Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mario A. J. A. Hermsen"'
Autor:
Sarah Derks, Cindy Postma, Peter T. M. Moerkerk, Sandra M. van den Bosch, Beatriz Carvalho, Mario A. J. A. Hermsen, Walter Giaretti, James G. Herman, Matty P. Weijenberg, Adriaan P. de Bruïne, Gerrit A. Meijer, Manon van Engeland
Publikováno v:
Cellular Oncology, Vol 28, Iss 5-6, Pp 247-257 (2006)
Background: Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship with mutations and chromosomal alterations in colorectal carcinogenesis. Methods:
Externí odkaz:
https://doaj.org/article/6197e484961441bebbc8ce10a2d9e3e8
Autor:
Donatella Santini, Gerrit A. Meijer, Fulvia Farabegoli, Marianne M Weiss, Mario A J A Hermsen, Paul J. van Diest, Claudio Ceccarelli
Publikováno v:
Farabegoli, F, Hermsen, M A J A, Ceccarelli, C, Santini, D, Weiss, M M, Meijer, G A & van Diest, P J 2004, ' Simultaneous chromosome 1q gain and 16q loss is associated with steroid receptor presence and low proliferation in breast carcinoma. ', Modern Pathology, vol. 17, no. 4, pp. 449-55 . https://doi.org/10.1038/modpathol.3800059
Modern Pathology, 17(4), 449-55. Nature Publishing Group
Modern Pathology, 17(4), 449-55. Nature Publishing Group
We applied comparative genomic hybridization (CGH) to 46 breast carcinoma samples, collected from 1993 to 1995, in order to detect chromosome 1q gains and 16q losses and to define whether samples showing both these alterations had distinct biopatholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a113f3c1df0fbe9dfeb8ba746f012c48
https://doi.org/10.1038/modpathol.3800059
https://doi.org/10.1038/modpathol.3800059
Autor:
Mehdi Jiwa, Mario A. J. A. Hermsen, Emiel A. M. Janssen, Paul J. van Diest, Jan P. A. Baak, Marta Alonso Guervós
Publikováno v:
The Journal of Pathology. 201:555-561
0.0001). Cox regression revealed that the 3q gain was the strongest prognostic factor; other features did not have additional prognostic value. In conclusion, loss of 1p is associated with a high MAI. A gain of 3q is a stronger predictor of recurrenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f2b11e21301563cdff06c06bac7f17e
https://doi.org/10.1002/path.1475
https://doi.org/10.1002/path.1475
Autor:
Ronald P. Zweemer, Mario A. J. A. Hermsen, Antoine M. Snijders, Peter Kenemans, René H.M. Verheijen, Paul J. van Diest, Jan P. A. Baak, Andy Ryan, Fred H. Menko, Ian Jacobs, Uziel Beller, Gerrit A. Meijer
Publikováno v:
Laboratory Investigation. 81:1363-1370
The vast majority of familial ovarian cancers harbor a germline mutation in either the breast cancer gene BRCA1 or BRCA2 tumor suppressor genes. However, mutations of these genes in sporadic ovarian cancer are rare. This suggests that in contrast to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407b5a6b42a6ea5b529e743aea2288ac
https://doi.org/10.1038/labinvest.3780350
https://doi.org/10.1038/labinvest.3780350
Autor:
Jan P. A. Baak, Ger H. A. Scholte, Gerrit A. Meijer, Marjan M. Weiss, Nicole C.T. van Grieken, Ernst J. Kuipers, Elisabeth Bloemena, M. E. Craanen, Jan H.N. Lindeman, Stefan G. M. Meuwissen, Mario A. J. A. Hermsen
Publikováno v:
Van Grieken, N C T, Weiss, M M, Meijer, G A, Hermsen, M A J A, Scholte, G H A, Lindeman, J, Craanen, M E, Bloemena, E, Meuwissen, S G M, Baak, J P A & Kuipers, E J 2000, ' Helicobacter pylori-related and-non-related gastric cancers do not differ with respect to chromosomal aberrations ', Journal of Pathology, vol. 192, no. 3, pp. 301-306 . https://doi.org/10.1002/1096-9896(2000)9999:9999<::AID-PATH697>3.0.CO;2-F
Journal of Pathology, 192(3), 301-306. John Wiley and Sons Ltd
Journal of Pathology, 192(3), 301-306. John Wiley and Sons Ltd
Gastric carcinogenesis is strongly associated with Helicobacter pylori infection, but the underlying genetic mechanisms are largely unknown. The aim of this study was to correlate chromosomal aberrations in gastric cancer to H. pylori status and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b59bf622a3c53505f7240da6b556ad
http://www.scopus.com/inward/record.url?scp=0033650608&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=0033650608&partnerID=8YFLogxK
Publikováno v:
Journal of Pathology, 189, 338-343. John Wiley and Sons Ltd
Torenbeek, R, Hermsen, M A J A, Meijer, G A, Baak, J P A & Meijer, C J L M 1999, ' Analysis by comparative genomic hybridization of epithelial and spindle cell components in sarcomatoid carcinoma and carcinosarcoma: histogenetic aspects ', Journal of Pathology, vol. 189, pp. 338-343 . https://doi.org/10.1002/(SICI)1096-9896(199911)189:3<338::AID-PATH429>3.0.CO;2-Q
Torenbeek, R, Hermsen, M A J A, Meijer, G A, Baak, J P A & Meijer, C J L M 1999, ' Analysis by comparative genomic hybridization of epithelial and spindle cell components in sarcomatoid carcinoma and carcinosarcoma: histogenetic aspects ', Journal of Pathology, vol. 189, pp. 338-343 . https://doi.org/10.1002/(SICI)1096-9896(199911)189:3<338::AID-PATH429>3.0.CO;2-Q
Sarcomatoid carcinomas and carcinosarcomas are histologically malignant biphasic neoplasms with an epithelial and a spindle cell component. Both a polyclonal and a monoclonal origin have been postulated for these tumours, but the latter has been favo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab1e3cdce29f7ffe3f847b1828fdb8e
https://doi.org/10.1002/(sici)1096-9896(199911)189:3<338::aid-path429>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199911)189:3<338::aid-path429>3.0.co
Autor:
Jan P. A. Baak, Gerrit A. Meijer, Jan W. W. Walboomers, Paul J. van Diest, Peter J.F. Snijders, Mario A. J. A. Hermsen, Janneke Weiss
Publikováno v:
The Journal of Pathology. 186:356-362
Within the subgroup of lymph node-negative breast cancers, there is a need for accurate prognostic indicators to select high-risk patients. Comparative genomic hybridization (CGH) provides an opportunity to screen the whole genome for chromosomal abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a02e2952e52fde33de49aee1e74e9f
https://doi.org/10.1002/(sici)1096-9896(199812)186:4<356::aid-path196>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199812)186:4<356::aid-path196>3.0.co
Autor:
Mario A J A Hermsen, Peter Demant, Jan Baak, Claudia A. L. Ruivenkamp, Cindy Postma, Gerrit A. Meijer, Anita M. Klous
Publikováno v:
Oncogene, 22(22), 3472-4. Nature Publishing Group
Ruivenkamp, C, Hermsen, M A J A, Postma, C, Klous, A, Baak, J, Meijer, G A & Demant, P 2003, ' LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21. ', Oncogene, vol. 22, no. 22, pp. 3472-4 . https://doi.org/10.1038/sj.onc.1206246
Ruivenkamp, C, Hermsen, M A J A, Postma, C, Klous, A, Baak, J, Meijer, G A & Demant, P 2003, ' LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21. ', Oncogene, vol. 22, no. 22, pp. 3472-4 . https://doi.org/10.1038/sj.onc.1206246
Recently, the gene PTPRJ (protein tyrosine phosphatase receptor type J) was identified as the candidate gene for the mouse colon cancer susceptibility locus Scc1. Its human homologue PTPRJ is frequently deleted in several cancer types, including colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cc1629ffd80b986568dfeb37a41186
https://doi.org/10.1038/sj.onc.1206246
https://doi.org/10.1038/sj.onc.1206246
Autor:
Erik Hooijberg, Mario A J A Hermsen, Esther W. M. Kueter, Antoinette A. T. P. Brink, Kirsten B.J. Scholten, Marianne Tijssen, Gerrit A. Meijer, Marco W.J. Schreurs, Chris J.L.M. Meijer, Bauke Ylstra, Ramon I. Klein Geltink
Publikováno v:
Schreurs, M W J, Hermsen, M A J A, Geltink, R I K, Scholten, K B J, Brink, A A T P, Kueter, E W M, Tijssen, M, Meijer, C J L M, Ylstra, B, Meijer, G A & Hooijberg, E 2005, ' Genomic stability and functional activity may be lost in telomerase-transduced human CD8 + T lymphocytes ', Blood, vol. 106, no. 8, pp. 2663-2670 . https://doi.org/10.1182/blood-2004-09-3742
Blood, 106(8), 2663-2670. American Society of Hematology
Blood, 106(8), 2663-2670. American Society of Hematology
To obtain the large amount of T cells required for adoptive immunotherapy in a clinical setting, T-cell lifespan extension by human telomerase reverse transcriptase (hTERT) transduction is of particular interest. However, constitutive expression of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7ef2a61428b450f33dbd78e8cdf737
https://research.vumc.nl/en/publications/278b5c38-ab5d-432e-a6bc-4152dc967105
https://research.vumc.nl/en/publications/278b5c38-ab5d-432e-a6bc-4152dc967105
Autor:
Mario A. J. A. Hermsen, Eliane Gluckman, Hans Joenje, Peter J.F. Snijders, Johan Wennerberg, Ruud H. Brakenhoff, C. René Leemans, Grover C. Bagby, Martin A. Rooimans, Jean Soulier, Hester J.T. van Zeeburg, Gerard Pals
Publikováno v:
van Zeeburg, H J, Snijders, P J F, Pals, G, Hermsen, M A, Rooimans, M A, Bagby, G, Soulier, J, Gluckman, E, Wennerberg, J, Leemans, C R, Joenje, H & Brakenhoff, R H 2005, ' Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients ', Cancer Research, vol. 65, no. 4, pp. 1271-1276 . https://doi.org/10.1158/0008-5472.CAN-04-3665
Cancer Research, 65(4), 1271-1276. American Association for Cancer Research Inc.
Cancer Research, 65(4), 1271-1276. American Association for Cancer Research Inc.
Patients with Fanconi anemia (FA) are prone to develop malignancies at an early age. Besides hematologic malignancies, squamous cell carcinomas in the anogenital region and head and neck are also frequently found in these patients. The aim of this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d723834bf786456671d6b2cdc0963906
https://pubmed.ncbi.nlm.nih.gov/15735012
https://pubmed.ncbi.nlm.nih.gov/15735012