TIE-2 Signaling Activation by Angiopoietin 2 On Myeloid-Derived Suppressor Cells Promotes Melanoma-Specific T-cell Inhibition

Autor: Amélie Marguier, Caroline Laheurte, Benoît Lecoester, Marine Malfroy, Laura Boullerot, Adeline Renaudin, Evan Seffar, Abhishek Kumar, Charlée Nardin, François Aubin, Olivier Adotevi

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of immune suppressive cells detected in several human cancers. In this study, we investigated the features and immune suppressive function of a novel subset of monocytic MDSC overexpr

Externí odkaz: https://doaj.org/article/4ad89da152d74e058957e595e319c057

Response to Chemoimmunotherapy Is Associated With Expansion of Systemic Antitumor CD4+ Th1 Response in Metastatic Non–Small Cell Lung Cancer

Autor: Mylène Wespiser, Amélie Marguier, Benoît Lecoester, Thibault Richard, Laura Boullerot, Marine Malfroy, Abhishek Kumar, Caroline Laheurte, Olivier Adotévi

Publikováno v: Journal of Immunotherapy.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08ee9fc41862c3a36bc0fcce3923cdf8
https://doi.org/10.1097/cji.0000000000000454

Interplay between plasmacytoid dendritic cells and tumor-specific T cells in peripheral blood influences long-term survival in non-small cell lung carcinoma

Autor: Caroline Laheurte, Evan Seffar, Eléonore Gravelin, Julie Lecuelle, Adeline Renaudin, Laura Boullerot, Marine Malfroy, Amélie Marguier, Benoit Lecoester, Béatrice Gaugler, Philippe Saas, Caroline Truntzer, Francois Ghiringhelli, Olivier Adotevi

Publikováno v: Cancer immunology, immunotherapy : CII.

Plasmacytoid dendritic cells (pDCs) represent a subset of antigen-presenting cells that play an ambivalent role in cancer immunity. Here, we investigated the clinical significance of circulating pDCs and their interaction with tumor-specific T cell r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebcad0a6b3b5beb03c398636dc0bd0d
https://pubmed.ncbi.nlm.nih.gov/35989364

The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

Autor: Joyce Taylor-Papadimitriou, Uzma Hasan, Christine Carreira, Marine Malfroy, Nadège Goutagny, Peggy Parroche, Claudia Zannetti, Giorgio Trinchieri, Didier Picard, Martin Müller, Guillaume Roblot, Ishraq Hussain, Ruslan Medzhitov, Massimo Tommasino, Bakary S. Sylla

Publikováno v: The Journal of experimental medicine
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 210, No 7 (2013) pp. 1369-87

HPV16-positive cervical cancer lesions contain NFκB–ERα nuclear complexes to repress the TLR9 promoter.
Human papillomavirus type 16 (HPV16) and other oncogenic viruses have been reported to deregulate immunity by suppressing the function of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bf0ccad010abafcdcee8ada63afb90

Seroprevalence of hepatitis B and C virus in HIV-1 and HIV-2 infected Gambians

Autor: Kevin Peterson, Abraham Alabi, Sarah Rowland-Jones, Matthew Cotten, Maimuna Mendy, Ingrid Peterson, Richard S. Tedder, Hilton Whittle, Ramu Sarge-Njie, Assan Jaye, Marine Malfroy, Adam Jeng, Modou L Jobarteh, Andrew J. Hall

Publikováno v: Virology Journal, Vol 7, Iss 1, p 230 (2010)
Virology Journal

Background The prevalence of HIV/hepatitis co-infection in sub-Saharan Africa is not well documented, while both HIV and HBV are endemic in this area. Objective The aim of this study is to determine the seroprevalence of HBV and HCV virus in HIV-infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae543251bd735f6df389de7ba95b692b
http://www.virologyj.com/content/7/1/230