The in Vitro and in Vivo Anti-Cancer Potential of Mycobacterium Cell Wall Fraction (MCWF) Against Canine Transitional Cell Carcinoma of the Urinary Bladder

Autor: Aleksandar Masic, Chad M Johannes, C Mario Filion, Lucas Rodrigues

Publikováno v: Acta Veterinaria, Vol 67, Iss 4, Pp 477-494 (2017)
Acta veterinaria
Acta veterinaria, Faculty of Veterinary Medicine Belgrade, 2017, 67, 4, pp.477-494. ⟨10.1515/acve-2017-0039⟩

Transitional cell carcinoma (TCC), is the most common form of urinary bladder cancer in dogs and represents 2% of all reported canine cancers. Canine TCC is usually a high-grade invasive cancer and problems associated with TCC include urinary tract o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfdb618490af5e47999918c7d851cec
https://doaj.org/article/1542eef0e951427e9c34b7a006dc32f0

Mechanism and Function of Monoclonal Antibodies Targeting Siglec-15 for Therapeutic Inhibition of Osteoclastic Bone Resorption

Autor: Aida Kalbakji, Annie Fortin, Gilles Tremblay, Matthew Stuible, Mario Filion, Anna N. Moraitis, Stefan Saragosa

Publikováno v: Journal of Biological Chemistry. 289:6498-6512

The use of monoclonal antibodies to target functionally important cell-surface proteins on bone-resorbing osteoclasts represents a promising approach for treatment of cancer-associated bone loss and other skeletal pathologies. Previously, we identifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb79d3ddb5e62f1e84cbad27b541397
https://doi.org/10.1074/jbc.m113.494542

Direct Human Papillomavirus (HPV) Sequencing Method Yields a Novel HPV in a Human Immunodeficiency Virus–Positive Quebec Woman and Distinguishes a New HPV Clade

Autor: Juan Carlos Feoli-Fonseca, Luc L. Oligny, Pierre Russo, Pierre Brochu, Mario Filion, Wagner V. Yotov

Publikováno v: The Journal of Infectious Diseases. 178:1492-1496

Papillomaviruses of supergroup A exhibit genital tropism and are best known as etiologic agents for benign and malignant cervical lesions in women. A polymerase chain reaction direct sequencing approach with P-33-labeled dideoxynucleotides was used t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1465943eb53743f1e8c4a1da27d687cb
https://doi.org/10.1086/314461

Autoreactive T cells in healthy individuals show tolerancein vitro with characteristics similar to but distinct from clonal anergy

Autor: Amanda J. Bradley, Pierre Chartrand, Mario Filion, Francine Décary, Dana V. Devine

Publikováno v: European Journal of Immunology. 25:3123-3127

Peripheral tolerance to self antigens has been suspected to play an important role in the regulation of the immune response in humans since autoreactive T cells can be isolated from the peripheral blood of healthy individuals. The mechanism of this t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83f594a6f91e52462c165b007796437
https://doi.org/10.1002/eji.1830251120

Analysis of immunoglobulin class, IgG subclass and titre of HPA-1a antibodies in alloimmunized mothers giving birth to babies with or without neonatal alloimmune thrombocytopenia

Autor: Pierre Chartrand, Mindy Goldman, Chantal Proulx, Francine Décary, Dana V. Devine, Mario Filion, Amanda Bradley

Publikováno v: British Journal of Haematology. 87:813-817

Summary We analysed the titre and isotype composition of antibodies produced by mothers giving birth to babies with or without neonatal alloimmune thrombocytopenic purpura (NAITP) and patients with post-transfusion purpura (PTP). All these individual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffb352038f5ebce0d47aaa1c9a9907d
https://doi.org/10.1111/j.1365-2141.1994.tb06742.x