Differentiation of human iPSCs into functional podocytes.

Autor: Caroline Rauch, Elisabeth Feifel, Georg Kern, Cormac Murphy, Florian Meier, Walther Parson, Mario Beilmann, Paul Jennings, Gerhard Gstraunthaler, Anja Wilmes

Publikováno v: PLoS ONE, Vol 13, Iss 9, p e0203869 (2018)

Podocytes play a critical role in glomerular barrier function, both in health and disease. However, in vivo terminally differentiated podocytes are difficult to be maintained in in vitro culture. Induced pluripotent stem cells (iPSCs) offer the uniqu

Externí odkaz: https://doaj.org/article/325eb63f76db45778a8dc35f520f2e33

Development of an in silico consensus model for the prediction of the phospholipigenic potential of small molecules

Autor: Sebastian Schieferdecker, Andreas Eberlein, Esther Vock, Mario Beilmann

Publikováno v: Computational Toxicology. 22:100226

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2cc393c2ce8ad3667bb8ecc6f1e82f2b
https://doi.org/10.1016/j.comtox.2022.100226

Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data

Autor: Julia Hoeng, Joëlle Rüegg, Costanza Rovida, Matthias Herzler, Sofia B. Leite, Barry Hardy, Thomas Steger-Hartmann, Sandra Coecke, Francois Busquet, Thomas Exner, Barbara M.A. van Vugt-Lussenburg, Mirjam Luijten, Janine Ezendam, Jan G. Hengstler, Florian Gantner, Tanja Waldmann, Susanne Hougaard Bennekou, Kristina Fant, Bart van der Burg, Alice Krebs, Marcel Leist, Daniel R. Dietrich, Albert Braeuning, Ellen Fritsche, Emma Pedersen, Giorgia Pallocca, Tuula Heinonen, Mario Beilmann, Andrea Terron, Philip Hewitt, Thomas Hartung, Olesja Bondarenko, Stefan Kustermann, Hennicke Kamp, Torsten R. Dunkern, Martin F. Wilks

Publikováno v: Krebs, A, Waldmann, T, Wilks, M F, Van Vugt-Lussenburg, B M A, Van der Burg, B, Terron, A, Steger-Hartmann, T, Ruegg, J, Rovida, C, Pedersen, E, Pallocca, G, Luijten, M, Leite, S B, Kustermann, S, Kamp, H, Hoeng, J, Hewitt, P, Herzler, M, Hengstler, J G, Heinonen, T, Hartung, T, Hardy, B, Gantner, F, Fritsche, E, Fant, K, Ezendam, J, Exner, T, Dunkern, T, Dietrich, D R, Coecke, S, Busquet, F, Braeuning, A, Bondarenko, O, Hougaard Bennekou, S, Beilmann, M & Leist, M 2020, ' Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data ', A L T E X. Alternatives to Animal Experimentation, vol. 37, no. 1, pp. 164-164 . https://doi.org/10.14573/altex.1909271e

Only few cell-based test methods are described by Organisation for Economic Co-operation and Development (OECD) test guidelines or other regulatory references (e.g., the European Pharmacopoeia). The majority of toxicity tests still falls into the cat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17547a120d82232053cfcea5a885530
https://orbit.dtu.dk/en/publications/07a9a3c2-fd15-408a-a12a-cade067fb4c2

Evaluating the Effect of Drug Compounds on Cardiac Spheroids Using the Cardiac Cell Outgrowth Assay

Autor: Jonas, Christoffersson, Florian, Meier, Henning, Kempf, Kristin, Schwanke, Michelle, Coffee, Mario, Beilmann, Robert, Zweigerdt, Carl-Fredrik, Mandenius

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1994

The ideal cell culture model should mimic the cell physiology and the mechanical and the chemical cues that are present in specific tissues and organs, within a convenient high-throughput format. A possible key feature for such models is to recapture

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a68828f364be07038cd87c8635867121
https://pubmed.ncbi.nlm.nih.gov/31124116

https://www.altex.org/index.php/altex/article/view/1339

Autor: Alice Krebs, Tanja Waldmann, Martin F. Wilks, Barbara M. A. van Vugt-Lussenburg, Bart van der Burg, Andrea Terron, Thomas Steger-Hartmann, Joelle Ruegg, Costanza Rovida, Emma Pedersen, Giorgia Pallocca, Mirjam Luijten, Sofia B. Leite, Stefan Kustermann, Hennicke Kamp, Julia Hoeng, Philip Hewitt, Matthias Herzler, Jan G. Hengstler, Tuula Heinonen, Thomas Hartung, Barry Hardy, Florian Gantner, Ellen Fritsche, Kristina Fant, Janine Ezendam, Thomas Exner, Torsten Dunkern, Daniel R. Dietrich, Sandra Coecke, Francois Busquet, Albert Braeuning, Olesja Bondarenko, Susanne H. Bennekou, Mario Beilmann, Marcel Leist

Publikováno v: ALTEX

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb6c6416ad6a2de566c400479e5f185