Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Mario, Schelhaas"'
Autor:
Yuzhen Feng, Dominik van Bodegraven, Alan Kádek, Ignacio L. B. Munguira, Laura Soria-Martinez, Sarah Nentwich, Sreedeepa Saha, Florian Chardon, Daniel Kavan, Charlotte Uetrecht, Mario Schelhaas, Wouter H. Roos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract High-risk human papillomaviruses (HPVs) cause various cancers. While type-specific prophylactic vaccines are available, additional anti-viral strategies are highly desirable. Initial HPV cell entry involves receptor-switching induced by stru
Externí odkaz:
https://doaj.org/article/ad05749e2602467997b382ccd9878f0a
Autor:
Matteo Rizzato, Fuxiang Mao, Florian Chardon, Kun-Yi Lai, Ruth Villalonga-Planells, Hannes C. A. Drexler, Marion E. Pesenti, Mert Fiskin, Nora Roos, Kelly M. King, Shuaizhi Li, Eduardo R. Gamez, Lilo Greune, Petra Dersch, Claudia Simon, Murielle Masson, Koenraad Van Doorslaer, Samuel K. Campos, Mario Schelhaas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Human papillomavirus (HPV) coopts mitosis for nuclear entry by tethering the viral DNA to mitotic chromosomes, a process facilitated by the viral minor capsid protein L2. Here, Rizzato et al. show that L2 contains conserved phosphorylation motifs wit
Externí odkaz:
https://doaj.org/article/b57b1e1f90134a7ead1de9a3cb32c825
Autor:
Kun-Yi Lai, Matteo Rizzato, Inci Aydin, Ruth Villalonga-Planells, Hannes C A Drexler, Mario Schelhaas
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009580 (2021)
Human papillomaviruses (HPVs) utilize an atypical mode of nuclear import during cell entry. Residing in the Golgi apparatus until mitosis onset, a subviral complex composed of the minor capsid protein L2 and viral DNA (L2/vDNA) is imported into the n
Externí odkaz:
https://doaj.org/article/b696005e15964b3dbafb159d5e98b4a8
Autor:
Matteo Bosso, Caterina Prelli Bozzo, Dominik Hotter, Meta Volcic, Christina M Stürzel, Annika Rammelt, Yi Ni, Stephan Urban, Miriam Becker, Mario Schelhaas, Sabine Wittmann, Maria H Christensen, Florian I Schmidt, Thomas Gramberg, Konstantin M J Sparrer, Daniel Sauter, Frank Kirchhoff
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008752 (2020)
Members of the family of pyrin and HIN domain containing (PYHIN) proteins play an emerging role in innate immunity. While absent in melanoma 2 (AIM2) acts a cytosolic sensor of non-self DNA and plays a key role in inflammasome assembly, the γ-interf
Externí odkaz:
https://doaj.org/article/d0e102ecfa314249b001ab0c86014b21
Autor:
Stefan Schulte-Merker, Ulrich Dobrindt, Andreas van Impel, Thomas Zobel, Katharina Uphoff, Mario Schelhaas, Michael F. Berger, Yvonne Huisman, Jeroen Bussmann
Publikováno v:
GLIA, 70(1), 35-49. WILEY
Glia, 70(1), 35-49. WILEY
Glia, 70(1), 35-49. WILEY
Brain lymphatic endothelial cells (BLECs) constitute a group of loosely connected endothelial cells that reside within the meningeal layer of the zebrafish brain without forming a vascular tubular system. BLECs have been shown to readily endocytose e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873d00f9a5d7a503a281e19ef130cccd
https://doi.org/10.1002/glia.24081
https://doi.org/10.1002/glia.24081
Autor:
Inci Aydin, Ruth Villalonga-Planells, Lilo Greune, Matthew P Bronnimann, Christine M Calton, Miriam Becker, Kun-Yi Lai, Samuel K Campos, M Alexander Schmidt, Mario Schelhaas
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006308 (2017)
Incoming papillomaviruses (PVs) depend on mitotic nuclear envelope breakdown to gain initial access to the nucleus for viral transcription and replication. In our previous work, we hypothesized that the minor capsid protein L2 of PVs tethers the inco
Externí odkaz:
https://doaj.org/article/0b0af9093bfb42c7950c6f3576d65254
Autor:
Freya Molenberghs, Marlies Verschuuren, Lauran Vandeweyer, Sarah Peeters, Johannes Bogers, Claudina Perez Novo, Wim Vanden Berghe, Hans De Reu, Nathalie Cools, Mario Schelhaas, Winnok De Vos
Human papillomavirus (HPV) infection is the prime elicitor of cervical and head-and-neck cancers. The HPV genome enters the nucleus during mitosis when the nuclear envelope dismantles. Since lamins safeguard nuclear integrity during interphase, we as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d82bf125114078a010c9782299783ef1
https://doi.org/10.21203/rs.3.rs-1911728/v1
https://doi.org/10.21203/rs.3.rs-1911728/v1
Autor:
Freya Molenberghs, Marlies Verschuuren, Michaël Barbier, Johannes J. Bogers, Nathalie Cools, Peter Delputte, Mario Schelhaas, Winnok H. De Vos
Publikováno v:
Cytometry
Cytometry: part A
Cytometry: part A
Human papillomaviruses (HPV) are small, non-enveloped DNA viruses, which upon chronic infection can provoke cervical and head-and-neck cancers. Although the infectious life cycle of HPV has been studied and a vaccine is available for the most prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f84e3818774f3fb50c2515a3ab40d7
https://pubmed.ncbi.nlm.nih.gov/35668549
https://pubmed.ncbi.nlm.nih.gov/35668549
Autor:
Berend Snijder, Raphael Sacher, Pauli Rämö, Prisca Liberali, Karin Mench, Nina Wolfrum, Laura Burleigh, Cameron C Scott, Monique H Verheije, Jason Mercer, Stefan Moese, Thomas Heger, Kristina Theusner, Andreas Jurgeit, David Lamparter, Giuseppe Balistreri, Mario Schelhaas, Cornelis A M De Haan, Varpu Marjomäki, Timo Hyypiä, Peter J M Rottier, Beate Sodeik, Mark Marsh, Jean Gruenberg, Ali Amara, Urs Greber, Ari Helenius, Lucas Pelkmans
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-18 (2012)
Abstract Isogenic cells in culture show strong variability, which arises from dynamic adaptations to the microenvironment of individual cells. Here we study the influence of the cell population context, which determines a single cell's microenvironme
Externí odkaz:
https://doaj.org/article/099ab570f30a48879d45bf21e977d966
Publikováno v:
Viruses, Vol 10, Iss 11, p 636 (2018)
Glycans are, with nucleic acids, proteins and lipids, one of the four founding structures of cellular life. Due to their non-template synthesis, they are inherently heterogeneous and difficult to study with regards to their structure and function. Si
Externí odkaz:
https://doaj.org/article/e7075d9fc10543d8aef78a367d8b59f7