Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Mario, Turriziani"'
1
Carcinoembryonic Antigen (CEA)-Based Cancer Vaccines: Recent Patents and Antitumor Effects from Experimental Models to Clinical Trials
Autor: Mario Turriziani, Valerio Izzi, Laura Masuelli, Monica Benvenuto, Massimo Fantini, Pamela Sacchetti, Roberto Bei, Andrea Modesti
Publikováno v: ResearcherID
Carcinoembryonic antigen (CEA), a glycosylated protein of MW 180 kDa, is overexpressed in a wide range of human carcinomas, including colorectal, gastric, pancreatic, non-small cell lung and breast carcinomas. Accordingly, CEA is one of several oncof
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a393ad26e0ed77a2da700c3b7ff0a04
https://doi.org/10.2174/157489212801820020
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2
The Use of Temozolomide for the Treatment of Malignant Tumors: Clinical Evidence and Molecular Mechanisms of Action
Autor: Roberto Bei, Laura Marzocchella, Mario Turriziani
Publikováno v: Recent Patents on Anti-Cancer Drug Discovery. 5:172-187
Temozolomide (TMZ) is a monofunctional methylating agent which is spontaneously activated in aqueous solution into the dacarbazine metabolite 5-(3-methyl-1-triazeno)imidazole-4-carboxamide. This drug has been approved for the treatment of metastatic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6044f214c1b2e52ed3a8e8b335aa3d93
https://doi.org/10.2174/157489210791760526
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3
Topical Use of Sucralfate in Epithelial Wound Healing: Clinical Evidence and Molecular Mechanisms of Action
Autor: Roberto Bei, Andrea Modesti, Giovanni Tumino, Laura Masuelli, Mario Turriziani
Publikováno v: Recent Patents on Inflammation & Allergy Drug Discovery. 4:25-36
Sucralfate is a basic aluminium salt of sucrose octasulphate which was orally employed for prevention and treatment of several gastrointestinal diseases including gastroesophageal reflux, gastric and duodenal ulcer. Recent studies have employed sucra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3414f8d532d3d64bea9b781a33908ec9
https://doi.org/10.2174/187221310789895649
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4
Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus
Autor: Carmine Cardillo, Julio A. Panza, Davide Lauro, Angelo Scuteri, Roberto Leo, Micaela Iantorno, Massimo Federici, Michael J. Quon, Umberto Campia, Giulio Cesare Cocciolillo, Mario Turriziani, A. Fusco, Renato Lauro, Manfredi Tesauro, Stefano Rizza
Publikováno v: Metabolism. 56:413-419
Endothelial dysfunction, insulin resistance, and elevated levels of circulating proinflammatory markers are among the earliest detectable abnormalities in people at risk for atherosclerosis. Accelerated atherosclerosis is a leading contributor to mor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e828f784e083a682579502e28439b59b
https://doi.org/10.1016/j.metabol.2006.10.026
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5
Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemic cells
Autor: Mario Turriziani, L Levati, Lucio Tentori, Barry Gold, R. Madaio, Patrizia Vernole, Grazia Graziani, Dande P, P Lacal, Enzo Bonmassar, Ilaria Portarena, Alessandra Balduzzi
Publikováno v: Scopus-Elsevier
Leukemia 14 (2000): 1451–1459.
info:cnr-pdr/source/autori:Tentori L., Vernole P., Lacal P.M., Madaio R., Portarena I., Levati L., Balduzzi A.,Turriziani M., Dande P., Gold B., Bonmassar E., Graziani G./titolo:Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemia cells./doi:/rivista:Leukemia/anno:2000/pagina_da:1451/pagina_a:1459/intervallo_pagine:1451–1459/volume:14
Mismatch repair deficiency contributes to tumor cell resistance to O6-guanine methylating compounds and to other antineoplastic agents. Here we demonstrate that MeOSO2(CH2)2- lexitropsin (Me-Lex), a DNA minor groove alkylating compound which generate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8480fc9b726478d6293721b8bc3a137f
https://doi.org/10.1038/sj.leu.2401842
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6
Development of a NovelIn VitroChemosensitivity Assay: Telomerase as a Possible Marker of Tumor Cell Survival
Autor: Isabella Faraoni, Mario Turriziani, E. Bonmasssar, Grazia Graziani, L De Vecchis
Publikováno v: Journal of Chemotherapy. 8:394-398
Telomerase is a ribonucleoprotein enzyme which is involved in the maintenance of chromosome ends. Telomerase activity (TLMA) is required for cell immortality and can be considered a ubiquitous tumor marker. In this study we describe a new approach fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afe242d9da544dc05d78df3ddc00355
https://doi.org/10.1179/joc.1996.8.5.394
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7
Helicobacter pylori infection associates with a mucosal downregulation of Ghrelin, negative regulator of Th1-cell responses
Autor: Ivan Monteleone, Giovanni Monteleone, Roberta Caruso, Flavio Caprioli, Francesco Pallone, Omero Alessandro Paoluzi, Manfredi Tesauro, Mario Turriziani, Giovanna Del Vecchio Blanco
Background Helicobacter pylori (Hp)-related gastritis is characterized by a predominant T helper (Th)1/Th17 cell immunity. Ghrelin (GR) has immunoregulatory properties and inhibits experimental Th cell-dependent pathology. Aims To evaluate whether Hp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234e69450bea9981f53c2505896d825c
http://hdl.handle.net/2108/121240
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