Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mario Canki"'
Autor:
Elena E Paskaleva, Manoj Arra, Yanze Liu, Huijun Guo, Glenn Swartz, Jeffrey S Kennedy, Curt Breneman, Alexander Shekhtman, Mario Canki
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93108 (2014)
AIDS is a global pandemic that has seen the development of novel and effective treatments to improve the quality of life of those infected and reduction of spread of the disease. Palmitic Acid (PA), which we identified and isolated from Sargassum fus
Externí odkaz:
https://doaj.org/article/f779ad529edd4f41a12d09b20e98bf7f
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24803 (2011)
Approximately 80% of all new HIV-1 infections are acquired through sexual contact. Currently, there is no clinically approved microbicide, indicating a clear and urgent therapeutic need. We recently reported that palmitic acid (PA) is a novel and spe
Externí odkaz:
https://doaj.org/article/0f23dcb0660e42b2a51efe937788f851
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12168 (2010)
We recently reported that palmitic acid (PA) is a novel and efficient CD4 fusion inhibitor to HIV-1 entry and infection. In the present report, based on in silico modeling of the novel CD4 pocket that binds PA, we describe discovery of highly potent
Externí odkaz:
https://doaj.org/article/b6335280d0c84839803b150a8ece5ec7
Autor:
Daniele Fabris, Clare M. Miller, Mario Canki, Jason M. Biegel, Manoj Arra, Rachel Netzband, Gaston Bonenfant, Cara T. Pager, Will McIntyre, Eric Henderson, Gabriele Fuchs
Publikováno v:
Nucleic Acids Research
More than 140 post-transcriptional modifications (PTMs) are known to decorate cellular RNAs, but their incidence, identity and significance in viral RNA are still largely unknown. We have developed an agnostic analytical approach to comprehensively s
Autor:
Hui-jun Guo, Jeffrey S. Kennedy, Alexander Shekhtman, Elena E. Paskaleva, Yanze Liu, Manoj Arra, Mario Canki
Publikováno v:
Chinese Herbal Medicines. 6:265-273
AIDS is a global pandemic that has seen the development of novel and effective treatments to improve the quality of life of those infected and reduction in the spread of the disease. While great advancements have been made in HIV/AIDS therapeutics, t
Autor:
Zhuying Wang, Gusta Trillo-Pazos, Seon-Young Kim, Mario Canki, Susan Morgello, Leroy Sharer, Harris Gelbard, Zao-zhong Su, Dong-chul Kang, Andrew Brooks, Paul Fisher, David Volsky
Publikováno v:
Journal of NeuroVirology. 10:25-32
Autor:
Elena Paskaleva, Xudong Lin, Wen Li, Robin Cotter, Michael Klein, Emily Roberge, Er Yu, Bruce Clark, Jean-Claude Veille, Yanze Liu, David Lee, Mario Canki
Publikováno v:
Recent Advances in Plant-Based, Traditional, and Natural Medicines ISBN: 9781771880138
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e475cb47d7a07e68bece24f0922354
https://doi.org/10.1201/b16611-14
https://doi.org/10.1201/b16611-14
Autor:
Mary Jane Potash, David J. Volsky, Mario Canki, Janice Ngee Foong Thai, Anuja Ghorpade, Wei Chao
Publikováno v:
Journal of Virology. 75:7925-7933
Human astrocytes can be infected with human immunodeficiency virus type 1 (HIV-1) in vitro and in vivo, but, in contrast to T lymphocytes and macrophages, virus expression is inefficient. To investigate the HIV-1 life cycle in human fetal astrocytes,
Publikováno v:
AIDS Research and Human Retroviruses. 16:453-463
Human immunodeficiency virus type 1 (HIV-1) has been found in the vitreous of persons with AIDS. Here we investigated the susceptibility of human retinal pigment epithelial (RPE) cells to HIV-1 infection in culture and the effects of HIV-1 on the pha
Autor:
Murk-Hein Heinemann, Harris A. Gelbard, David J. Volsky, Flynn Te, Wei Chao, Galina Bentsman, Mario Canki, Mary Jane Potash
Publikováno v:
Europe PubMed Central
Vitreous specimens from 14 HIV-1 infected persons undergoing medically indicated vitrectomy were assayed for the presence of infectious HIV-1 and viral tropism. Human primary fetal astrocytes, adult lymphocytes, or macrophages were exposed to vitreou