Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mario Dipaola"'
Autor:
Mahesh Koirala, Mario DiPaola
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 1713-1730 (2024)
The persistent threat of cancer remains a significant hurdle for global health, prompting the exploration of innovative approaches in the quest for successful therapeutic interventions. Cyclin-dependent kinase 9 (CDK9), a central player in transcript
Externí odkaz:
https://doaj.org/article/f783286520344c43ac6d38cb2adfc5ad
Autor:
Mahesh Koirala, Mario DiPaola
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1801 (2024)
Resistance to cancer drugs is a complex phenomenon that poses a significant challenge in the treatment of various malignancies. This review comprehensively explores cancer resistance mechanisms and discusses emerging strategies and modalities to over
Externí odkaz:
https://doaj.org/article/5535ea3c7c7d46dab378ce2791594e05
Autor:
Shivalika Tanwar, Patrick Auberger, Germain Gillet, Mario DiPaola, Katya Tsaioun, Bruno O. Villoutreix
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108159- (2022)
Drug discovery often requires the identification of off-targets as the binding of a compound to targets other than the intended target(s) can be beneficial in some cases or detrimental in other situations (e.g., binding to anti-targets). Such investi
Externí odkaz:
https://doaj.org/article/6e535296d326447eb4efea2ac8a595bb
Autor:
Mario DiPaola
Publikováno v:
Journal of Bioanalysis & Biomedicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8094d559275fb10131ee6000d19a60e
https://doi.org/10.4172/1948-593x.c1.022
https://doi.org/10.4172/1948-593x.c1.022
Publikováno v:
Journal of Bioanalysis & Biomedicine.
Experimentally, the analysis of N- and O-linked glycosylation typically starts with the release of the glycans by enzymatic or chemical means, followed by derivatization and then chromatographic separation with in line mass spectroscopy for relative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663459bf528ba42edd18ce5b245ed80a
https://doi.org/10.4172/1948-593x.1000096
https://doi.org/10.4172/1948-593x.1000096
Publikováno v:
Pathobiology. 63:168-174
Twenty-two rabbits received Torpedo californica acetylcholine receptor (AChR) subcutaneously. Six rabbits were treated with 0.5 ml/kg/day of anti-rabbit thymocyte serum (ARTS), and four were treated with 5.0 mg/kg/day of anti-rabbit thymocyte gammagl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744e01ec7127ca6fab7f1328953c20df
https://doi.org/10.1159/000163948
https://doi.org/10.1159/000163948
Publikováno v:
Journal of Interferon Research. 14:325-332
Peripheral blood leukocytes, isolated from the buffy coats of greater than 10,700 normal healthy donors, were induced with Sendai virus to produce biologically active interferon alpha (IFN-alpha). The IFN-alpha was purified to near homogeneity by imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca82875b03e92e0e06cb6b4527e48278
https://doi.org/10.1089/jir.1994.14.325
https://doi.org/10.1089/jir.1994.14.325
Autor:
K. Ferencz-Biro, Douglas Testa, T. Smith, Mario Dipaola, D. Ni, Mei-June Liao, M. Hussain, N. Lee, M. Desai, R. Brissette
Publikováno v:
Journal of Interferon Research. 14:183-185
In the normal course of a viral infection, human cells produce interferons (IFNs) as the first line of defense. These IFNs differ depending upon the cells and the nature of the infecting virus. Over the past 20 years it has become clear that there ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d6c3d70e81fcf06c4d1d6ac83b8042
https://doi.org/10.1089/jir.1994.14.183
https://doi.org/10.1089/jir.1994.14.183
Publikováno v:
Annals of the New York Academy of Sciences. 421:424-433
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2018e897e601306c8acd9a9b55e1b3
https://doi.org/10.1111/j.1749-6632.1983.tb18136.x
https://doi.org/10.1111/j.1749-6632.1983.tb18136.x
Autor:
Mario Dipaola, Frederick R. Maxfield
Publikováno v:
Journal of Biological Chemistry. 259:9163-9171
We have used a variety of methods, including lactoperoxidase-catalyzed iodination, proteolysis, and photolabel incorporation, to determine whether exposure to the acidic pH encountered during receptor-mediated endocytosis causes observable conformati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::403163641c3ac19a0bc49b554ccbf291
https://doi.org/10.1016/s0021-9258(17)47279-6
https://doi.org/10.1016/s0021-9258(17)47279-6