Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Mario, Mikula"'
Autor:
Hans Peter Weitzenböck, Anna Gschwendtner, Christoph Wiesner, Maren Depke, Frank Schmidt, Franz Trautinger, Markus Hengstschläger, Harald Hundsberger, Mario Mikula
Publikováno v:
Cancer Medicine, Vol 11, Iss 4, Pp 956-967 (2022)
Abstract Malignant melanoma is the deadliest form of skin cancer and NRF2 has been proposed as a main regulator of tumor cell malignancy. Still the mechanisms how NRF2 is contributing to melanoma progression are incompletely understood. Here we analy
Externí odkaz:
https://doaj.org/article/6c203d2ccf1f419a834d63c2f9f2095f
Autor:
Laurenz Vock, Anna Gschwendtner, Oliver Eckel, Madalina A. Mirea, Markus Hengstschläger, Mario Mikula
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/50e142e6dd4149b18c6eaf62777729fc
Autor:
Sigrid Vondra, Victoria Kunihs, Tana Eberhart, Karin Eigner, Raimund Bauer, Peter Haslinger, Sandra Haider, Karin Windsperger, Günter Klambauer, Birgit Schütz, Mario Mikula, Xiaowei Zhu, Alexander E. Urban, Roberta L. Hannibal, Julie Baker, Martin Knöfler, Herbert Stangl, Jürgen Pollheimer, Clemens Röhrl
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 11, Pp 1922-1934 (2019)
During pregnancy, extravillous trophoblasts (EVTs) invade the maternal decidua and remodel the local vasculature to establish blood supply for the growing fetus. Compromised EVT function has been linked to aberrant pregnancy associated with maternal
Externí odkaz:
https://doaj.org/article/f74acbe79c894b78b6402448b83db2fa
Autor:
Markus Axmann, Birgit Plochberger, Mario Mikula, Florian Weber, Witta Monika Strobl, Herbert Stangl
Publikováno v:
Membranes, Vol 11, Iss 11, p 882 (2021)
Cholesterol is one of the main constituents of plasma membranes; thus, its supply is of utmost importance. This review covers the known mechanisms of cholesterol transfer from circulating lipoprotein particles to the plasma membrane, and vice versa.
Externí odkaz:
https://doaj.org/article/db336cda79b445d08cc3975682c81671
Autor:
Philipp Velicky, Gudrun Meinhardt, Kerstin Plessl, Sigrid Vondra, Tamara Weiss, Peter Haslinger, Thomas Lendl, Karin Aumayr, Mario Mairhofer, Xiaowei Zhu, Birgit Schütz, Roberta L Hannibal, Robert Lindau, Beatrix Weil, Jan Ernerudh, Jürgen Neesen, Gerda Egger, Mario Mikula, Clemens Röhrl, Alexander E Urban, Julie Baker, Martin Knöfler, Jürgen Pollheimer
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007698 (2018)
Genome amplification and cellular senescence are commonly associated with pathological processes. While physiological roles for polyploidization and senescence have been described in mouse development, controversy exists over their significance in hu
Externí odkaz:
https://doaj.org/article/6f5412da4e4048ac916cec88d7097328
Autor:
Irina Mirkina, Emir Hadzijusufovic, Clemens Krepler, Mario Mikula, Diana Mechtcheriakova, Sabine Strommer, Alexander Stella, Erika Jensen-Jarolim, Christoph Höller, Volker Wacheck, Hubert Pehamberger, Peter Valent
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84417 (2014)
Malignant melanoma is a life-threatening skin cancer increasingly diagnosed in the western world. In advanced disease the prognosis is grave. Growth and metastasis formation in melanomas are regulated by a network of cytokines, cytokine-receptors, an
Externí odkaz:
https://doaj.org/article/cc58a81c66b84d88bfd1fe50d071f9fa
Autor:
Andrea Preitschopf, Kongzhao Li, David Schörghofer, Katharina Kinslechner, Birgit Schütz, Ha Thi Thanh Pham, Margit Rosner, Gabor Jozsef Joo, Clemens Röhrl, Thomas Weichhart, Herbert Stangl, Gert Lubec, Markus Hengstschläger, Mario Mikula
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107004 (2014)
Schwann cell development is hallmarked by the induction of a lipogenic profile. Here we used amniotic fluid stem (AFS) cells and focused on the mechanisms occurring during early steps of differentiation along the Schwann cell lineage. Therefore, we i
Externí odkaz:
https://doaj.org/article/7120d6f501a9447891533f32de9215d5
Autor:
Nyamdelger Sukhbaatar, Daniela Unterleuthner, Markus Hengstschläger, Michael Bergmann, Michaela Lang, Andreas Bergthaler, Karl Katholnig, Thomas Weichhart, Mark A. Magnuson, Birgit Schütz, Julia M. Matschinger, Merima Herac, Helmut Dolznig, David Schörghofer, Gernot Schabbauer, Stephanie D. Fritsch, Mario Mikula, Monika Linke, Andreas Spittler, Martin Hirtl
The mechanistic target of rapamycin complex 2 (mTORC2) is a potentially novel and promising anticancer target due to its critical roles in proliferation, apoptosis, and metabolic reprogramming of cancer cells. However, the activity and function of mT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfff9be1d35172b4f01bdd6a30120c8c
https://europepmc.org/articles/PMC6824305/
https://europepmc.org/articles/PMC6824305/
Autor:
Alexander Swoboda, Katharina Kinslechner, Fritz Aberger, Maria Vallianou, Christina Sternberg, Mario Mikula, Stefan Kubicek, David Schoerghofer, Robert Soukup, Ha Pham, Thomas Krausgruber, Jaqueline Horvath, Peter Petzelbauer, Friedrich Beermann, Christoph Bock, Markus Hengstschlaeger, Valeria Poli, André F. Rendeiro, Dagmar Stoiber, Boris Kovacic, Bettina Wingelhofer, Takashi Yokota, Lukas Kenner, Lionel Larue, Rainer Zenz, Richard Moriggl
Metastatic melanoma is hallmarked by its ability to switch oncogenic MITF expression. Here we tested the impact of STAT3 on melanoma onset and progression in association with MITF expression levels. We established a mouse melanoma model for deleting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d2aefaeae50be162a2e3e4f176c750
https://doi.org/10.1101/422832
https://doi.org/10.1101/422832
Autor:
Ha T. T. Pham, Zahra Kazemi, Maximilian Kauer, Jan Pencik, Barbara Sax, Barbara Maurer, Heinrich Kovar, Aykut Üren, Helmut Dolznig, Maximillian Hofbauer, Guenther H. S. Richter, Michaela Schlederer, Rahil Noorizadeh, Tahereh Javaheri, Lukas Kenner, Mario Mikula, Dave N. T. Aryee, EleniM. Tomazou, Harini Nivarthi, Christine Hartmann, Richard Moriggl, Jan Tuckermann, Florian Grebien, Malcolm Logan, Marc Wiedner
Publikováno v:
Cell Death & Disease
Since publication of the article, the authors became aware that Figure 6(A,D) contained errors in the bands and loading controls. The newly compiled Figure 6A and 6D is given below.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fae4950f9a2b37b6ea9fb7ab7ded23f
https://doi.org/10.1038/s41419-018-0773-9
https://doi.org/10.1038/s41419-018-0773-9