Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mario E. Valdés-Tresanco"'
Autor:
Mario S. Valdés-Tresanco, Mario E. Valdés-Tresanco, Marcela Rubio-Carrasquilla, Pedro A. Valiente, Ernesto Moreno
Publikováno v:
ACS Omega, Vol 6, Iss 44, Pp 29525-29536 (2021)
Externí odkaz:
https://doaj.org/article/063c7acfcb8b4e69ad866ca3c58c6cd1
Autor:
David Kerk, Jordan F. Mattice, Mario E. Valdés-Tresanco, Sergei Yu Noskov, Kenneth K.-S. Ng, Greg B. Moorhead
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Phosphoprotein phosphatase (PPP) enzymes are ubiquitous proteins involved in cellular signaling pathways and other functions. Here we have traced the origin of the PPP sequences of Eukaryotes and their radiation. Using a bacterial PPP Hidden
Externí odkaz:
https://doaj.org/article/3b06f50c4dba434391b0f94c6280040b
Autor:
Mario S. Valdés-Tresanco, Mario E. Valdés-Tresanco, Daiver E. Jiménez-Gutiérrez, Ernesto Moreno
Publikováno v:
Molecules, Vol 28, Iss 10, p 3991 (2023)
The number of applications for nanobodies is steadily expanding, positioning these molecules as fast-growing biologic products in the biotechnology market. Several of their applications require protein engineering, which in turn would greatly benefit
Externí odkaz:
https://doaj.org/article/4feb95bf4c694153a07c3b6924ed83b5
Publikováno v:
Biology Direct, Vol 15, Iss 1, Pp 1-12 (2020)
Abstract AMDock (Assisted Molecular Docking) is a user-friendly graphical tool to assist in the docking of protein-ligand complexes using Autodock Vina and AutoDock4, including the option of using the Autodock4Zn force field for metalloproteins. AMDo
Externí odkaz:
https://doaj.org/article/654a5f00579b4108a035890672948eb3
Autor:
David Kerk, Mario E. Valdés-Tresanco, Ryan Toth, Sergei Yu. Noskov, Kenneth K.-S. Ng, Greg B. Moorhead
Publikováno v:
BBA Advances, Vol 1, Iss , Pp 100005- (2021)
Background: Phosphoprotein phosphatases (PPP) belong to the PPP Sequence family, which in turn belongs to the broader metallophosphoesterase (MPE) superfamily. The relationship between the PPP Sequence family and other members of the MPE superfamily
Externí odkaz:
https://doaj.org/article/de6d77dcf5ea48508a1691d8b862e2d7
Publikováno v:
The Journal of Physical Chemistry B. 127:944-954
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::023202a077e59e48ba50db6f9488ed0b
https://doi.org/10.1021/acs.jpcb.2c07079
https://doi.org/10.1021/acs.jpcb.2c07079
Autor:
Yarini Arrebola Sánchez, Fabiola Almeida García, Daniel Ojeda del Sol, Mario E. Valdés-Tresanco, Carlos David Ortiz, Belinda Sánchez Ramírez, Isel Pascual Alonso
Publikováno v:
Physical Sciences Reviews.
Ectopeptidases are particularly interesting due to their potential to regulate/dysregulate the peptide mediated signaling cellular pathways because the active site located to the extracellular space. Dipeptidyl peptidase IV (DPP-IV, EC 3.4.14.5) is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14425a4eb3077127cfd57334a6a9c818
https://doi.org/10.1515/psr-2022-0288
https://doi.org/10.1515/psr-2022-0288
Publikováno v:
Database. 2023
We present NbThermo—a first-in-class database that collects melting temperatures (Tm), amino acid sequences and several other categories of useful data for hundreds of nanobodies (Nbs), compiled from an extensive literature search. This so-far uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3097ac086504dfb8b12ace35221e00a1
https://doi.org/10.1093/database/baad021
https://doi.org/10.1093/database/baad021
Autor:
Pedro A. Valiente, Marcela Rubio-Carrasquilla, Ernesto Moreno, Mario S. Valdés-Tresanco, Mario E. Valdés-Tresanco
Publikováno v:
ACS Omega, Vol 6, Iss 44, Pp 29525-29536 (2021)
ACS Omega
ACS Omega
Vps34 is the only isoform of the PI3K family in fungi, making this protein an attractive target to develop new treatments against pathogenic fungi. The high structural similarity between the active sites of the human and fungal Vps34 makes repurposin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bb032af25218e37602cb7138486519
https://doaj.org/article/063c7acfcb8b4e69ad866ca3c58c6cd1
https://doaj.org/article/063c7acfcb8b4e69ad866ca3c58c6cd1
Publikováno v:
Journal of Chemical Theory and Computation. 17:6281-6291
Molecular mechanics/Poisson-Boltzmann (Generalized-Born) surface area is one of the most popular methods to estimate binding free energies. This method has been proven to balance accuracy and computational efficiency, especially when dealing with lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa082b426183d3655b4d99db485bd314
https://doi.org/10.1021/acs.jctc.1c00645
https://doi.org/10.1021/acs.jctc.1c00645