Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marinella Antolini"'
Autor:
Alessandro Gozzi, Giuliano Turrini, Laura Piccoli, Mario Massagrande, David Amantini, Marinella Antolini, Prisca Martinelli, Nicola Cesari, Dino Montanari, Michela Tessari, Mauro Corsi, Angelo Bifone
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16406 (2011)
Orexins are neuro-modulatory peptides involved in the control of diverse physiological functions through interaction with two receptors, orexin-1 (OX1R) and orexin-2 (OX2R). Recent evidence in pre-clinical models points toward a putative dichotomic r
Externí odkaz:
https://doaj.org/article/3299f87eee5845e8bf0c7c7b59902405
Autor:
Romano Di Fabio, Emilio Merlo Pich, Marinella Antolini, Mauro Corsi, Elisabetta Perdona, Stefania Faedo
Publikováno v:
European Journal of Pharmacology. 692:1-9
In this work the pharmacology and the receptor kinetics of the following orexin receptor antagonists SB-649868, ACT-078573, JNJ-10397049, MK-6096 and Roche-Cp were evaluated at human OX(1) and OX(2) orexin receptors by using functional and receptor b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07c3947d07dcc91703f7ba959df4aa8
https://doi.org/10.1016/j.ejphar.2012.07.007
https://doi.org/10.1016/j.ejphar.2012.07.007
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6405-6407
A new class of selective orexin 2 antagonist was identified among commercial products. Initial SAR was obtained using commercial derivatives only prior to starting ad hoc medicinal chemistry activities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d656a1e3f865d6011c491b92ae59a6c
https://doi.org/10.1016/j.bmcl.2010.09.090
https://doi.org/10.1016/j.bmcl.2010.09.090
Autor:
Andrea Bozzoli, Gordon J. Kennedy, Antonella Ursini, Marinella Antolini, Chiara Ghiron, Tino Rossi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:1023-1028
A preliminary exploration of analogues of 4,5-bis(3,5-dichlorophenyl)-2-trifluoromethyl-1H-imidazole, 1, as novel antibacterial agents was carried out to determine the basic features of the structure responsible for the observed biological activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ddf0b3fa7ccb9cf89d8df3c19aa40f
https://doi.org/10.1016/s0960-894x(99)00112-2
https://doi.org/10.1016/s0960-894x(99)00112-2
Autor:
Nicola Cesari, Laura Piccoli, Angelo Bifone, David Amantini, Prisca Martinelli, Marinella Antolini, Dino Montanari, Alessandro Gozzi, Mauro Corsi, Mario Massagrande, Giuliano Turrini, Michela Tessari
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 1, p e16406 (2011)
PLoS ONE, Vol 6, Iss 1, p e16406 (2011)
Orexins are neuro-modulatory peptides involved in the control of diverse physiological functions through interaction with two receptors, orexin-1 (OX1R) and orexin-2 (OX2R). Recent evidence in pre-clinical models points toward a putative dichotomic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1460d2f7ecd0302baaf1724f2e09f5
http://hdl.handle.net/11562/348301
http://hdl.handle.net/11562/348301
Autor:
Gordon J. Kennedy, Tino Rossi, Andrea Bozzoli, Antonella Ursini, Marinella Antolini, Chiara Ghiron
Publikováno v:
ChemInform. 30
A preliminary exploration of analogues of 4,5-bis(3,5-dichlorophenyl)-2-trifluoromethyl-1H-imidazole, 1, as novel antibacterial agents was carried out to determine the basic features of the structure responsible for the observed biological activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d522f2474c855d450f71bea4e4b332e8
https://doi.org/10.1002/chin.199932116
https://doi.org/10.1002/chin.199932116