Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Mario, Chiariello"'
Autor:
Lorenzo Franci, Giulia Vallini, Franca Maria Bertolino, Vittoria Cicaloni, Giovanni Inzalaco, Mattia Cicogni, Laura Tinti, Laura Calabrese, Virginia Barone, Laura Salvini, Pietro Rubegni, Federico Galvagni, Mario Chiariello
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103131- (2024)
Oxidation processes in mitochondria and different environmental insults contribute to unwarranted accumulation of reactive oxygen species (ROS). These, in turn, rapidly damage intracellular lipids, proteins, and DNA, ultimately causing aging and seve
Externí odkaz:
https://doaj.org/article/0dc7ea96e7b34192be7de7d6ee8e239c
Autor:
Sara Gargiulo, Virginia Barone, Denise Bonente, Tiziana Tamborrino, Giovanni Inzalaco, Lisa Gherardini, Eugenio Bertelli, Mario Chiariello
Publikováno v:
Journal of Imaging, Vol 10, Iss 9, p 217 (2024)
Consuming an unbalanced diet and being overweight represent a global health problem in young people and adults of both sexes, and may lead to metabolic syndrome. The diet-induced obesity (DIO) model in the C57BL/6J mouse substrain that mimics the gra
Externí odkaz:
https://doaj.org/article/b5b6f96dab6045a99679c83905ecce85
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Glioblastoma (GB) is a highly malignant primary brain tumor with limited treatment options and poor prognosis. Despite current treatment approaches, including surgical resection, radiation therapy, and chemotherapy with temozolomide (TMZ), GB remains
Externí odkaz:
https://doaj.org/article/7e97383402ba4496b3103fe3b185346d
Autor:
Lisa Gherardini, Veronica Vetri Buratti, Mirko Maturi, Giovanni Inzalaco, Erica Locatelli, Letizia Sambri, Sara Gargiulo, Virginia Barone, Denise Bonente, Eugenio Bertelli, Silvia Tortorella, Lorenzo Franci, Antonio Fioravanti, Mauro Comes Franchini, Mario Chiariello
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Glioblastoma multiforme (GBM) is the most aggressive primary tumor of the central nervous system and the diagnosis is often dismal. GBM pharmacological treatment is strongly limited by its intracranial location beyond the blood–brain barri
Externí odkaz:
https://doaj.org/article/a673b4ee4c384c1aae31d45e333b78fc
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 381-384 (2022)
Aberrant production of reactive oxygen species (ROS) from dysfunctional mitochondria leads to oxidative stress and DNA damage, which induces the cellular senescence stress response pathway. This, while exerting strong beneficial suppressive effects o
Externí odkaz:
https://doaj.org/article/a0b54d8f5cba41188b29de16b455bc8b
Autor:
Adelfia Talà, Flora Guerra, Matteo Calcagnile, Roberta Romano, Silvia Caterina Resta, Aurora Paiano, Mario Chiariello, Graziano Pizzolante, Cecilia Bucci, Pietro Alifano
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-28 (2022)
Abstract Background In Neisseria meningitidis the HrpA/HrpB two-partner secretion system (TPS) was implicated in diverse functions including meningococcal competition, biofilm formation, adherence to epithelial cells, intracellular survival and vacuo
Externí odkaz:
https://doaj.org/article/754f4998b3984f1f860f16affc7ecfe6
Autor:
Denise Bonente, Laura Bianchi, Rossana De Salvo, Claudio Nicoletti, Elena De Benedetto, Tommaso Bacci, Luca Bini, Giovanni Inzalaco, Lorenzo Franci, Mario Chiariello, Gian Marco Tosi, Eugenio Bertelli, Virginia Barone
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9728 (2023)
Epiretinal membranes (ERMs) are sheets of tissue that pathologically develop in the vitreoretinal interface leading to progressive vision loss. They are formed by different cell types and by an exuberant deposition of extracellular matrix proteins. R
Externí odkaz:
https://doaj.org/article/5ad6cf58a18e4d90bdced1ad302693a0
Autor:
Leire Iralde-Lorente, Ylenia Cau, Letizia Clementi, Lorenzo Franci, Giusy Tassone, Daniela Valensin, Mattia Mori, Adriano Angelucci, Mario Chiariello, Maurizio Botta
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 657-664 (2019)
14-3-3 are regulatory proteins that through protein–protein interactions (PPI) with numerous binding partners could be involved in several human diseases, including cancer, neurodegenerative disorders, and pathogens infections. Following our resear
Externí odkaz:
https://doaj.org/article/0387ca67151143d8bee11b1f00a12246
Publikováno v:
Autophagy Reports. 1:381-384
Autor:
Barone, Denise Bonente, Laura Bianchi, Rossana De Salvo, Claudio Nicoletti, Elena De Benedetto, Tommaso Bacci, Luca Bini, Giovanni Inzalaco, Lorenzo Franci, Mario Chiariello, Gian Marco Tosi, Eugenio Bertelli, Virginia
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9728
Epiretinal membranes (ERMs) are sheets of tissue that pathologically develop in the vitreoretinal interface leading to progressive vision loss. They are formed by different cell types and by an exuberant deposition of extracellular matrix proteins. R