Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Mario Chojkier"'
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0169310 (2017)
BACKGROUND:Recently, a complex microbiome was comprehensibly characterized in the serum and ascitic fluid of cirrhotic patients. In the current study, we investigated for the first time the induction of inflammatory pathways and Nitric Oxide, as well
Externí odkaz:
https://doaj.org/article/450fab4ecd4a4348a05f0e98aafc38e1
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31516 (2012)
Insulin resistance (IR) is induced by chronic hepatitis C virus (HCV) genotypes 1 and 4 infections. It is not known whether drugs that affect IR such as Pioglitazone and Prednisone also affect serum HCV RNA titers independently of PEG-Interferon-α2/
Externí odkaz:
https://doaj.org/article/e7104214705a4262b542e8d212056418
Autor:
Martina Buck, Mario Chojkier
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25497 (2011)
BackgroundAlthough C/EBPβ(ko) mice are refractory to Bleomycin-induced lung fibrosis the molecular mechanisms remain unknown. Here we show that blocking the ribosomal S-6 kinase (RSK) phosphorylation of the CCAAT/Enhancer Binding Protein (C/EBP)-β
Externí odkaz:
https://doaj.org/article/26ff81521fb44180a45dfa8f421ebbc0
Autor:
Martina Buck, Mario Chojkier
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1372 (2007)
BACKGROUND: In response to liver injury, hepatic stellate cell (HSC) activation causes excessive liver fibrosis. Here we show that activation of RSK and phosphorylation of C/EBPbeta on Thr217 in activated HSC is critical for the progression of liver
Externí odkaz:
https://doaj.org/article/10d0c62866dd4b2ab68c22756c77605c
Publikováno v:
Journal of Gastroenterology and Hepatology Research. 5:2173-2179
AIM: Hepatitis C virus (HCV) infection in patients induces hepatocyte proliferation and also hepatocellular carcinoma. The mechanisms and the liver acinar distribution of the HCV infection remain unclear. The aim of this study was to determine the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a61d4de20fd79d71e2d2cc8da7c878a2
https://doi.org/10.17554/j.issn.2224-3992.2016.05.657
https://doi.org/10.17554/j.issn.2224-3992.2016.05.657
Publikováno v:
Immunochemistry of the Extracellular Matrix ISBN: 9781351073424
This chapter covers all aspects of experiments designed to measure the rate of collagen synthesis in whole animals, isolated tissues, or cell cultures. It describes methods to determine the relative and absolute rates of collagen synthesis and the ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ee5befaf6fae841c3d782dc0e72f05
https://doi.org/10.1201/9781351073424-2
https://doi.org/10.1201/9781351073424-2
Autor:
Mario Chojkier
Publikováno v:
Acta Gastroenterológica Latinoamericana, Vol 38, Iss 4, p 309 (2008)
Externí odkaz:
https://doaj.org/article/df21ec9d9fc94e29af551177a213cf3e
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0169310 (2017)
PLoS ONE
PLoS ONE
Background Recently, a complex microbiome was comprehensibly characterized in the serum and ascitic fluid of cirrhotic patients. In the current study, we investigated for the first time the induction of inflammatory pathways and Nitric Oxide, as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ed0c025dffd73afa3b0811ed90b9dd
http://europepmc.org/articles/PMC5287452?pdf=render
http://europepmc.org/articles/PMC5287452?pdf=render
Autor:
Mario Chojkier, David Patch, Andrew K. Burroughs, Norman D. Grace, Guadalupe Garcia-Tsao, Roberto J. Groszmann, Paul Clopton, Martina Buck, Daniel S. Matloff, Caitlin Stalling
Publikováno v:
Hepatology. 59:1052-1059
The rationale for screening inflammatory serum biomarkers of the hepatic vein pressure gradient (HVPG) is based on the fact that portal hypertension is pathogenically related to liver injury and fibrosis, and that in turn these are associated with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8acb0ecc19be33c93853426faabd75
https://doi.org/10.1002/hep.26755
https://doi.org/10.1002/hep.26755
Publikováno v:
Scientific Reports
Amplification of liver injury is mediated by macrophages but the signaling by which the macrophage inflammasome enhances liver injury is not completely understood. The CCAAT/Enhancer Binding Protein-β (C/EBPβ) is a critical signaling molecule for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649f69a036653a1dbd7f8fe794739b3c