio Squassina, Claudia Pisanu, Stefano Dall’Acqua, Stefania Sut, Sofia Nasini, Donatella Congiu, Eva Z. Reininghaus, Mario Garzilli, Beatrice Guiso, Federico Suprani, Pasquale Paribello, Vittoria Pulcinelli, Maria Novella Iaselli, Ilaria Pinna, Giulia Somaini, Laura Arru, Carolina Corrias, Federica Pinna, Bernardo Carpiniello, Stefano Comai
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 9, p 2517 (2022)
Bipolar disorder is associated with an inflammation-triggered elevated catabolism of tryptophan to the kynurenine pathway, which impacts psychiatric symptoms and outcomes. The data indicate that lithium exerts anti-inflammatory effects by inhibiting
Externí odkaz:
https://doaj.org/article/e513fa7ec9c843dcb77fee7b75909180
Autor:
Mirko Manchia, Andrea Fontana, Concetta Panebianco, Pasquale Paribello, Carlo Arzedi, Eleonora Cossu, Mario Garzilli, Maria Antonietta Montis, Andrea Mura, Claudia Pisanu, Donatella Congiu, Massimiliano Copetti, Federica Pinna, Valerio Pazienza, Alessio Squassina, Bernardo Carpiniello
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 875 (2021)
The gut microbiota is constituted by more than 40,000 bacterial species involved in key processes including high order brain functions. Altered composition of gut microbiota has been implicated in psychiatric disorders and in modulating the efficacy
Externí odkaz:
https://doaj.org/article/ce132ba8ce0047f6bf1d9829937c1c45
Autor:
Andrea Fontana, Mirko Manchia, Concetta Panebianco, Pasquale Paribello, Carlo Arzedi, Eleonora Cossu, Mario Garzilli, Maria Antonietta Montis, Andrea Mura, Claudia Pisanu, Donatella Congiu, Massimiliano Copetti, Federica Pinna, Bernardo Carpiniello, Alessio Squassina, Valerio Pazienza
Publikováno v:
Biomedicines, Vol 8, Iss 9, p 311 (2020)
Major depressive disorder (MDD) is a common severe psychiatric illness, exhibiting sub-optimal response to existing pharmacological treatments. Although its etiopathogenesis is still not completely understood, recent findings suggest that an altered
Externí odkaz:
https://doaj.org/article/6a334c3a02aa4c629b653cfbb67ba1c5
Autor:
Massimiliano Copetti, Pasquale Paribello, Alessio Squassina, Carlo Arzedi, Federica Pinna, E. Cossu, Donatella Congiu, Concetta Panebianco, Bernardo Carpiniello, Mirko Manchia, Andrea Mura, Maria Antonietta Montis, Valerio Pazienza, Mario Garzilli, Andrea Fontana, Claudia Pisanu
Publikováno v:
Biomedicines
Volume 9
Issue 8
Biomedicines, Vol 9, Iss 875, p 875 (2021)
Volume 9
Issue 8
Biomedicines, Vol 9, Iss 875, p 875 (2021)
The gut microbiota is constituted by more than 40,000 bacterial species involved in key processes including high order brain functions. Altered composition of gut microbiota has been implicated in psychiatric disorders and in modulating the efficacy
Autor:
Alessio Squassina, Maria Antonietta Montis, Pasquale Paribello, Carlo Arzedi, Claudia Pisanu, Donatella Congiu, Valerio Pazienza, Mario Garzilli, Andrea Mura, Andrea Fontana, Bernardo Carpiniello, Concetta Panebianco, Massimiliano Copetti, Federica Pinna, E. Cossu, Mirko Manchia
Publikováno v:
Biomedicines
Volume 8
Issue 9
Biomedicines, Vol 8, Iss 311, p 311 (2020)
Volume 8
Issue 9
Biomedicines, Vol 8, Iss 311, p 311 (2020)
Major depressive disorder (MDD) is a common severe psychiatric illness, exhibiting sub-optimal response to existing pharmacological treatments. Although its etiopathogenesis is still not completely understood, recent findings suggest that an altered
Autor:
Maria Antonietta Montis, Alessio Squassina, Valeria Sogos, Cristina Cocco, Andrea Mura, Anna Meloni, Roberta Vanni, Caterina Chillotti, Donatella Congiu, Renato Robledo, Giovanni Severino, Alberto Bocchetta, Raffaella Ardau, Maria Del Zompo, E. Cossu, Pasquale Paribello, Mario Garzilli, Barbara Noli, Gian-Luca Ferri, Tinuccia Dettori, Daniela Virginia Frau, Claudia Pisanu, Bernardo Carpiniello, Elias Manca, Paola Caria, Mirko Manchia, Federica Pinna, Carlo Arzedi, Mariella Nieddu
Publikováno v:
Neuropsychopharmacology
Individuals with severe psychiatric disorders have a reduced life expectancy compared to the general population. At the biological level, patients with these disorders present features that suggest the involvement of accelerated aging, such as increa