Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marine Geoffroy"'
Publikováno v:
Cells, Vol 13, Iss 10, p 800 (2024)
In recent years, clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) protein have emerged as a revolutionary gene editing tool to treat inherited disorders affecting different organ systems, such as blood a
Externí odkaz:
https://doaj.org/article/6317b1de847948b1bf4bd16131e5c54e
Autor:
Marine Geoffroy, Louna Pili, Valentina Buffa, Maëlle Caroff, Anne Bigot, Evelyne Gicquel, Grégory Rouby, Isabelle Richard, Romain Fragnoud
Publikováno v:
Cells, Vol 12, Iss 20, p 2444 (2023)
Limb-Girdle Muscular Dystrophy R9 (LGMDR9) is a dystroglycanopathy caused by Fukutin-related protein (FKRP) defects leading to the deficiency of α-DG glycosylation, essential to membrane integrity. Recombinant adeno-associated viral vector (rAAV) ge
Externí odkaz:
https://doaj.org/article/2adc7642487e43eab2c01182c7f5af74
Autor:
Celine Bruge, Marine Geoffroy, Manon Benabides, Emilie Pellier, Evelyne Gicquel, Jamila Dhiab, Lucile Hoch, Isabelle Richard, Xavier Nissan
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1428 (2022)
Limb girdle muscular dystrophies (LGMD), caused by mutations in 29 different genes, are the fourth most prevalent group of genetic muscle diseases. Although the link between LGMD and its genetic origins has been determined, LGMD still represent an un
Externí odkaz:
https://doaj.org/article/82d64902387c4a7782f09cefe76a00fd
Autor:
Marine Lemesle, Marine Geoffroy, Fabien Alpy, Catherine-Laure Tomasetto, Sandra Kuntz, Isabelle Grillier-Vuissoz
Publikováno v:
Cancers; Volume 14; Issue 20; Pages: 5026
Triple-negative breast cancer (TNBC) is an aggressive subtype that constitutes 15–20% of breast cancer cases worldwide. Current therapies often evolve into chemoresistance and lead to treatment failure. About 77% of the TNBC lacks claudin-1 (CLDN1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000895cf8a8ad0f6d9e3ea29834044e9
Autor:
Marine Geoffroy, Marine Lemesle, Alexandra Kleinclauss, Sabine Mazerbourg, Levy Batista, Muriel Barberi-Heyob, Thierry Bastogne, Wilfrid Boireau, Alain Rouleau, Dorian Dupommier, Michel Boisbrun, Corinne Comoy, Stéphane Flament, Isabelle Grillier-Vuissoz, Sandra Kuntz
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (12), pp.6859. ⟨10.3390/ijms23126859⟩
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6859
International Journal of Molecular Sciences, 2022, 23 (12), pp.6859. ⟨10.3390/ijms23126859⟩
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6859
International audience; Breast cancer is one of the leading causes of cancer-related death among females worldwide. A major challenge is to develop innovative therapy in order to treat breast cancer subtypes resistant to current treatment. In the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd7c9c08564ae6e1f4e819996f0ed51
https://pubmed.ncbi.nlm.nih.gov/35743305
https://pubmed.ncbi.nlm.nih.gov/35743305
Publikováno v:
Molecular Biology Reports
Molecular Biology Reports, Springer Verlag, 2020, 47 (10), pp.7643-7653. ⟨10.1007/s11033-020-05835-3⟩
Molecular Biology Reports, Springer Verlag, 2020, 47 (10), pp.7643-7653. ⟨10.1007/s11033-020-05835-3⟩
International audience; Triple-negative “claudin 1 low” subtype represents around 15% of breast cancer and displays poor prognosis. The loss of claudin 1 is correlated with increased invasiveness and higher recurrence of the disease. Claudin 1 co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19e556901f4713bcc68a04087b0e1c0
https://doi.org/10.1007/s11033-020-05835-3
https://doi.org/10.1007/s11033-020-05835-3
Autor:
Marine Geoffroy, Andrea Bordessa, Michel Boisbrun, Sandra Kuntz, Stéphane Flament, Sabine Mazerbourg, Isabelle Grillier-Vuissoz, Audrey Berthe
Publikováno v:
Current Topics in Medicinal Chemistry
Current Topics in Medicinal Chemistry, Bentham Science Publishers, 2016, 16 (19), pp.2115-2124. ⟨10.2174/1568026616666160216153036⟩
Current Topics in Medicinal Chemistry, Bentham Science Publishers, 2016, 16 (19), pp.2115-2124. ⟨10.2174/1568026616666160216153036⟩
International audience; The existence of unresponsive tumors and the appearance of resistant tumors during the course of treatments both justify that we increase urgently the panel of pharmacological molecules able to fight cancer. An interesting str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b54a8195cb9a4d1a7a969c39bf45948
https://doi.org/10.2174/1568026616666160216153036
https://doi.org/10.2174/1568026616666160216153036
Autor:
Stéphane Flament, Alexandra Kleinclauss, Sébastien Hupont, Marine Geoffroy, Stéphanie Grandemange, Isabelle Grillier-Vuissoz, Michel Boisbrun, Sandra Kuntz
Publikováno v:
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, Springer Verlag, 2017, 165 (3), pp.517-527. ⟨10.1007/s10549-017-4378-2⟩
Breast Cancer Research and Treatment, Springer Verlag, 2017, 165 (3), pp.517-527. ⟨10.1007/s10549-017-4378-2⟩
International audience; PURPOSE:40% of triple-negative breast cancer (TNBC) do not express claudin-1, a major constituent of tight junction. Patients with these "claudin-1-low" tumors present a higher relapse incidence. A major challenge in oncology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e07d1c1e66775d29474ba16b3dac5c2
https://hal.archives-ouvertes.fr/hal-01589665
https://hal.archives-ouvertes.fr/hal-01589665
Autor:
Marine Geoffroy, Alexandra Kleinclauss, Stéphanie Grandemange, Sébastien Hupont, Michel Boisbrun, Stéphane Flament, Isabelle Grillier-Vuissoz, Sandra Kuntz
Publikováno v:
Breast Cancer Research and Treatment. 165:529-529
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80a80d1a5dd14d50e910ca7665df4d2
https://doi.org/10.1007/s10549-017-4402-6
https://doi.org/10.1007/s10549-017-4402-6