Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Mario, Dicato"'
Autor:
Barbora Orlikova-Boyer, Anne Lorant, Sruthi Reddy Gajulapalli, Claudia Cerella, Michael Schnekenburger, Jin-Young Lee, Ji Yeon Paik, Yejin Lee, David Siegel, David Ross, Byung Woo Han, Thi Kim Yen Nguyen, Christo Christov, Hyoung Jin Kang, Mario Dicato, Marc Diederich
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Background Despite advancements in chronic myeloid leukemia (CML) therapy with tyrosine kinase inhibitors (TKIs), resistance and intolerance remain significant challenges. Leukemia stem cells (LSCs) and TKI-resistant cells rely on altered mi
Externí odkaz:
https://doaj.org/article/5bd22e469361471b8bf8490d4dd2847c
Enhancing personalized immune checkpoint therapy by immune archetyping and pharmacological targeting
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106914- (2023)
Immune checkpoint inhibitors (ICIs) are an expanding class of immunotherapeutic agents with the potential to cure cancer. Despite the outstanding clinical response in patient subsets, most individuals become refractory or develop resistance. Patient
Externí odkaz:
https://doaj.org/article/87d335e3cc854e179639aab1f5554309
Autor:
Jaemyun Kim, Seungwon Ji, Jin-Young Lee, Jean Lorquin, Barbora Orlikova-Boyer, Claudia Cerella, Aloran Mazumder, Florian Muller, Mario Dicato, Olivier Detournay, Marc Diederich
Publikováno v:
Marine Drugs, Vol 21, Iss 4, p 233 (2023)
Palytoxin is considered one of the most potent biotoxins. As palytoxin-induced cancer cell death mechanisms remain to be elucidated, we investigated this effect on various leukemia and solid tumor cell lines at low picomolar concentrations. As palyto
Externí odkaz:
https://doaj.org/article/dc0f952db529426c888e603cf53e66b2
Autor:
Sébastien Chateauvieux, Anthoula Gaigneaux, Déborah Gérard, Marion Orsini, Franck Morceau, Barbora Orlikova-Boyer, Thomas Farge, Christian Récher, Jean-Emmanuel Sarry, Mario Dicato, Marc Diederich
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
Externí odkaz:
https://doaj.org/article/a19bb1a8bca94fabb787af7347cf2eaf
Autor:
Hamidou Têeda Ganamé, Yssouf Karanga, Issa Tapsoba, Mario Dicato, Marc F. Diederich, Claudia Cerella, Richard Wamtinga Sawadogo
Publikováno v:
Plants, Vol 10, Iss 7, p 1353 (2021)
Acacia macrostachya is used in Burkina Faso folk medicine for the treatment of inflammation and cancer. The purpose of this study was to evaluate the antioxidant and cytotoxic effects of this plant. The cytotoxic effects of root (dichloromethane B1 a
Externí odkaz:
https://doaj.org/article/6d4100fd6f3543308363ef3b1b540b44
Autor:
Sungmi Song, Sua Kim, Eslam R. El-Sawy, Claudia Cerella, Barbora Orlikova-Boyer, Gilbert Kirsch, Christo Christov, Mario Dicato, Marc Diederich
Publikováno v:
Marine Drugs, Vol 19, Iss 6, p 285 (2021)
Aplysinopsins are a class of marine indole alkaloids that exhibit a wide range of biological activities. Although both the indole and N-benzyl moieties of aplysinopsins are known to possess antiproliferative activity against cancer cells, their mecha
Externí odkaz:
https://doaj.org/article/57817b0540814cc78e3934b3af71d55f
Publikováno v:
Seminars in Cancer Biology. 80:58-72
The recent advances in cancer immunotherapy confirm the crucial role of the immune system in cancer progression and treatment. Chronic inflammation and reduced immune surveillance are both features of the tumor microenvironment. Strategies aimed at r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94877d8e45f97159a16b51f8ba312091
https://doi.org/10.1016/j.semcancer.2020.02.008
https://doi.org/10.1016/j.semcancer.2020.02.008
Autor:
Naira F. Z. Schneider, Claudia Cerella, Jin-Young Lee, Aloran Mazumder, Kyung Rok Kim, Annelise de Carvalho, Jennifer Munkert, Rodrigo M. Pádua, Wolfgang Kreis, Kyu-Won Kim, Christo Christov, Mario Dicato, Hyun-Jung Kim, Byung Woo Han, Fernão C. Braga, Cláudia M. O. Simões, Marc Diederich
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cardiac glycosides (CGs) are natural compounds used traditionally to treat congestive heart diseases. Recent investigations repositioned CGs as potential anticancer agents. To discover novel cytotoxic CG scaffolds, we selected the cardenolide glucoev
Externí odkaz:
https://doaj.org/article/1962657514af42deb6f0eab6afdc2661
Autor:
Wamtinga Richard Sawadogo, Rainatou Boly, Claudia Cerella, Marie Hélène Teiten, Mario Dicato, Marc Diederich
Publikováno v:
Molecules, Vol 20, Iss 4, Pp 7097-7142 (2015)
Although considerable effort and progress has been made in the search for new anticancer drugs and treatments in the last several decades, cancer remains a major public health problem and one of the major causes of death worldwide. Many sources, incl
Externí odkaz:
https://doaj.org/article/3be0704544ec4789a6e79d47ba46540e
Publikováno v:
Molecules, Vol 19, Iss 12, Pp 20839-20863 (2014)
Cancer is a multifactorial disease that requires treatments able to target multiple intracellular components and signaling pathways. The natural compound, curcumin, was already described as a promising anticancer agent due to its multipotent properti
Externí odkaz:
https://doaj.org/article/06eab1fa3af645a39a9cbb37851f3117