Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mario D. Garcia"'
Autor:
Thierry Lonhienne, Yan Cheng, Mario D. Garcia, Shu Hong Hu, Yu Shang Low, Gerhard Schenk, Craig M. Williams, Luke W. Guddat
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Acetohydroxyacid synthase (AHAS) is the target of more than 50 commercial herbicides, with many site-of-action resistance isolates identified in weeds. Here, the authors report the structural and kinetic characterizations to explain the effect AHAS m
Externí odkaz:
https://doaj.org/article/68f3e1fade02483b9c5675527dfc23aa
Autor:
Maria Eduarda Sevilla, Mario D. Garcia, Yunierkis Perez-Castillo, Vinicio Armijos-Jaramillo, Santiago Casado, Karla Vizuete, Alexis Debut, Liliana Cerda-Mejía
Publikováno v:
Polymers, Vol 15, Iss 7, p 1779 (2023)
Extensive plastic production has become a serious environmental and health problem due to the lack of efficient treatment of plastic waste. Polyethylene terephthalate (PET) is one of the most used polymers and is accumulating in landfills or elsewher
Externí odkaz:
https://doaj.org/article/684489e1ec594a74b0523e1d0080c7a8
Autor:
Yan Cheng, Thierry Lonhienne, Mario. D. Garcia, Craig M. Williams, Gerard Schenk, Luke W. Guddat
Publikováno v:
Journal of Agricultural and Food Chemistry. 71:5117-5126
Autor:
James A. Fraser, Gerhard Schenk, Quan Wang, Michael J. Landsberg, Zihe Rao, Luke W. Guddat, Craig M. Williams, Yu shang Low, Thierry G. A. Lonhienne, Lou Brillault, Ross P. McGeary, Nicholas P. West, Tristan I. Croll, Mario D. Garcia, Yan Gao
Publikováno v:
Nature. 586:317-321
Acetohydroxyacid synthase (AHAS), also known as acetolactate synthase, is a flavin adenine dinucleotide-, thiamine diphosphate- and magnesium-dependent enzyme that catalyses the first step in the biosynthesis of branched-chain amino acids1. It is the
Autor:
Mario D. Garcia, James A. Fraser, Gerhard Schenk, Luke W. Guddat, Yu shang Low, Thierry G. A. Lonhienne
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Aspergillus fumigatus is a fungal pathogen whose effects can be debilitating and potentially fatal in immunocompromised patients. Current drug treatment options for this infectious disease are limited to just a few choices (e.g. voriconazole and amph
Autor:
Thierry, Lonhienne, Yu Shang, Low, Mario D, Garcia, Tristan, Croll, Yan, Gao, Quan, Wang, Lou, Brillault, Craig M, Williams, James A, Fraser, Ross P, McGeary, Nicholas P, West, Michael J, Landsberg, Zihe, Rao, Gerhard, Schenk, Luke W, Guddat
Publikováno v:
Nature. 586(7828)
Acetohydroxyacid synthase (AHAS), also known as acetolactate synthase, is a flavin adenine dinucleotide-, thiamine diphosphate- and magnesium-dependent enzyme that catalyses the first step in the biosynthesis of branched-chain amino acids
Autor:
Mario D. Garcia, Jeffrey Harmer, James A. Fraser, Christopher J. Noble, Craig M. Williams, Luke W. Guddat, Thierry G. A. Lonhienne
Publikováno v:
ChemistrySelect. 2:11981-11988
Acetohydroxyacid synthase (AHAS) is the first enzyme in the biosynthesis pathway of the branched-chain amino acids, catalyzing the condensation of pyruvate with another molecule of pyruvate or with 2-ketobutyrate, to produce 2-acetolactate or 2-aceto
Publikováno v:
The FEBS Journal. 284:2037-2051
Acetohydroxyacid synthase (AHAS, EC 2.2.1.6) is the first enzyme in the branched-chain amino acid biosynthesis pathway. Five of the most widely used commercial herbicides (i.e. sulfonylureas, imidazolinones, triazolopyrimidines, pyrimidinyl-benzoates
Publikováno v:
Journal of Biological Chemistry. 292:5101-5109
Acetohydroxyacid synthase (AHAS) catalyzes the first step of branched-chain amino acid (BCAA) biosynthesis, a pathway essential to the lifecycle of plants and microorganisms. This enzyme is of high interest because its inhibition is at the base of th
Autor:
Shan Zheng, Khushboo M. Patel, Ross P. McGeary, Mark A. Schembri, David Terán, Luke W. Guddat, Ajit Kandale, Gerhard Schenk, You Lv, Mario D. Garcia
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 23(72)
Ketol-acid reductoisomerase (KARI) is an NAD(P)H and Mg2+-dependent enzyme of the branched-chain amino acid (BCAA) biosynthesis pathway. Here we describe the first crystal structures of Staphylococcus aureus (Sa) KARI, these in complex with two trans