Výsledky vyhledávání - "Marinelli Andreoli, A."

Pharmacokinetic and Pharmacodynamic Head-to-Head Comparison of Clinical, Equivalent Doses of Insulin Glargine 300 units · mL−1 and Insulin Degludec 100 units · mL−1 in Type 1 Diabetes

Autor: Patrizia Cioli, Carmine G. Fanelli, Paola Candeloro, Angela Gambelunghe, Geremia B. Bolli, Chiara Pascucci, Paola Lucidi, Anna Marinelli Andreoli, Francesca Porcellati

Publikováno v: Diabetes Care. 44:125-132

OBJECTIVE To prove equivalence of individual, clinically titrated basal insulin doses of glargine 300 units ⋅ mL−1 (Gla-300) and degludec 100 units ⋅ mL−1 (Deg-100) under steady state conditions in a single-blind, randomized, crossover study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4010ae39cedf000b8d43df12fd7118c
https://doi.org/10.2337/dc20-1033

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895-P: Improved Glycemic Control with Insulin Glargine 300 U/mL vs. Glargine 100 U/mL in Type 1 Diabetes

Autor: Carmine G. Fanelli, Patrizia Cioli, Paola Candeloro, Francesca Porcellati, Anna Marinelli Andreoli, Lucidi Paola, Geremia B. Bolli

Publikováno v: Diabetes. 69

PK/PD of clinical doses of Glargine 300 U/mL (Gla-300) and Gla-100 differ (Diabetes Care 2019;42:85), but any clinical relevance has been difficult to demonstrate. Aim: to demonstrate that PK/PD differences of individual doses of Gla-300 vs. Gla-100

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90a4b9ab094f7b23b37ae41734e2b772
https://doi.org/10.2337/db20-895-p

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Pharmacokinetic and Pharmacodynamic Head-to-Head Comparison of Clinical, Equivalent Doses of Insulin Glargine 300 units · mL

Autor: Paola, Lucidi, Paola, Candeloro, Patrizia, Cioli, Anna, Marinelli Andreoli, Chiara, Pascucci, Angela, Gambelunghe, Geremia B, Bolli, Carmine G, Fanelli, Francesca, Porcellati

Publikováno v: Diabetes care. 44(1)

To prove equivalence of individual, clinically titrated basal insulin doses of glargine 300 units ⋅ mLSubjects with T1D (At the end of 3 months, Gla-300 and Deg-100 reduced slightly and, similarly, A1C versus baseline. Clamp average plasma glucose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::596f880e2ef872ee4a206b7a0f42ebe7
https://pubmed.ncbi.nlm.nih.gov/33444161

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Greater Suppression of Glucagon, Lipolysis, and Ketogenesis with Insulin Glargine U300 as Compared with Glargine U100 in Type 1 Diabetes Mellitus

Autor: Francesca Porcellati, Carmine G. Fanelli, Anna Marinelli Andreoli, Paola Candeloro, Patrizia Cioli, Geremia B. Bolli, Paola Lucidi

Publikováno v: Diabetes technologytherapeutics. 22(1)

The aim of this study was to establish the effects of clinical doses of Gla-300 versus Gla-100 on suppression of glucagon, lipolysis, and ketogenesis in type 1 diabetes mellitus (T1DM). Eighteen persons with T1DM (age 40 ± 12 years, diabetes duratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b8fb4447ab6ec38a4aea8428f653cb
https://pubmed.ncbi.nlm.nih.gov/31411498

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Lower Pharmacokinetic and Pharmacodynamic Within-Day Variability of Individual Clinical Doses of Insulin Glargine 300 U/ml vs. Glargine 100 U/ml in T1DM

Autor: Anna Marinelli Andreoli, Geremia B. Bolli, Paola Lucidi, Patrizia Cioli, Francesca Porcellati, Carmine G. Fanelli, Paola Candeloro

Publikováno v: Diabetes. 67

Previous studies have examined variability of pharmacokinetics (PK, plasma insulin concentration) and pharmacodynamics (PD, glucose infusion rate, GIR) of basal insulins at steady-state (SS) and at fixed doses in all subjects studied. To establish wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf8a7cd2bf0e3e6800e39dcc57e99528
https://doi.org/10.2337/db18-1042-p

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