Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Mario A. Flores-Valdez"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/bc23f21548844ff495b29b3c8b83ab01
Autor:
Mario A. Flores-Valdez, César Pedroza-Roldán, Michel de Jesús Aceves-Sánchez, Eliza J. R. Peterson, Nitin S. Baliga, Rogelio Hernández-Pando, JoLynn Troudt, Elizabeth Creissen, Linda Izzo, Helle Bielefeldt-Ohmann, Thomas Bickett, Angelo A. Izzo
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Mycobacterium tuberculosis (M. tuberculosis), the causative agent of human tuberculosis (TB), is estimated to be harbored by up to 2 billion people in a latent TB infection (LTBI) state. The only TB vaccine approved for use in humans, BCG, does not c
Externí odkaz:
https://doaj.org/article/3b14c2891c0b40eb8b5aff55e0e7a1ff
Autor:
Giuseppe D’Auria, Yordan Hodzhev, Michel de Jesús Aceves-Sánchez, Andrés Moya, Stefan Panaiotov, Mario Alberto Flores-Valdez
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Background: Bacillus Calmette–Guérin (BCG) remains the only vaccine to prevent tuberculosis (TB) during childhood, with relatively low to no efficacy against pulmonary TB in adolescents and adults. BCG consists of close to 15 different su
Externí odkaz:
https://doaj.org/article/fce788f56c2442c1bc4d95a0a8e473c9
Autor:
Kee Woong Kwon, Michel de Jesús Aceves-Sánchez, Cristian Alfredo Segura-Cerda, Eunsol Choi, Helle Bielefeldt-Ohmann, Sung Jae Shin, Mario Alberto Flores-Valdez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Previously, we reported that a hygromycin resistant version of the BCGΔBCG1419c vaccine candidate reduced tuberculosis (TB) disease in BALB/c, C57BL/6, and B6D2F1 mice infected with Mycobacterium tuberculosis (Mtb) H37Rv. Here, the second-g
Externí odkaz:
https://doaj.org/article/7166e761db4248398a4fcf3737c84427
Autor:
Aurora Dolores Arista-Regalado, Jeannette Barba-León, Victor Humberto Bustamante, Mario Alberto Flores-Valdez, Jorge Gaona, Maira Juliana Fajardo-Guerrero
Publikováno v:
Journal of Food Protection, Vol 86, Iss 5, Pp 100085- (2023)
Salmonella enterica is a foodborne pathogen that can be internalized into fresh produce. Most of the Salmonella virulence genes are clustered in regions denominated Salmonella Pathogenicity Islands (SPI). SPI-1 encodes a Type Three Secretion System (
Externí odkaz:
https://doaj.org/article/706de58acd5c49b9ba8c41c9c595e29b
Autor:
Manuja Gunasena, Rajni Kant Shukla, Naiquan Yao, Oscar Rosas Mejia, Michael D. Powell, Kenneth J. Oestreich, Michel de Jesús Aceves-Sánchez, Mario Alberto Flores-Valdez, Namal P. M. Liyanage, Richard T. Robinson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The vaccine Mycobacterium bovis Bacillus Calmette-Guérin (BCG) elicits an immune response that is protective against certain forms of tuberculosis (TB); however, because BCG efficacy is limited it is important to identify alternative TB vac
Externí odkaz:
https://doaj.org/article/39d7006d20634ee79c2e206a6e612978
Vaccination with BCGΔBCG1419c protects against pulmonary and extrapulmonary TB and is safer than BCG
Autor:
Michel de Jesús Aceves-Sánchez, Mario Alberto Flores-Valdez, César Pedroza-Roldán, Elizabeth Creissen, Linda Izzo, Fabiola Silva-Angulo, Clinton Dawson, Angelo Izzo, Helle Bielefeldt-Ohmann, Cristian Alfredo Segura-Cerda, Wendy López-Romero, Jorge Bravo-Madrigal, Jorge Alberto Barrios-Payán, Miguel Ángel de la Cruz, Miguel Ares, María Guadalupe Jorge-Espinoza
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract A single intradermal vaccination with an antibiotic-less version of BCGΔBCG1419c given to guinea pigs conferred a significant improvement in outcome following a low dose aerosol exposure to M. tuberculosis compared to that provided by a sin
Externí odkaz:
https://doaj.org/article/5c59aca1dc2a4630bd0accb20d8195d8
Autor:
Mario Alberto Flores-Valdez, Michel de Jesús Aceves-Sánchez, Eliza J. R. Peterson, Nitin Baliga, Jorge Bravo-Madrigal, Miguel Ángel De la Cruz-Villegas, Miguel A. Ares, Sarah Born, Martin Voskuil, Nayeli Areli Pérez-Padilla, Mirna Burciaga-Flores, Tanya Amanda Camacho-Villegas, María Guadalupe Espinoza-Jorge
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Mycobacterium tuberculosis and M. smegmatis form drug-tolerant biofilms through dedicated genetic programs. In support of a stepwise process regulating biofilm production in mycobacteria, it was shown elsewhere that lsr2 participates in inte
Externí odkaz:
https://doaj.org/article/2c128ef7180346aa9fd5d3b4273f0b57
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2749 (2022)
Vaccination is an excellent approach to stimulating the host immune response and reducing human morbidity and mortality against microbial infections, such as tuberculosis (TB). Bacillus Calmette–Guerin (BCG) is the most widely administered vaccine
Externí odkaz:
https://doaj.org/article/fec9cbc3aa1d400fb754930594ab9bc3
Autor:
Mario Alberto Flores-Valdez, Gabriele A. Fontana, Julia K. Reinert, Nicolas H. Thomä, Ulrich Rass
Publikováno v:
Microbial Cell, Vol 5, Iss 7, Pp 327-343 (2018)
Cells have evolved conserved mechanisms to protect DNA ends, such as those at the termini of linear chromosomes, or those at DNA double-strand breaks (DSBs). In eukaryotes, DNA ends at chromosomal termini are packaged into proteinaceous structures ca
Externí odkaz:
https://doaj.org/article/e0ae7b362ed848aa84340d643a0783f4