Výsledky vyhledávání - "Mario Caputi"

Akademický článek

Molecular basis and clinical management of Pompe disease

Autor: Giancarlo Parenti, Giuseppe Di Iorio, Simone Sampaolo, Giuseppe Fiorentino, Vincenzo Farina, Simona Fecarotta, Fabio Valente, Serena Ascione, Mario Caputi, Generoso Andria

Publikováno v: Cardiogenetics, Vol 3, Iss 1S, Pp e5-e5 (2013)

Pompe disease (glycogenosis type II) is a rare autosomal recessive lysosomal storage disorder due to mutations of the GAA gene, leading to the deficiency of acid α-glucosidase and consequent glycogen storage in various tissues, mainly in the skeleta

Externí odkaz: https://doaj.org/article/fd641ed5d0d84b90aff8023d526e046c

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Modulation of Cellular Migration and Survival by c-Myc through the Downregulation of Urokinase (uPA) and uPA Receptor

Autor: Julian Downward, Almut Schulze, Ingram Iaccarino, Giuseppina Votta, Maria Patrizia Stoppelli, Mario Caputi, Daniela Alfano

Publikováno v: Molecular and cellular biology
30 (2010): 1838–1851. doi:10.1128/MCB.01442-09
info:cnr-pdr/source/autori:Alfano D.; Votta G.; Schulze A.; Downward J.; Caputi M.; Stoppelli M.P.; Iaccarino I./titolo:Modulation of cellular migration and survival by c-Myc through the downregulation of urokinase (uPA) and uPA receptor/doi:10.1128%2FMCB.01442-09/rivista:Molecular and cellular biology (Print)/anno:2010/pagina_da:1838/pagina_a:1851/intervallo_pagine:1838–1851/volume:30

It has been proposed that c-Myc proapoptotic activity accounts for most of its restraint of tumor formation. We established a telomerase-immortalized human epithelial cell line expressing an activatable c-Myc protein. We found that c-Myc activation i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd84d8da8a9ae202a747fb8b11787e27
https://doi.org/10.1128/mcb.01442-09

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Biological targets for therapeutic interventions in COPD: clinical potential

Autor: Luca Gallelli, Serafino A. Marsico, Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli, Teresa Renda, Mario Caputi

Publikováno v: International Journal of Chronic Obstructive Pulmonary Disease

COPD is a widespread inflammatory respiratory disorder characterized by a progressive, poorly reversible airflow limitation. Currently available therapies are mostly based on those used to treat asthma. However, such compounds are not able to effecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f5500b661533ee88dd5f41af770917
https://doi.org/10.2147/copd.2006.1.3.321

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Autor: A M Groeger, Mario Caputi, Antonio Mancini, V Esposito, Bruno Vincenzi, A. De Luca, Giuseppe Tonini, Alfonso Baldi, Paolo Persichetti, Gennaro Citro, Feliciano Baldi, Daniele Santini

Publikováno v: Journal of Clinical Pathology. 58:734-739

Background: Experimental evidence suggests that lung cancer development and progression can be linked to an increased proliferation rate. Aims/Methods: To evaluate the immunohistochemical expression of seven components of the cell cycle machinery in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50b2e00db185e11ada35552b28c87df
https://doi.org/10.1136/jcp.2004.023531

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Effects of hydrogen peroxide on MAPK activation, IL-8 production and cell viability in primary cultures of human bronchial epithelial cells

Autor: Luca Gallelli, Francesco Costanzo, Mario Caputi, Francesco Rossi, Serafino A. Marsico, Alessandro Vatrella, Giovanni Cuda, Bruno D'Agostino, V. Gioffrè, D. Fratto, Rosario Maselli, Girolamo Pelaia

Publikováno v: Journal of Cellular Biochemistry. 93:142-152

The airway epithelium is continuously exposed to inhaled oxidants, including airborne pollutants and cigarette smoke, which can exert harmful proinflammatory and cytotoxic effects. Therefore, the aim of our study was to investigate, in primary cultur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::780317f3d29ed7bb580f208f2f83c775
https://doi.org/10.1002/jcb.20124

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Urokinase-type plasminogen activator up-regulates the expression of its cellular receptor through a post-transcriptional mechanism

Autor: Nunzia Montuori, Mariano Santoli, Mario Caputi, Pia Ragno, Paola Taglialatela, Alessandro Mancini, Guido Rossi, Amalia Mattiello

Publikováno v: FEBS letters
508 (2001): 379–384.
info:cnr-pdr/source/autori:Montuori N. 1, Mattiello A. 2, Mancini A. 2, Santoli M. 3, Taglialatela P. 3, Caputi M. 2, Rossi G. 1-3, Ragno P. 1/titolo:Urokinase-type plasminogen activator up-regulates the expression of its cellular receptor through a post-transcriptional mechanism./doi:/rivista:FEBS letters (Print)/anno:2001/pagina_da:379/pagina_a:384/intervallo_pagine:379–384/volume:508

We have recently reported that the urokinase-type plasminogen activator (uPA) up-regulates the cell surface expression of its own receptor (uPAR) in several cell types, independently of its enzymatic activity. uPA has no effect on kidney 293 cells wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4df941bbf4ae6f2fe3389472cf90dd
https://doi.org/10.1016/s0014-5793(01)03104-0

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Autor: Feliciano Baldi, Mario Caputi, Yan Fu, Pier Paolo Claudio, M. Michele Pisano, Antonio De Luca, V. Esposito, Alfonso Baldi, Antonio Giordano

Publikováno v: Journal of Cellular Physiology. 172:265-273

Mammalian cell cycle progression is regulated by sequential activation and inactivation of cyclin-dependent kinases (cdks). Recently, several new members of the cdk family were cloned, and some of these were shown to complex with different cyclins an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2228eb4a561a333ed6df8f041519d4af
https://doi.org/10.1002/(sici)1097-4652(199708)172:2<265::aid-jcp13>3.0.co

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Preliminary study on the correlation between grading and histology of solitary pulmonary nodules and contrast enhancement and [18F]fluorodeoxyglucose standardised uptake value after evaluation by dynamic multiphase CT and PET/CT

Publikováno v: Journal of Clinical Pathology

Aim To evaluate whether the histology and grading of solitary pulmonary nodules (SPNs) correlated with the results of dynamic multiphase multidetector CT (MDCT) and the [ 18 F]fluorodeoxyglucose standardised uptake value (SUV) in 30 patients. Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da52a221f251332eb17dc8e8939110f6
http://hdl.handle.net/11591/322180

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Adenosine Receptor Ligands in Clinical Trials

Autor: R. La Montagna, G. Russo, Flavio Rizzolio, Antonio Giordano, Mario Caputi, Tiziano Tuccinardi

Publikováno v: ResearcherID

Adenosine and its receptors play different roles in normal and patho-physiological conditions. For these reasons, many laboratories have focused their attention on dissecting the molecular pathway underlying the mechanism of action of this nucleoside

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5591e7d9aacfc16779704336a3c3d637
http://hdl.handle.net/11568/142663

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